hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05448
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPP4R3A | Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) | UniProt NCBI |
| PPP4R3B | Serine/threonine-protein phosphatase 4 regulatory subunit 3B (SMEK homolog 2) | UniProt NCBI |
| DHX38 | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38) | UniProt NCBI |
| PPP4C | Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X) | UniProt NCBI |
| PPP4R2 | Serine/threonine-protein phosphatase 4 regulatory subunit 2 | UniProt NCBI |
| SLC4A1AP | Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) | UniProt NCBI |
| TRMT1 | tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) | UniProt NCBI |
| RBM11 | Splicing regulator RBM11 (RNA-binding motif protein 11) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1245 | 1.16880143691e-05 | 0.25 | PPP4R2 PPP4C | Protein phosphatase 4 complex |
| CORUM:1750 | 7.00904180673e-05 | 0.25 | PPP4R2 PPP4C | PPP4C-PPP4R2-Gemin3-Gemin4 complex |
| KEGG:04922 | 0.000682513094161 | 0.375 | PPP4R3B PPP4C PPP4R3A | Glucagon signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPP4C | PPP4R2 | 1.0 | 0.949 | hein_WMM bioplex (PPP4R2) bioplex_WMM Guru boldt youn_WMM hein (PPP4C,PPP4R2) gupta_WMM fraction boldt_WMM |
| PPP4R2 | PPP4R3A | 1.0 | 0.949 | hein_WMM bioplex (PPP4R2,PPP4R3A) bioplex_WMM Guru boldt youn_WMM hein (PPP4R2,PPP4R3A) Malo gupta_WMM fraction boldt_WMM |
| PPP4R2 | PPP4R3B | 1.0 | 0.949 | hein_WMM bioplex (PPP4R2) bioplex_WMM youn_WMM hein (PPP4R2) gupta_WMM |
| PPP4C | PPP4R3A | 0.998 | 0.944 | hein_WMM bioplex (PPP4R3A) bioplex_WMM Guru boldt youn_WMM hein (PPP4C,PPP4R3A) gupta_WMM fraction boldt_WMM |
| PPP4R2 | SLC4A1AP | 0.172 | 0.432 | hein_WMM bioplex (PPP4R2) youn_WMM hein (PPP4R2) fraction boldt_WMM |
| RBM11 | SLC4A1AP | 0.134 | 0.406 | bioplex (RBM11) bioplex_WMM youn_WMM |
| DHX38 | PPP4R2 | 0.11 | 0.379 | hein_WMM bioplex (PPP4R2) bioplex_WMM youn_WMM gupta_WMM |
| PPP4C | PPP4R3B | 0.074 | 0.357 | hein_WMM bioplex_WMM youn_WMM hein (PPP4C) gupta_WMM |
| PPP4R3A | PPP4R3B | 0.071 | 0.352 | hein_WMM bioplex (PPP4R3A) bioplex_WMM youn_WMM gupta_WMM |
| DHX38 | PPP4R3A | 0.025 | 0.217 | hein_WMM bioplex_WMM youn_WMM hein (PPP4R3A) gupta_WMM |
| DHX38 | TRMT1 | 0.023 | 0.206 | youn_WMM fraction |
| PPP4R3A | SLC4A1AP | 0.021 | 0.195 | hein_WMM youn_WMM hein (PPP4R3A) boldt_WMM |
| PPP4C | SLC4A1AP | 0.009 | 0.108 | hein_WMM youn_WMM WMM_only boldt_WMM |
| DHX38 | SLC4A1AP | 0.009 | 0.101 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| DHX38 | PPP4C | 0.008 | 0.088 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DHX38 | PPP4R3B | 0.008 | 0.079 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RBM11 | PPP4C | 0.007 | 0.011 | youn_WMM WMM_only |
| RBM11 | PPP4R2 | 0.007 | 0.008 | youn_WMM WMM_only |
| SLC4A1AP | PPP4R3B | 0.007 | 0.008 | hein_WMM youn_WMM WMM_only |
| RBM11 | PPP4R3A | 0.007 | 0.006 | youn_WMM WMM_only |
| DHX38 | RBM11 | 0.007 | 0.009 | youn_WMM WMM_only |
| PPP4R2 | TRMT1 | 0.007 | 0.008 | youn_WMM WMM_only |
| SLC4A1AP | TRMT1 | 0.007 | 0.004 | youn_WMM WMM_only |
| PPP4C | TRMT1 | 0.007 | 0.003 | youn_WMM WMM_only |
| RBM11 | PPP4R3B | 0.007 | 0.013 | youn_WMM WMM_only |
| RBM11 | TRMT1 | 0.007 | 0.009 | youn_WMM WMM_only |
| TRMT1 | PPP4R3B | 0.007 | 0.004 | youn_WMM WMM_only |
| PPP4R3A | TRMT1 | 0.0 | 0.003 | youn_WMM fraction |
Images
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Complex HuMAP2_05448 has an average edge precision of 0.243 which is ranked 5489 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPP4R3A | HuMAP2_02081 HuMAP2_05448 HuMAP2_06695 HuMAP2_06754 |
| PPP4R3B | HuMAP2_05448 HuMAP2_06468 HuMAP2_06695 |
| DHX38 | HuMAP2_00024 HuMAP2_05448 |
| PPP4C | HuMAP2_02007 HuMAP2_02081 HuMAP2_04313 HuMAP2_05448 HuMAP2_06468 HuMAP2_06695 |
| PPP4R2 | HuMAP2_02081 HuMAP2_05448 HuMAP2_06468 HuMAP2_06695 |
| SLC4A1AP | HuMAP2_02196 HuMAP2_03218 HuMAP2_03256 HuMAP2_04621 HuMAP2_05448 |
| TRMT1 | HuMAP2_04709 HuMAP2_05448 |
| RBM11 | HuMAP2_01715 HuMAP2_02196 HuMAP2_03218 HuMAP2_04621 HuMAP2_05448 HuMAP2_06075 |