hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_05438

Confidence: Medium

Genename	Protein Name	Links
VPS4B	Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1)	UniProt NCBI
VPS9D1	VPS9 domain-containing protein 1 (Protein ATP-BL)	UniProt NCBI
ZFYVE19	Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19)	UniProt NCBI
VPS4A	Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-162588	0.00379215175563	0.5	VPS4B VPS4A	Budding and maturation of HIV virion
REAC:R-HSA-917729	0.00466369436644	0.5	VPS4B VPS4A	Endosomal Sorting Complex Required For Transport (ESCRT)
GO:0044878	0.0162267366884	0.5	VPS4A ZFYVE19	mitotic cytokinesis checkpoint
KEGG:04217	0.0226863463099	0.5	VPS4B VPS4A	Necroptosis
GO:0090611	0.0270421395626	0.5	VPS4B VPS4A	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
GO:0009838	0.0405595771497	0.5	VPS4A ZFYVE19	abscission
GO:0032466	0.0405595771497	0.5	VPS4A ZFYVE19	negative regulation of cytokinesis

Protein 1	Protein 2	Score	Precision	Evidence
VPS4A	ZFYVE19	1.0	0.949	bioplex (VPS4A) bioplex_WMM
VPS4A	VPS4B	0.996	0.927	bioplex (VPS4A,VPS4B) bioplex_WMM fraction
VPS4B	VPS9D1	0.05	0.296	hein_WMM hein (VPS4B)
ZFYVE19	VPS4B	0.008	0.06	bioplex_WMM WMM_only

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ComplexPrecisionDistribution

Complex HuMAP2_05438 has an average edge precision of 0.558 which is ranked 2147 out of all 6965 complexes.

Related Complexes

Genename	Complexes
VPS4B	HuMAP2_05141 HuMAP2_05438 HuMAP2_06668
VPS9D1	HuMAP2_05438 HuMAP2_06668
ZFYVE19	HuMAP2_04495 HuMAP2_05141 HuMAP2_05438
VPS4A	HuMAP2_04495 HuMAP2_05141 HuMAP2_05438