hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_05417

Confidence: Medium High

Genename	Protein Name	Links
EEF1A2	Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1)	UniProt NCBI
EEF1B2	Elongation factor 1-beta (EF-1-beta)	UniProt NCBI
EEF1G	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma)	UniProt NCBI
VARS	Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS)	UniProt NCBI
EIF5B	Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2)	UniProt NCBI
KTN1	Kinectin (CG-1 antigen) (Kinesin receptor)	UniProt NCBI
NXPH2	Neurexophilin-2	UniProt NCBI
QTRT2	Queuine tRNA-ribosyltransferase accessory subunit 2 (Queuine tRNA-ribosyltransferase domain-containing protein 1)	UniProt NCBI
EEF1D	Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4)	UniProt NCBI
CARS	Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP107	5.39212586812e-09	0.5	EEF1G EEF1D EIF5B EEF1A2 EEF1B2	Translation Factors
REAC:R-HSA-72766	2.35796004878e-08	0.7	EEF1G EEF1D EEF1B2 VARS EEF1A2 CARS EIF5B	Translation
REAC:R-HSA-156842	5.82153902075e-05	0.4	EEF1G EEF1D EEF1A2 EEF1B2	Eukaryotic Translation Elongation
GO:0006412	0.000298844044961	0.7	EEF1G EEF1D EEF1B2 VARS EEF1A2 CARS EIF5B	translation
REAC:R-HSA-392499	0.000350378632871	0.8	KTN1 EEF1G EEF1D EEF1B2 VARS EEF1A2 CARS EIF5B	Metabolism of proteins
GO:0043043	0.00040549812451	0.7	EEF1G EEF1D EEF1B2 VARS EEF1A2 CARS EIF5B	peptide biosynthetic process
GO:0043604	0.00141893880443	0.7	EEF1G EEF1D EEF1B2 VARS EEF1A2 CARS EIF5B	amide biosynthetic process
GO:0006518	0.00146550364589	0.7	EEF1G EEF1D EEF1B2 VARS EEF1A2 CARS EIF5B	peptide metabolic process
GO:0008135	0.00487122857055	0.4	EEF1D EIF5B EEF1A2 EEF1B2	translation factor activity, RNA binding
GO:0043603	0.00878187532197	0.7	EEF1G EEF1D EEF1B2 VARS EEF1A2 CARS EIF5B	cellular amide metabolic process
GO:0090079	0.0111017782004	0.4	EEF1D EIF5B EEF1A2 EEF1B2	translation regulator activity, nucleic acid binding
KEGG:00970	0.0181778440105	0.2	CARS VARS	Aminoacyl-tRNA biosynthesis
KEGG:05134	0.0198737758517	0.2	EEF1G EEF1A2	Legionellosis
REAC:R-HSA-379716	0.0232438230146	0.2	CARS VARS	Cytosolic tRNA aminoacylation
GO:0045182	0.0285805055799	0.4	EEF1D EIF5B EEF1A2 EEF1B2	translation regulator activity
GO:0006414	0.0405352109312	0.4	EEF1G EEF1D EEF1A2 EEF1B2	translational elongation

Edges

Protein 1	Protein 2	Score	Precision	Evidence
EEF1D	EEF1G	1.0	0.949	hein_WMM bioplex (EEF1D,EEF1G) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM
VARS	EEF1G	1.0	0.949	hein_WMM bioplex (EEF1G) bioplex_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM
VARS	EEF1D	1.0	0.949	hein_WMM bioplex (EEF1D) bioplex_WMM Malo gupta_WMM fraction boldt_WMM
EEF1B2	VARS	1.0	0.949	hein_WMM bioplex_WMM Malo gupta_WMM fraction boldt_WMM
EEF1B2	EEF1D	1.0	0.949	hein_WMM bioplex (EEF1D) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM
EEF1B2	EEF1G	1.0	0.949	hein_WMM bioplex (EEF1G) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM
EEF1A2	EEF1G	0.982	0.898	bioplex (EEF1A2,EEF1G) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM
EEF1B2	EIF5B	0.628	0.68	boldt youn_WMM gupta_WMM fraction boldt_WMM
CARS	EEF1D	0.32	0.512	hein_WMM bioplex (EEF1D) bioplex_WMM boldt_WMM
CARS	EEF1G	0.21	0.457	hein_WMM bioplex (EEF1G) bioplex_WMM fraction boldt_WMM treiber_WMM
EEF1D	EIF5B	0.145	0.408	boldt youn_WMM gupta_WMM fraction boldt_WMM
EEF1G	KTN1	0.127	0.399	hein_WMM bioplex (EEF1G) bioplex_WMM youn_WMM hein (KTN1) gupta_WMM treiber_WMM
NXPH2	EEF1A2	0.123	0.394	bioplex (NXPH2) bioplex_WMM
EEF1D	KTN1	0.108	0.373	hein_WMM bioplex (EEF1D) bioplex_WMM youn_WMM hein (KTN1) gupta_WMM
EEF1G	EIF5B	0.107	0.372	bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM
EEF1A2	CARS	0.103	0.366	bioplex (EEF1A2) bioplex_WMM fraction
EEF1A2	VARS	0.074	0.357	bioplex (EEF1A2) bioplex_WMM fraction
CARS	QTRT2	0.05	0.297	fraction
EEF1A2	EEF1D	0.044	0.275	bioplex (EEF1A2,EEF1D) bioplex_WMM youn_WMM treiber_WMM
VARS	KTN1	0.009	0.102	hein_WMM bioplex_WMM hein (KTN1) treiber_WMM
CARS	KTN1	0.008	0.026	hein_WMM bioplex_WMM WMM_only treiber_WMM
QTRT2	EIF5B	0.007	0.004	bioplex_WMM youn_WMM WMM_only
VARS	EIF5B	0.007	0.007	gupta_WMM WMM_only boldt_WMM treiber_WMM
QTRT2	EEF1D	0.007	0.003	youn_WMM WMM_only
EIF5B	KTN1	0.007	0.001	hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM
QTRT2	EEF1B2	0.007	0.001	youn_WMM WMM_only
EEF1A2	QTRT2	0.007	0.001	bioplex_WMM WMM_only
NXPH2	EEF1B2	0.007	0.004	bioplex (NXPH2)
EEF1A2	EIF5B	0.007	0.002	bioplex_WMM youn_WMM WMM_only
QTRT2	EEF1G	0.007	0.007	bioplex_WMM boldt youn_WMM boldt_WMM
QTRT2	KTN1	0.006	0.003	bioplex_WMM WMM_only
NXPH2	EEF1G	0.006	0.005	bioplex (NXPH2)
NXPH2	QTRT2	0.004	0.015	bioplex (NXPH2) bioplex_WMM
EEF1A2	EEF1B2	0.004	0.012	bioplex (EEF1A2) bioplex_WMM Guru youn_WMM fraction treiber_WMM
EEF1A2	KTN1	0.004	0.017	bioplex (EEF1A2) bioplex_WMM youn_WMM
QTRT2	VARS	0.003	0.018	fraction
EEF1B2	KTN1	0.0	0.012	hein_WMM bioplex_WMM youn_WMM hein (KTN1) gupta_WMM
CARS	EEF1B2	0.0	0.01	hein_WMM bioplex_WMM fraction boldt_WMM
CARS	EIF5B	0.0	0.009	bioplex_WMM fraction boldt_WMM treiber_WMM
CARS	VARS	0.0	0.001	hein_WMM bioplex_WMM fraction boldt_WMM treiber_WMM

Images

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Complex HuMAP2_05417 has an average edge precision of 0.294 which is ranked 4696 out of all 6965 complexes.

Related Complexes

Genename	Complexes
EEF1A2	HuMAP2_01281 HuMAP2_01520 HuMAP2_04212 HuMAP2_04222 HuMAP2_04357 HuMAP2_04377 HuMAP2_04717 HuMAP2_05036 HuMAP2_05417 HuMAP2_06965
EEF1B2	HuMAP2_01815 HuMAP2_03940 HuMAP2_04717 HuMAP2_05036 HuMAP2_05417 HuMAP2_06437
EEF1G	HuMAP2_02417 HuMAP2_03779 HuMAP2_04222 HuMAP2_04717 HuMAP2_05036 HuMAP2_05417 HuMAP2_06437
VARS	HuMAP2_01815 HuMAP2_04222 HuMAP2_04377 HuMAP2_04717 HuMAP2_05036 HuMAP2_05417 HuMAP2_06437
EIF5B	HuMAP2_03940 HuMAP2_04717 HuMAP2_05036 HuMAP2_05417
KTN1	HuMAP2_04222 HuMAP2_05005 HuMAP2_05036 HuMAP2_05417
NXPH2	HuMAP2_01281 HuMAP2_04212 HuMAP2_04222 HuMAP2_04377 HuMAP2_05417 HuMAP2_06965
QTRT2	HuMAP2_01670 HuMAP2_02591 HuMAP2_05417
EEF1D	HuMAP2_01815 HuMAP2_04222 HuMAP2_04717 HuMAP2_05036 HuMAP2_05417 HuMAP2_06437
CARS	HuMAP2_01607 HuMAP2_01670 HuMAP2_01815 HuMAP2_02591 HuMAP2_03779 HuMAP2_04222 HuMAP2_04717 HuMAP2_05036 HuMAP2_05417

hu.MAP 2.0: Complex View

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Complex: HuMAP2_05417