hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05467
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PTPRU | Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi) | UniProt NCBI |
| PTPRK | Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) | UniProt NCBI |
| CACNA2D2 | Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2] | UniProt NCBI |
| COL6A2 | Collagen alpha-2(VI) chain | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9006934 | 0.0147563350021 | 0.75 | COL6A2 PTPRU PTPRK | Signaling by Receptor Tyrosine Kinases |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| COL6A2 | PTPRK | 0.268 | 0.482 | bioplex (PTPRK) bioplex_WMM |
| PTPRK | CACNA2D2 | 0.045 | 0.283 | bioplex (PTPRK) bioplex_WMM |
| PTPRK | PTPRU | 0.021 | 0.195 | bioplex (PTPRU) bioplex_WMM |
| COL6A2 | CACNA2D2 | 0.005 | 0.012 | bioplex_WMM WMM_only |
| CACNA2D2 | PTPRU | 0.004 | 0.008 | bioplex_WMM WMM_only |
| COL6A2 | PTPRU | 0.004 | 0.011 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05467 has an average edge precision of 0.165 which is ranked 6576 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PTPRU | HuMAP2_05467 |
| PTPRK | HuMAP2_04813 HuMAP2_05467 |
| CACNA2D2 | HuMAP2_04813 HuMAP2_05467 |
| COL6A2 | HuMAP2_01383 HuMAP2_04813 HuMAP2_05467 |