hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05490
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| APEX1 | DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (APE-1) (REF-1) (Redox factor-1) [Cleaved into: DNA-(apurinic or apyrimidinic site) lyase, mitochondrial] | UniProt NCBI |
| YARS | Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-73930 | 0.0499173803268 | 0.5 | APEX1 | Abasic sugar-phosphate removal via the single-nucleotide replacement pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| APEX1 | YARS | 0.668 | 0.701 | bioplex (APEX1) bioplex_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_05490 has an average edge precision of 0.701 which is ranked 1365 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| APEX1 | HuMAP2_00204 HuMAP2_01328 HuMAP2_01654 HuMAP2_04565 HuMAP2_05490 |
| YARS | HuMAP2_02855 HuMAP2_04565 HuMAP2_05490 HuMAP2_05624 |