hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05411
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ANKS6 | Ankyrin repeat and SAM domain-containing protein 6 (Ankyrin repeat domain-containing protein 14) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6) | UniProt NCBI |
| NEK8 | Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a) | UniProt NCBI |
| ZNF214 | Zinc finger protein 214 (BWSCR2-associated zinc finger protein 1) (BAZ-1) | UniProt NCBI |
| ANKS3 | Ankyrin repeat and SAM domain-containing protein 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6257 | 3.01612206104e-05 | 0.5 | NEK8 ANKS6 | ANKS6-NEK8-INVS-NPHP3 complex |
| WP:WP4352 | 0.000349541974194 | 0.75 | NEK8 ANKS6 ANKS3 | Ciliary landscape |
| HP:0000105 | 0.00308721029257 | 0.5 | NEK8 ANKS6 | Enlarged kidney |
| WP:WP4656 | 0.00438725142358 | 0.5 | NEK8 ANKS6 | Joubert Syndrome |
| HP:0000090 | 0.0142767163782 | 0.5 | NEK8 ANKS6 | Nephronophthisis |
| HP:0100957 | 0.0214223630957 | 0.5 | NEK8 ANKS6 | Abnormal renal medulla morphology |
| HP:0001650 | 0.0335949626331 | 0.5 | NEK8 ANKS6 | Aortic valve stenosis |
| CORUM:6661 | 0.0499140284799 | 0.25 | NEK8 | NEK8-WWTR1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ANKS6 | NEK8 | 0.115 | 0.384 | gupta (NEK8) boldt (NEK8) boldt_WMM |
| ANKS6 | ANKS3 | 0.051 | 0.296 | boldt (ANKS3,ANKS6) boldt_WMM |
| ZNF214 | ANKS3 | 0.024 | 0.215 | bioplex (ZNF214) bioplex_WMM |
| NEK8 | ANKS3 | 0.008 | 0.015 | boldt (NEK8) boldt_WMM |
Images
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Complex HuMAP2_05411 has an average edge precision of 0.227 which is ranked 5740 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ANKS6 | HuMAP2_02006 HuMAP2_02697 HuMAP2_05411 |
| NEK8 | HuMAP2_02006 HuMAP2_02697 HuMAP2_05411 |
| ZNF214 | HuMAP2_02006 HuMAP2_02544 HuMAP2_05411 HuMAP2_05425 |
| ANKS3 | HuMAP2_02006 HuMAP2_02697 HuMAP2_05411 |