hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05598
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GDPD2 | Glycerophosphoinositol inositolphosphodiesterase GDPD2 (EC 3.1.4.43) (Glycerophosphodiester phosphodiesterase 3) (Glycerophosphodiester phosphodiesterase domain-containing protein 2) (Osteoblast differentiation promoting factor) | UniProt NCBI |
| PLXDC2 | Plexin domain-containing protein 2 (Tumor endothelial marker 7-related protein) | UniProt NCBI |
| AKR1C4 | Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (3-alpha-HSD1) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.357) (Chlordecone reductase) (CDR) (EC 1.1.1.225) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4) (HAKRA) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00120 | 0.0499753562667 | 0.333333333333 | AKR1C4 | Primary bile acid biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AKR1C4 | GDPD2 | 0.446 | 0.59 | bioplex (AKR1C4) bioplex_WMM |
| AKR1C4 | PLXDC2 | 0.207 | 0.455 | bioplex (AKR1C4) bioplex_WMM |
| PLXDC2 | GDPD2 | 0.007 | 0.013 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05598 has an average edge precision of 0.353 which is ranked 3902 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GDPD2 | HuMAP2_03661 HuMAP2_05598 |
| PLXDC2 | HuMAP2_01018 HuMAP2_03661 HuMAP2_05598 |
| AKR1C4 | HuMAP2_00882 HuMAP2_01811 HuMAP2_03661 HuMAP2_05598 |