hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05431
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ACTR2 | Actin-related protein 2 (Actin-like protein 2) | UniProt NCBI |
| ARPC1B | Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:27 | 3.51943927099e-05 | 1.0 | ARPC1B ACTR2 | Arp2/3 protein complex |
| REAC:R-HSA-5663213 | 0.000997174460113 | 1.0 | ARPC1B ACTR2 | RHO GTPases Activate WASPs and WAVEs |
| REAC:R-HSA-3928662 | 0.00124185928562 | 1.0 | ARPC1B ACTR2 | EPHB-mediated forward signaling |
| REAC:R-HSA-2029482 | 0.00286750504412 | 1.0 | ARPC1B ACTR2 | Regulation of actin dynamics for phagocytic cup formation |
| REAC:R-HSA-2029480 | 0.0052959181411 | 1.0 | ARPC1B ACTR2 | Fcgamma receptor (FCGR) dependent phagocytosis |
| REAC:R-HSA-2682334 | 0.00612550025498 | 1.0 | ARPC1B ACTR2 | EPH-Ephrin signaling |
| GO:0005885 | 0.0162296428096 | 1.0 | ARPC1B ACTR2 | Arp2/3 protein complex |
| HPA:028010_23 | 0.0449382117201 | 1.0 | ARPC1B ACTR2 | lymph node; germinal center cells[Approved,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACTR2 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru hein (ACTR2) Malo fraction treiber_WMM |
Images
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Complex HuMAP2_05431 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ACTR2 | HuMAP2_01726 HuMAP2_04323 HuMAP2_05365 HuMAP2_05431 HuMAP2_05568 HuMAP2_05797 |
| ARPC1B | HuMAP2_04323 HuMAP2_05365 HuMAP2_05431 HuMAP2_05568 HuMAP2_05797 |