hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05459
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SAE1 | SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A) [Cleaved into: SUMO-activating enzyme subunit 1, N-terminally processed] | UniProt NCBI |
| EEF1AKNMT | eEF1A lysine and N-terminal methyltransferase (eEF1A-KNMT) (Methyltransferase-like protein 13) [Includes: eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)] | UniProt NCBI |
| GCLC | Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4518 | 0.0428416541517 | 0.333333333333 | GCLC | Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases |
| CORUM:5756 | 0.0499776345577 | 0.333333333333 | SAE1 | SUA1-UBA2 complex |
| CORUM:7186 | 0.0499776345577 | 0.333333333333 | GCLC | Glutamate-cysteine ligase |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SAE1 | EEF1AKNMT | 0.179 | 0.438 | bioplex_WMM fraction |
| GCLC | SAE1 | 0.031 | 0.238 | fraction |
Images
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Complex HuMAP2_05459 has an average edge precision of 0.338 which is ranked 4147 out of all 6965 complexes.
Related Complexes