hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05471
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ITSN1 | Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) | UniProt NCBI |
| AGXT | Serine--pyruvate aminotransferase (SPT) (EC 2.6.1.51) (Alanine--glyoxylate aminotransferase) (AGT) (EC 2.6.1.44) | UniProt NCBI |
| CLYBL | Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9) | UniProt NCBI |
| GCAT | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) | UniProt NCBI |
| ALDH8A1 | 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase 12) (Aldehyde dehydrogenase family 8 member A1) | UniProt NCBI |
| CAT | Catalase (EC 1.11.1.6) | UniProt NCBI |
| COL4A3 | Collagen alpha-3(IV) chain (Goodpasture antigen) [Cleaved into: Tumstatin] | UniProt NCBI |
| NAGA | Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00630 | 0.00524026179246 | 0.25 | AGXT CAT | Glyoxylate and dicarboxylate metabolism |
| KEGG:00380 | 0.00800794093463 | 0.25 | ALDH8A1 CAT | Tryptophan metabolism |
| KEGG:00260 | 0.00890494757069 | 0.25 | AGXT GCAT | Glycine, serine and threonine metabolism |
| KEGG:01100 | 0.0101915709661 | 0.625 | NAGA ALDH8A1 AGXT CAT GCAT | Metabolic pathways |
| KEGG:04146 | 0.0330272419157 | 0.25 | AGXT CAT | Peroxisome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CAT | AGXT | 0.166 | 0.423 | fraction |
| CAT | NAGA | 0.099 | 0.358 | fraction |
| CAT | GCAT | 0.065 | 0.347 | fraction |
| CAT | CLYBL | 0.043 | 0.269 | fraction |
| CAT | ITSN1 | 0.032 | 0.241 | fraction |
| CAT | ALDH8A1 | 0.021 | 0.187 | fraction |
| CAT | COL4A3 | 0.02 | 0.184 | fraction |
| GCAT | NAGA | 0.0 | 0.01 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05471 has an average edge precision of 0.252 which is ranked 5347 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ITSN1 | HuMAP2_00475 HuMAP2_01747 HuMAP2_02111 HuMAP2_05471 HuMAP2_06613 |
| AGXT | HuMAP2_02401 HuMAP2_02873 HuMAP2_03443 HuMAP2_05471 |
| CLYBL | HuMAP2_02873 HuMAP2_05471 |
| GCAT | HuMAP2_00675 HuMAP2_02873 HuMAP2_05471 |
| ALDH8A1 | HuMAP2_01176 HuMAP2_02517 HuMAP2_04127 HuMAP2_04260 HuMAP2_04645 HuMAP2_05471 |
| CAT | HuMAP2_00027 HuMAP2_00781 HuMAP2_02394 HuMAP2_02873 HuMAP2_03443 HuMAP2_04579 HuMAP2_05471 |
| COL4A3 | HuMAP2_05471 |
| NAGA | HuMAP2_02873 HuMAP2_05471 |