hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05429
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NUP50 | Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50) | UniProt NCBI |
| NUP153 | Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-168333 | 0.000633499068778 | 1.0 | NUP50 NUP153 | NEP/NS2 Interacts with the Cellular Export Machinery |
| REAC:R-HSA-5619107 | 0.000633499068778 | 1.0 | NUP50 NUP153 | Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) |
| REAC:R-HSA-168274 | 0.000633499068778 | 1.0 | NUP50 NUP153 | Export of Viral Ribonucleoproteins from Nucleus |
| REAC:R-HSA-170822 | 0.000633499068778 | 1.0 | NUP50 NUP153 | Regulation of Glucokinase by Glucokinase Regulatory Protein |
| REAC:R-HSA-168271 | 0.000633499068778 | 1.0 | NUP50 NUP153 | Transport of Ribonucleoproteins into the Host Nucleus |
| REAC:R-HSA-180910 | 0.000729026706133 | 1.0 | NUP50 NUP153 | Vpr-mediated nuclear import of PICs |
| REAC:R-HSA-180746 | 0.000729026706133 | 1.0 | NUP50 NUP153 | Nuclear import of Rev protein |
| REAC:R-HSA-159227 | 0.000729026706133 | 1.0 | NUP50 NUP153 | Transport of the SLBP independent Mature mRNA |
| REAC:R-HSA-165054 | 0.000779304410004 | 1.0 | NUP50 NUP153 | Rev-mediated nuclear export of HIV RNA |
| REAC:R-HSA-4085377 | 0.000779304410004 | 1.0 | NUP50 NUP153 | SUMOylation of SUMOylation proteins |
| REAC:R-HSA-159230 | 0.000779304410004 | 1.0 | NUP50 NUP153 | Transport of the SLBP Dependant Mature mRNA |
| REAC:R-HSA-3301854 | 0.000831258037338 | 1.0 | NUP50 NUP153 | Nuclear Pore Complex (NPC) Disassembly |
| REAC:R-HSA-177243 | 0.000884887588134 | 1.0 | NUP50 NUP153 | Interactions of Rev with host cellular proteins |
| REAC:R-HSA-176033 | 0.000884887588134 | 1.0 | NUP50 NUP153 | Interactions of Vpr with host cellular proteins |
| REAC:R-HSA-3232142 | 0.000940193062392 | 1.0 | NUP50 NUP153 | SUMOylation of ubiquitinylation proteins |
| REAC:R-HSA-168276 | 0.00111616502594 | 1.0 | NUP50 NUP153 | NS1 Mediated Effects on Host Pathways |
| REAC:R-HSA-159231 | 0.00111616502594 | 1.0 | NUP50 NUP153 | Transport of Mature mRNA Derived from an Intronless Transcript |
| REAC:R-HSA-168253 | 0.00117817419405 | 1.0 | NUP50 NUP153 | Host Interactions with Influenza Factors |
| REAC:R-HSA-159234 | 0.00117817419405 | 1.0 | NUP50 NUP153 | Transport of Mature mRNAs Derived from Intronless Transcripts |
| REAC:R-HSA-168325 | 0.00130722030065 | 1.0 | NUP50 NUP153 | Viral Messenger RNA Synthesis |
| REAC:R-HSA-4570464 | 0.0014429701011 | 1.0 | NUP50 NUP153 | SUMOylation of RNA binding proteins |
| REAC:R-HSA-4615885 | 0.0014429701011 | 1.0 | NUP50 NUP153 | SUMOylation of DNA replication proteins |
| REAC:R-HSA-2980766 | 0.00165916422775 | 1.0 | NUP50 NUP153 | Nuclear Envelope Breakdown |
| KEGG:03013 | 0.00169649664321 | 1.0 | NUP50 NUP153 | RNA transport |
| REAC:R-HSA-194441 | 0.00205300624141 | 1.0 | NUP50 NUP153 | Metabolism of non-coding RNA |
| REAC:R-HSA-191859 | 0.00205300624141 | 1.0 | NUP50 NUP153 | snRNP Assembly |
| REAC:R-HSA-6784531 | 0.00239824647466 | 1.0 | NUP50 NUP153 | tRNA processing in the nucleus |
| REAC:R-HSA-3371453 | 0.00348592080174 | 1.0 | NUP50 NUP153 | Regulation of HSF1-mediated heat shock response |
| REAC:R-HSA-4551638 | 0.00348592080174 | 1.0 | NUP50 NUP153 | SUMOylation of chromatin organization proteins |
| REAC:R-HSA-70171 | 0.00359485582679 | 1.0 | NUP50 NUP153 | Glycolysis |
| REAC:R-HSA-1169408 | 0.00370546677531 | 1.0 | NUP50 NUP153 | ISG15 antiviral mechanism |
| REAC:R-HSA-159236 | 0.00381775364729 | 1.0 | NUP50 NUP153 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-3108214 | 0.004164669804 | 1.0 | NUP50 NUP153 | SUMOylation of DNA damage response and repair proteins |
| REAC:R-HSA-1169410 | 0.00452666927187 | 1.0 | NUP50 NUP153 | Antiviral mechanism by IFN-stimulated genes |
| REAC:R-HSA-72202 | 0.00490375205091 | 1.0 | NUP50 NUP153 | Transport of Mature Transcript to Cytoplasm |
| REAC:R-HSA-5619102 | 0.0052959181411 | 1.0 | NUP50 NUP153 | SLC transporter disorders |
| REAC:R-HSA-70326 | 0.00556574181855 | 1.0 | NUP50 NUP153 | Glucose metabolism |
| REAC:R-HSA-3371556 | 0.00598304676068 | 1.0 | NUP50 NUP153 | Cellular response to heat stress |
| REAC:R-HSA-5578749 | 0.00863268175469 | 1.0 | NUP50 NUP153 | Transcriptional regulation by small RNAs |
| REAC:R-HSA-72306 | 0.00863268175469 | 1.0 | NUP50 NUP153 | tRNA processing |
| REAC:R-HSA-162909 | 0.0123699910758 | 1.0 | NUP50 NUP153 | Host Interactions of HIV factors |
| REAC:R-HSA-168273 | 0.014052618232 | 1.0 | NUP50 NUP153 | Influenza Viral RNA Transcription and Replication |
| REAC:R-HSA-68875 | 0.0144900342557 | 1.0 | NUP50 NUP153 | Mitotic Prophase |
| REAC:R-HSA-211000 | 0.0144900342557 | 1.0 | NUP50 NUP153 | Gene Silencing by RNA |
| REAC:R-HSA-162599 | 0.0147112561527 | 1.0 | NUP50 NUP153 | Late Phase of HIV Life Cycle |
| REAC:R-HSA-168255 | 0.0158425044898 | 1.0 | NUP50 NUP153 | Influenza Life Cycle |
| REAC:R-HSA-162587 | 0.0177396498492 | 1.0 | NUP50 NUP153 | HIV Life Cycle |
| REAC:R-HSA-168254 | 0.0182306954237 | 1.0 | NUP50 NUP153 | Influenza Infection |
| REAC:R-HSA-5619115 | 0.0202619146601 | 1.0 | NUP50 NUP153 | Disorders of transmembrane transporters |
| REAC:R-HSA-3108232 | 0.0229517718172 | 1.0 | NUP50 NUP153 | SUMO E3 ligases SUMOylate target proteins |
| REAC:R-HSA-2990846 | 0.0246461304377 | 1.0 | NUP50 NUP153 | SUMOylation |
| REAC:R-HSA-913531 | 0.0252243240322 | 1.0 | NUP50 NUP153 | Interferon Signaling |
| REAC:R-HSA-162906 | 0.0414841334642 | 1.0 | NUP50 NUP153 | HIV Infection |
| REAC:R-HSA-72203 | 0.046079515598 | 1.0 | NUP50 NUP153 | Processing of Capped Intron-Containing Pre-mRNA |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NUP50 | NUP153 | 1.0 | 0.949 | hein_WMM bioplex (NUP50) bioplex_WMM Guru boldt youn_WMM hein (NUP153) gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_05429 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NUP50 | HuMAP2_01285 HuMAP2_01473 HuMAP2_03236 HuMAP2_04098 HuMAP2_05429 HuMAP2_06117 HuMAP2_06218 |
| NUP153 | HuMAP2_01285 HuMAP2_01473 HuMAP2_01705 HuMAP2_03834 HuMAP2_04098 HuMAP2_04845 HuMAP2_05429 |