hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05402
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRMO | tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O) | UniProt NCBI |
| BCL2L11 | Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death) | UniProt NCBI |
| MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT) | UniProt NCBI |
| RHPN2 | Rhophilin-2 (76 kDa RhoB effector protein) (GTP-Rho-binding protein 2) (p76RBE) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3611 | 0.00180886504004 | 0.5 | BCL2L11 MCL1 | Photodynamic therapy-induced AP-1 survival signaling. |
| WP:WP254 | 0.00438725142358 | 0.5 | BCL2L11 MCL1 | Apoptosis |
| WP:WP1772 | 0.00540505574756 | 0.5 | BCL2L11 MCL1 | Apoptosis Modulation and Signaling |
| KEGG:04210 | 0.0153578793248 | 0.5 | BCL2L11 MCL1 | Apoptosis |
| MIRNA:hsa-miR-148b-5p | 0.0213987373532 | 0.5 | BCL2L11 MCL1 | hsa-miR-148b-5p |
| KEGG:05206 | 0.0241976216174 | 0.5 | BCL2L11 MCL1 | MicroRNAs in cancer |
| MIRNA:hsa-miR-661 | 0.0255635225094 | 0.75 | MCL1 RHPN2 TRMO | hsa-miR-661 |
| WP:WP4399 | 0.0333519728792 | 0.25 | MCL1 | MicroRNA network associated with chronic lymphocytic leukemia |
| MIRNA:hsa-miR-6508-5p | 0.0369995799824 | 0.5 | BCL2L11 MCL1 | hsa-miR-6508-5p |
| MIRNA:hsa-miR-8067 | 0.0381896870696 | 0.5 | BCL2L11 MCL1 | hsa-miR-8067 |
| CORUM:5823 | 0.0499140284799 | 0.25 | MCL1 | MCL1-BAK1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MCL1 | BCL2L11 | 0.927 | 0.844 | bioplex (BCL2L11,MCL1) bioplex_WMM |
| BCL2L11 | RHPN2 | 0.731 | 0.736 | bioplex (BCL2L11) bioplex_WMM |
| RHPN2 | TRMO | 0.149 | 0.41 | bioplex (TRMO) bioplex_WMM |
| MCL1 | RHPN2 | 0.008 | 0.083 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05402 has an average edge precision of 0.518 which is ranked 2403 out of all 6965 complexes.
Related Complexes