hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05505
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TMEM132A | Transmembrane protein 132A (HSPA5-binding protein 1) | UniProt NCBI |
| ZBTB33 | Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33) | UniProt NCBI |
| MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7) | UniProt NCBI |
| CLSTN1 | Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)] | UniProt NCBI |
| SHLD2 | Shieldin complex subunit 2 (Protein FAM35A) (RINN1-REV7-interacting novel NHEJ regulator 2) (Shield complex subunit 2) | UniProt NCBI |
| BMPER | BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2) | UniProt NCBI |
| DEFA5 | Defensin-5 (Defensin, alpha 5) (HD5(20-94)) [Cleaved into: HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94)] | UniProt NCBI |
| IFNGR1 | Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119) | UniProt NCBI |
| CILP2 | Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2] | UniProt NCBI |
| ARHGAP19 | Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7578 | 3.01890677263e-05 | 0.2 | MAD2L2 SHLD2 | Shieldin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DEFA5 | ARHGAP19 | 0.743 | 0.739 | bioplex (DEFA5) bioplex_WMM |
| DEFA5 | CILP2 | 0.315 | 0.509 | bioplex (DEFA5) bioplex_WMM |
| SHLD2 | DEFA5 | 0.25 | 0.474 | bioplex (DEFA5) bioplex_WMM |
| BMPER | DEFA5 | 0.221 | 0.466 | bioplex (DEFA5) bioplex_WMM |
| DEFA5 | ZBTB33 | 0.098 | 0.357 | bioplex (DEFA5) bioplex_WMM |
| MAD2L2 | SHLD2 | 0.066 | 0.349 | hein_WMM hein (MAD2L2) |
| CLSTN1 | DEFA5 | 0.045 | 0.282 | bioplex (DEFA5) bioplex_WMM |
| MAD2L2 | IFNGR1 | 0.026 | 0.215 | bioplex (IFNGR1) bioplex_WMM |
| DEFA5 | TMEM132A | 0.025 | 0.211 | bioplex (DEFA5) bioplex_WMM |
| BMPER | CILP2 | 0.01 | 0.106 | bioplex_WMM WMM_only |
| BMPER | SHLD2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| SHLD2 | ARHGAP19 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| SHLD2 | CILP2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| BMPER | TMEM132A | 0.008 | 0.081 | bioplex_WMM WMM_only |
| BMPER | ARHGAP19 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| CILP2 | ZBTB33 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| BMPER | CLSTN1 | 0.008 | 0.044 | bioplex_WMM WMM_only |
| ARHGAP19 | CILP2 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| SHLD2 | ZBTB33 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CILP2 | TMEM132A | 0.008 | 0.006 | bioplex_WMM WMM_only |
| SHLD2 | TMEM132A | 0.008 | 0.012 | bioplex_WMM WMM_only |
| BMPER | ZBTB33 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| CLSTN1 | SHLD2 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| ARHGAP19 | ZBTB33 | 0.007 | 0.011 | bioplex_WMM WMM_only |
| CLSTN1 | CILP2 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| ARHGAP19 | TMEM132A | 0.007 | 0.006 | bioplex_WMM WMM_only |
| CLSTN1 | ARHGAP19 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| MAD2L2 | ZBTB33 | 0.007 | 0.003 | gupta_WMM WMM_only |
| IFNGR1 | ZBTB33 | 0.007 | 0.002 | gupta_WMM WMM_only |
| CLSTN1 | MAD2L2 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| TMEM132A | ZBTB33 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CLSTN1 | ZBTB33 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CLSTN1 | TMEM132A | 0.006 | 0.004 | bioplex_WMM WMM_only |
| IFNGR1 | TMEM132A | 0.006 | 0.004 | bioplex_WMM WMM_only |
| CLSTN1 | IFNGR1 | 0.005 | 0.014 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05505 has an average edge precision of 0.126 which is ranked 6850 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TMEM132A | HuMAP2_05505 |
| ZBTB33 | HuMAP2_05505 HuMAP2_06791 HuMAP2_07009 |
| MAD2L2 | HuMAP2_03200 HuMAP2_04874 HuMAP2_05505 |
| CLSTN1 | HuMAP2_02767 HuMAP2_03717 HuMAP2_03980 HuMAP2_05505 |
| SHLD2 | HuMAP2_03200 HuMAP2_04874 HuMAP2_05505 |
| BMPER | HuMAP2_01656 HuMAP2_05020 HuMAP2_05505 |
| DEFA5 | HuMAP2_03407 HuMAP2_03717 HuMAP2_04225 HuMAP2_05505 |
| IFNGR1 | HuMAP2_03200 HuMAP2_05505 |
| CILP2 | HuMAP2_03717 HuMAP2_05151 HuMAP2_05505 HuMAP2_05579 |
| ARHGAP19 | HuMAP2_03407 HuMAP2_03717 HuMAP2_05505 |