hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05473
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP6V1C1 | V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1) | UniProt NCBI |
| STRADB | STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2) | UniProt NCBI |
| CAB39 | Calcium-binding protein 39 (MO25alpha) (Protein Mo25) | UniProt NCBI |
| CAB39L | Calcium-binding protein 39-like (Antigen MLAA-34) (MO25beta) (Mo25-like protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04150 | 3.10435795123e-07 | 1.0 | ATP6V1C1 CAB39 CAB39L STRADB | mTOR signaling pathway |
| REAC:R-HSA-380972 | 4.41854320762e-06 | 0.75 | CAB39 CAB39L STRADB | Energy dependent regulation of mTOR by LKB1-AMPK |
| REAC:R-HSA-165159 | 1.23194951195e-05 | 0.75 | CAB39 CAB39L STRADB | mTOR signalling |
| KEGG:04152 | 6.09947630131e-05 | 0.75 | CAB39 CAB39L STRADB | AMPK signaling pathway |
| WP:WP1403 | 0.00336828295894 | 0.5 | CAB39 STRADB | AMP-activated Protein Kinase (AMPK) Signaling |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP6V1C1 | CAB39 | 0.997 | 0.93 | fraction |
| CAB39L | CAB39 | 0.992 | 0.912 | bioplex (CAB39L) bioplex_WMM |
| CAB39 | STRADB | 0.907 | 0.83 | bioplex (STRADB) bioplex_WMM |
| ATP6V1C1 | CAB39L | 0.59 | 0.664 | fraction |
Images
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Complex HuMAP2_05473 has an average edge precision of 0.834 which is ranked 826 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP6V1C1 | HuMAP2_00348 HuMAP2_04879 HuMAP2_05473 |
| STRADB | HuMAP2_00480 HuMAP2_01280 HuMAP2_02879 HuMAP2_03165 HuMAP2_04879 HuMAP2_05473 HuMAP2_06034 |
| CAB39 | HuMAP2_00480 HuMAP2_01280 HuMAP2_02879 HuMAP2_04879 HuMAP2_05473 HuMAP2_06034 |
| CAB39L | HuMAP2_00480 HuMAP2_01236 HuMAP2_01280 HuMAP2_03829 HuMAP2_04879 HuMAP2_05473 HuMAP2_06034 |