hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05532
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MYH2 | Myosin-2 (Myosin heavy chain 2) (Myosin heavy chain 2a) (MyHC-2a) (Myosin heavy chain IIa) (MyHC-IIa) (Myosin heavy chain, skeletal muscle, adult 2) | UniProt NCBI |
| TLE3 | Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3) | UniProt NCBI |
| MYH1 | Myosin-1 (Myosin heavy chain 1) (Myosin heavy chain 2x) (MyHC-2x) (Myosin heavy chain IIx/d) (MyHC-IIx/d) (Myosin heavy chain, skeletal muscle, adult 1) | UniProt NCBI |
| MYH8 | Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04530 | 0.000132953253798 | 0.75 | MYH8 MYH2 MYH1 | Tight junction |
| KEGG:05130 | 0.000242354366577 | 0.75 | MYH8 MYH2 MYH1 | Pathogenic Escherichia coli infection |
| GO:0005859 | 0.000296207880886 | 0.75 | MYH8 MYH2 MYH1 | muscle myosin complex |
| GO:0016460 | 0.000558907067709 | 0.75 | MYH8 MYH2 MYH1 | myosin II complex |
| GO:0016459 | 0.00197902980402 | 0.75 | MYH8 MYH2 MYH1 | myosin complex |
| CORUM:6770 | 0.0499140284799 | 0.25 | TLE3 | TBX20-TLE3 repressor complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TLE3 | MYH2 | 1.0 | 0.949 | bioplex (TLE3) bioplex_WMM |
| MYH1 | TLE3 | 0.994 | 0.919 | bioplex (TLE3) bioplex_WMM |
| MYH8 | TLE3 | 0.882 | 0.818 | bioplex (TLE3) bioplex_WMM |
| MYH1 | MYH2 | 0.011 | 0.141 | bioplex_WMM WMM_only boldt_WMM |
| MYH1 | MYH8 | 0.01 | 0.126 | bioplex_WMM WMM_only |
| MYH8 | MYH2 | 0.008 | 0.094 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05532 has an average edge precision of 0.508 which is ranked 2457 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MYH2 | HuMAP2_03505 HuMAP2_05500 HuMAP2_05532 |
| TLE3 | HuMAP2_02012 HuMAP2_05532 HuMAP2_05545 |
| MYH1 | HuMAP2_01077 HuMAP2_05532 |
| MYH8 | HuMAP2_01077 HuMAP2_02631 HuMAP2_05532 |