hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05559
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PABPC1 | Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) | UniProt NCBI |
| PABPC4 | Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP) | UniProt NCBI |
| PAIP1 | Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03013 | 1.76006400333e-05 | 1.0 | PABPC1 PABPC4 PAIP1 | RNA transport |
| CORUM:1307 | 3.35555483123e-05 | 0.666666666667 | PABPC1 PAIP1 | Multiprotein complex (mRNA turnover) |
| WP:WP107 | 0.00117249358059 | 0.666666666667 | PABPC1 PAIP1 | Translation Factors |
| KEGG:03018 | 0.00127210962765 | 0.666666666667 | PABPC1 PABPC4 | RNA degradation |
| KEGG:03015 | 0.0017077231529 | 0.666666666667 | PABPC1 PABPC4 | mRNA surveillance pathway |
| REAC:R-HSA-429947 | 0.00200655101382 | 0.666666666667 | PABPC1 PAIP1 | Deadenylation of mRNA |
| REAC:R-HSA-429914 | 0.0102859860332 | 0.666666666667 | PABPC1 PAIP1 | Deadenylation-dependent mRNA decay |
| GO:0008494 | 0.0486736709081 | 0.666666666667 | PABPC1 PAIP1 | translation activator activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PABPC1 | PABPC4 | 1.0 | 0.949 | hein_WMM youn (PABPC1) bioplex_WMM youn_WMM hein (PABPC1) gupta_WMM fraction boldt_WMM treiber_WMM |
| PAIP1 | PABPC1 | 0.979 | 0.895 | hein_WMM youn (PABPC1,PAIP1) bioplex_WMM youn_WMM hein (PABPC1) gupta_WMM fraction |
| PAIP1 | PABPC4 | 0.003 | 0.015 | hein_WMM youn (PAIP1) bioplex_WMM youn_WMM gupta_WMM |
Images
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Complex HuMAP2_05559 has an average edge precision of 0.62 which is ranked 1838 out of all 6965 complexes.
Related Complexes