hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05511
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PARD3 | Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha) | UniProt NCBI |
| PARD6B | Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B) | UniProt NCBI |
| PTPN21 | Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:956 | 1.00675659188e-05 | 0.666666666667 | PARD6B PARD3 | PAR-3-PAR-6B-PRKCI complex |
| REAC:R-HSA-420029 | 0.000702607572674 | 0.666666666667 | PARD6B PARD3 | Tight junction interactions |
| KEGG:04390 | 0.00445520604942 | 0.666666666667 | PARD6B PARD3 | Hippo signaling pathway |
| KEGG:04530 | 0.00464549646756 | 0.666666666667 | PARD6B PARD3 | Tight junction |
| KEGG:04360 | 0.00601503157228 | 0.666666666667 | PARD6B PARD3 | Axon guidance |
| REAC:R-HSA-421270 | 0.00632193682699 | 0.666666666667 | PARD6B PARD3 | Cell-cell junction organization |
| KEGG:04015 | 0.0066119256567 | 0.666666666667 | PARD6B PARD3 | Rap1 signaling pathway |
| KEGG:04144 | 0.0117748506163 | 0.666666666667 | PARD6B PARD3 | Endocytosis |
| REAC:R-HSA-446728 | 0.0165866686159 | 0.666666666667 | PARD6B PARD3 | Cell junction organization |
| KEGG:05165 | 0.0214257750703 | 0.666666666667 | PARD6B PARD3 | Human papillomavirus infection |
| REAC:R-HSA-1500931 | 0.0350118981581 | 0.666666666667 | PARD6B PARD3 | Cell-Cell communication |
| CORUM:5558 | 0.0499776345577 | 0.333333333333 | PARD6B | PAR6-CDC42 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PARD6B | PARD3 | 1.0 | 0.949 | hein_WMM bioplex (PARD6B) bioplex_WMM hein (PARD6B) |
| PARD6B | PTPN21 | 0.989 | 0.903 | bioplex (PARD6B) bioplex_WMM |
| PTPN21 | PARD3 | 0.009 | 0.097 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05511 has an average edge precision of 0.65 which is ranked 1654 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PARD3 | HuMAP2_01053 HuMAP2_01276 HuMAP2_01528 HuMAP2_02149 HuMAP2_02503 HuMAP2_05511 |
| PARD6B | HuMAP2_00450 HuMAP2_01276 HuMAP2_01528 HuMAP2_02149 HuMAP2_02503 HuMAP2_05511 |
| PTPN21 | HuMAP2_00582 HuMAP2_03756 HuMAP2_05511 |