hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05557
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MACF1 | Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) | UniProt NCBI |
| HEYL | Hairy/enhancer-of-split related with YRPW motif-like protein (hHeyL) (Class B basic helix-loop-helix protein 33) (bHLHb33) (Hairy-related transcription factor 3) (HRT-3) (hHRT3) | UniProt NCBI |
| FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) | UniProt NCBI |
| PGGT1B | Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) | UniProt NCBI |
| AMMECR1L | AMMECR1-like protein | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004662 | 0.00450823411379 | 0.4 | PGGT1B FNTA | CAAX-protein geranylgeranyltransferase activity |
| GO:0005953 | 0.00450823411379 | 0.4 | PGGT1B FNTA | CAAX-protein geranylgeranyltransferase complex |
| GO:0004661 | 0.0450641792523 | 0.4 | PGGT1B FNTA | protein geranylgeranyltransferase activity |
| CORUM:419 | 0.0499494897235 | 0.2 | FNTA | Farnesyltransferase |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PGGT1B | AMMECR1L | 0.977 | 0.892 | bioplex (AMMECR1L) bioplex_WMM |
| MACF1 | AMMECR1L | 0.704 | 0.725 | bioplex (AMMECR1L) bioplex_WMM |
| HEYL | PGGT1B | 0.297 | 0.496 | bioplex (HEYL) bioplex_WMM |
| AMMECR1L | FNTA | 0.029 | 0.232 | bioplex (AMMECR1L) bioplex_WMM |
| PGGT1B | MACF1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| MACF1 | FNTA | 0.007 | 0.006 | bioplex_WMM WMM_only |
| HEYL | FNTA | 0.0 | 0.008 | bioplex (HEYL) bioplex_WMM |
| PGGT1B | FNTA | 0.0 | 0.002 | bioplex_WMM fraction |
Images
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Complex HuMAP2_05557 has an average edge precision of 0.296 which is ranked 4662 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MACF1 | HuMAP2_00050 HuMAP2_05557 HuMAP2_05620 |
| HEYL | HuMAP2_00050 HuMAP2_00208 HuMAP2_01483 HuMAP2_05557 |
| FNTA | HuMAP2_00121 HuMAP2_00759 HuMAP2_01483 HuMAP2_01541 HuMAP2_02291 HuMAP2_03630 HuMAP2_05557 |
| PGGT1B | HuMAP2_00050 HuMAP2_00208 HuMAP2_01483 HuMAP2_05557 HuMAP2_05620 |
| AMMECR1L | HuMAP2_00050 HuMAP2_00208 HuMAP2_01483 HuMAP2_01541 HuMAP2_05557 HuMAP2_05620 |