hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05554
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZEB1 | Zinc finger E-box-binding homeobox 1 (NIL-2-A zinc finger protein) (Negative regulator of IL2) (Transcription factor 8) (TCF-8) | UniProt NCBI |
| RUFY3 | Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar) | UniProt NCBI |
| DCAF15 | DDB1- and CUL4-associated factor 15 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2943 | 0.0142843877495 | 0.333333333333 | ZEB1 | Hypoxia-mediated EMT and Stemness |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZEB1 | DCAF15 | 0.759 | 0.749 | bioplex (DCAF15) bioplex_WMM |
| DCAF15 | RUFY3 | 0.123 | 0.394 | bioplex (DCAF15) bioplex_WMM |
| ZEB1 | RUFY3 | 0.007 | 0.006 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05554 has an average edge precision of 0.383 which is ranked 3492 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZEB1 | HuMAP2_01227 HuMAP2_05554 |
| RUFY3 | HuMAP2_05554 HuMAP2_05874 |
| DCAF15 | HuMAP2_01227 HuMAP2_05554 |