hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05597
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CEP85 | Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21) | UniProt NCBI |
| CEP44 | Centrosomal protein of 44 kDa (Cep44) (HBV PreS1-transactivated protein 3) (PS1TP3) | UniProt NCBI |
| SOX1 | Transcription factor SOX-1 | UniProt NCBI |
| SOX6 | Transcription factor SOX-6 | UniProt NCBI |
| SOX11 | Transcription factor SOX-11 | UniProt NCBI |
| SOX13 | Transcription factor SOX-13 (Islet cell antigen 12) (SRY (Sex determining region Y)-box 13) (Type 1 diabetes autoantigen ICA12) | UniProt NCBI |
| SOX5 | Transcription factor SOX-5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4304 | 0.00105444313284 | 0.285714285714 | SOX6 SOX5 | Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS |
| WP:WP474 | 0.0127011112483 | 0.285714285714 | SOX6 SOX5 | Endochondral Ossification |
| REAC:R-HSA-3769402 | 0.023268809464 | 0.285714285714 | SOX6 SOX13 | Deactivation of the beta-catenin transactivating complex |
| GO:2000741 | 0.0283955176165 | 0.285714285714 | SOX6 SOX5 | positive regulation of mesenchymal stem cell differentiation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SOX13 | SOX5 | 1.0 | 0.949 | bioplex (SOX5) bioplex_WMM |
| SOX6 | SOX5 | 1.0 | 0.949 | bioplex (SOX5) bioplex_WMM |
| CEP85 | SOX13 | 0.94 | 0.853 | bioplex (CEP85) bioplex_WMM |
| SOX11 | SOX5 | 0.901 | 0.826 | bioplex (SOX5) bioplex_WMM |
| CEP85 | SOX5 | 0.762 | 0.749 | bioplex (CEP85) bioplex_WMM |
| SOX1 | SOX5 | 0.702 | 0.723 | bioplex (SOX5) bioplex_WMM |
| CEP85 | CEP44 | 0.264 | 0.481 | youn (CEP85) bioplex (CEP85) bioplex_WMM youn_WMM gupta_WMM gupta (CEP44) |
| SOX6 | SOX11 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SOX1 | SOX11 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SOX1 | SOX6 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SOX6 | SOX13 | 0.008 | 0.093 | bioplex_WMM WMM_only |
| SOX11 | SOX13 | 0.008 | 0.093 | bioplex_WMM WMM_only |
| SOX1 | SOX13 | 0.008 | 0.093 | bioplex_WMM WMM_only |
| SOX5 | CEP44 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| SOX13 | CEP44 | 0.008 | 0.045 | bioplex_WMM WMM_only |
| CEP85 | SOX6 | 0.007 | 0.001 | youn_WMM WMM_only |
Images
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Complex HuMAP2_05597 has an average edge precision of 0.387 which is ranked 3452 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CEP85 | HuMAP2_00461 HuMAP2_00563 HuMAP2_00643 HuMAP2_05597 HuMAP2_06966 |
| CEP44 | HuMAP2_00563 HuMAP2_00643 HuMAP2_04040 HuMAP2_05597 HuMAP2_06966 |
| SOX1 | HuMAP2_00461 HuMAP2_05597 |
| SOX6 | HuMAP2_00461 HuMAP2_05597 |
| SOX11 | HuMAP2_00461 HuMAP2_05597 |
| SOX13 | HuMAP2_00461 HuMAP2_00643 HuMAP2_05597 HuMAP2_06966 |
| SOX5 | HuMAP2_00461 HuMAP2_05597 HuMAP2_06966 |