hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05538
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDZK1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (CFTR-associated protein of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3) | UniProt NCBI |
| FRYL | Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein) | UniProt NCBI |
| ABCC4 | Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) | UniProt NCBI |
| SH2D5 | SH2 domain-containing protein 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7042 | 0.0499140284799 | 0.25 | PDZK1 | PDZK1-PLCB3- SSTR2 complex |
| CORUM:7043 | 0.0499140284799 | 0.25 | PDZK1 | PDZK1-PLCB3- SSTR3 complex |
| CORUM:7044 | 0.0499140284799 | 0.25 | PDZK1 | PDZK1-PLCB3- SSTR4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDZK1 | SH2D5 | 0.877 | 0.811 | bioplex (PDZK1) bioplex_WMM |
| PDZK1 | ABCC4 | 0.579 | 0.661 | bioplex (PDZK1) bioplex_WMM |
| PDZK1 | FRYL | 0.52 | 0.633 | bioplex (PDZK1) bioplex_WMM |
| SH2D5 | ABCC4 | 0.008 | 0.088 | bioplex_WMM WMM_only |
| SH2D5 | FRYL | 0.008 | 0.087 | bioplex_WMM WMM_only |
| ABCC4 | FRYL | 0.008 | 0.059 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05538 has an average edge precision of 0.39 which is ranked 3427 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDZK1 | HuMAP2_01486 HuMAP2_03516 HuMAP2_05538 HuMAP2_06269 |
| FRYL | HuMAP2_05538 HuMAP2_05687 HuMAP2_06084 |
| ABCC4 | HuMAP2_05538 HuMAP2_06269 |
| SH2D5 | HuMAP2_01486 HuMAP2_03516 HuMAP2_05538 HuMAP2_06269 |