hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05460
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SERINC1 | Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2) | UniProt NCBI |
| MT-CO1 | Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I) | UniProt NCBI |
| TMEM214 | Transmembrane protein 214 | UniProt NCBI |
| MFSD8 | Major facilitator superfamily domain-containing protein 8 (Ceroid-lipofuscinosis neuronal protein 7) | UniProt NCBI |
| ADIPOR2 | Adiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II) | UniProt NCBI |
| ASGR2 | Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (C-type lectin domain family 4 member H2) (Hepatic lectin H2) (HL-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000603 | 0.0497285764978 | 0.333333333333 | MT-CO1 MFSD8 | Central scotoma |
| CORUM:6410 | 0.0499726005494 | 0.166666666667 | MT-CO1 | MITRAC7-COX1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SERINC1 | ASGR2 | 0.117 | 0.391 | bioplex (ASGR2) |
| TMEM214 | ASGR2 | 0.101 | 0.364 | bioplex (ASGR2) |
| MFSD8 | ASGR2 | 0.051 | 0.296 | bioplex (ASGR2) |
| ASGR2 | ADIPOR2 | 0.038 | 0.263 | bioplex (ASGR2) |
| ASGR2 | MT-CO1 | 0.022 | 0.202 | bioplex (ASGR2) |
| SERINC1 | MFSD8 | 0.011 | 0.152 | bioplex_WMM WMM_only |
| SERINC1 | MT-CO1 | 0.01 | 0.131 | bioplex_WMM WMM_only |
| MFSD8 | MT-CO1 | 0.009 | 0.11 | bioplex_WMM WMM_only |
| TMEM214 | ADIPOR2 | 0.008 | 0.023 | bioplex_WMM gupta_WMM WMM_only |
| SERINC1 | ADIPOR2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| MFSD8 | ADIPOR2 | 0.007 | 0.017 | bioplex_WMM WMM_only |
| MT-CO1 | ADIPOR2 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| TMEM214 | SERINC1 | 0.006 | 0.0 | bioplex_WMM WMM_only |
| TMEM214 | MFSD8 | 0.006 | 0.003 | bioplex_WMM WMM_only |
| TMEM214 | MT-CO1 | 0.006 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05460 has an average edge precision of 0.131 which is ranked 6825 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SERINC1 | HuMAP2_02035 HuMAP2_05339 HuMAP2_05460 |
| MT-CO1 | HuMAP2_04240 HuMAP2_05251 HuMAP2_05460 |
| TMEM214 | HuMAP2_00717 HuMAP2_02035 HuMAP2_05460 |
| MFSD8 | HuMAP2_02035 HuMAP2_05460 HuMAP2_05923 |
| ADIPOR2 | HuMAP2_05460 |
| ASGR2 | HuMAP2_02035 HuMAP2_05460 |