hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05594
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CLEC4A | C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367) | UniProt NCBI |
| UBQLN4 | Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75) | UniProt NCBI |
| SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) | UniProt NCBI |
| UBQLN1 | Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1) | UniProt NCBI |
| NUTF2 | Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15) | UniProt NCBI |
| ACSF3 | Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-) | UniProt NCBI |
| DHFR | Dihydrofolate reductase (EC 1.5.1.3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:687 | 0.0499886427319 | 0.142857142857 | SLC9A3R1 | CFTR-NHERF-beta(2)AR signaling complex |
| CORUM:6702 | 0.0499886427319 | 0.142857142857 | SLC9A3R1 | CXCR2-NHERF1-PLC-beta-3 complex |
| CORUM:6788 | 0.0499886427319 | 0.142857142857 | SLC9A3R1 | SLC9A3R1-ACTN4 complex |
| CORUM:6790 | 0.0499886427319 | 0.142857142857 | SLC9A3R1 | NHERF1-PRKCZ complex |
| CORUM:6791 | 0.0499886427319 | 0.142857142857 | SLC9A3R1 | NHERF1-NPT2A-EZR complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NUTF2 | UBQLN1 | 0.532 | 0.637 | bioplex_WMM fraction |
| UBQLN1 | SLC9A3R1 | 0.511 | 0.63 | bioplex_WMM fraction |
| UBQLN4 | ACSF3 | 0.126 | 0.4 | fraction |
| UBQLN1 | UBQLN4 | 0.101 | 0.364 | bioplex_WMM fraction |
| UBQLN1 | ACSF3 | 0.097 | 0.358 | fraction |
| NUTF2 | UBQLN4 | 0.065 | 0.347 | bioplex_WMM fraction |
| DHFR | UBQLN4 | 0.052 | 0.301 | bioplex_WMM fraction |
| NUTF2 | CLEC4A | 0.051 | 0.296 | fraction |
| UBQLN1 | DHFR | 0.043 | 0.269 | bioplex_WMM fraction |
| DHFR | ACSF3 | 0.007 | 0.003 | youn_WMM WMM_only |
| UBQLN4 | SLC9A3R1 | 0.005 | 0.005 | bioplex_WMM WMM_only |
| DHFR | SLC9A3R1 | 0.005 | 0.008 | bioplex_WMM youn_WMM gupta_WMM fraction |
| NUTF2 | SLC9A3R1 | 0.0 | 0.004 | bioplex_WMM fraction |
| NUTF2 | ACSF3 | 0.0 | 0.002 | fraction |
| ACSF3 | SLC9A3R1 | 0.0 | 0.002 | fraction |
| NUTF2 | DHFR | 0.0 | 0.001 | bioplex_WMM youn_WMM fraction |
Images
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Complex HuMAP2_05594 has an average edge precision of 0.227 which is ranked 5750 out of all 6965 complexes.
Related Complexes