hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05419
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CCT7 | T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed] | UniProt NCBI |
| DCAF13 | DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) | UniProt NCBI |
| ARFGEF2 | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2) | UniProt NCBI |
| KLHDC8B | Kelch domain-containing protein 8B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-390471 | 0.0070462802506 | 0.5 | CCT7 ARFGEF2 | Association of TriC/CCT with target proteins during biosynthesis |
| REAC:R-HSA-390466 | 0.0399558314157 | 0.5 | CCT7 ARFGEF2 | Chaperonin-mediated protein folding |
| REAC:R-HSA-391251 | 0.0454682616856 | 0.5 | CCT7 ARFGEF2 | Protein folding |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CCT7 | KLHDC8B | 0.08 | 0.352 | bioplex (CCT7) bioplex_WMM |
| CCT7 | ARFGEF2 | 0.027 | 0.228 | fraction treiber_WMM |
| DCAF13 | CCT7 | 0.022 | 0.205 | bioplex (CCT7) bioplex_WMM boldt boldt_WMM treiber_WMM |
| DCAF13 | KLHDC8B | 0.009 | 0.107 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_05419 has an average edge precision of 0.223 which is ranked 5810 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CCT7 | HuMAP2_02480 HuMAP2_04444 HuMAP2_05380 HuMAP2_05419 HuMAP2_05976 HuMAP2_06101 |
| DCAF13 | HuMAP2_01551 HuMAP2_04444 HuMAP2_04789 HuMAP2_05419 HuMAP2_05933 |
| ARFGEF2 | HuMAP2_04365 HuMAP2_04444 HuMAP2_05419 |
| KLHDC8B | HuMAP2_04444 HuMAP2_05380 HuMAP2_05419 HuMAP2_05976 |