hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05507
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| JPT2 | Jupiter microtubule associated homolog 2 (Hematological and neurological expressed 1-like protein) (HN1-like protein) | UniProt NCBI |
| DMC1 | Meiotic recombination protein DMC1/LIM15 homolog | UniProt NCBI |
| RAD51 | DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A) | UniProt NCBI |
| FIGNL1 | Fidgetin-like protein 1 (EC 3.6.4.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000150 | 0.00270494046827 | 0.5 | DMC1 RAD51 | recombinase activity |
| GO:0000730 | 0.00270494046827 | 0.5 | DMC1 RAD51 | DNA recombinase assembly |
| GO:0090735 | 0.00270494046827 | 0.5 | DMC1 RAD51 | DNA repair complex assembly |
| GO:0045003 | 0.0162267366884 | 0.5 | DMC1 RAD51 | double-strand break repair via synthesis-dependent strand annealing |
| GO:0042148 | 0.0270421395626 | 0.5 | DMC1 RAD51 | strand invasion |
| REAC:R-HSA-912446 | 0.0356320611636 | 0.5 | DMC1 RAD51 | Meiotic recombination |
| CORUM:2824 | 0.0499140284799 | 0.25 | RAD51 | BRCA1-RAD51 complex |
| CORUM:5683 | 0.0499140284799 | 0.25 | RAD51 | hRAD51C-hXRCC3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DMC1 | RAD51 | 0.488 | 0.616 | bioplex (DMC1) bioplex_WMM |
| FIGNL1 | RAD51 | 0.026 | 0.216 | bioplex (FIGNL1) bioplex_WMM |
| FIGNL1 | JPT2 | 0.021 | 0.189 | bioplex (FIGNL1,JPT2) bioplex_WMM youn_WMM gupta_WMM |
| RAD51 | JPT2 | 0.007 | 0.002 | youn_WMM WMM_only |
Images
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Complex HuMAP2_05507 has an average edge precision of 0.256 which is ranked 5291 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| JPT2 | HuMAP2_02904 HuMAP2_05507 HuMAP2_06287 |
| DMC1 | HuMAP2_02087 HuMAP2_02714 HuMAP2_04317 HuMAP2_04403 HuMAP2_05507 |
| RAD51 | HuMAP2_02087 HuMAP2_04317 HuMAP2_05507 |
| FIGNL1 | HuMAP2_00390 HuMAP2_02904 HuMAP2_02997 HuMAP2_05507 HuMAP2_06287 |