hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05624
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HSPA8 | Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) | UniProt NCBI |
| PRKDC | DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460) | UniProt NCBI |
| METTL21A | Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A) | UniProt NCBI |
| CNBP | Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9) | UniProt NCBI |
| YARS | Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8876725 | 0.00161668141155 | 0.4 | METTL21A HSPA8 | Protein methylation |
| CORUM:1183 | 0.00271386118461 | 0.4 | PRKDC HSPA8 | CDC5L complex |
| MIRNA:hsa-miR-4461 | 0.0482780268961 | 0.4 | HSPA8 CNBP | hsa-miR-4461 |
| CORUM:360 | 0.0499494897235 | 0.2 | PRKDC | Artemis-DNA-PK complex |
| CORUM:361 | 0.0499494897235 | 0.2 | PRKDC | Artemis-DNA-PK complex |
| CORUM:6114 | 0.0499494897235 | 0.2 | HSPA8 | BAG1-HSC70 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| METTL21A | HSPA8 | 0.791 | 0.759 | bioplex (HSPA8,METTL21A) bioplex_WMM boldt boldt_WMM |
| CNBP | HSPA8 | 0.682 | 0.711 | bioplex (CNBP) fraction treiber_WMM |
| HSPA8 | PRKDC | 0.551 | 0.643 | hein_WMM bioplex (HSPA8) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| HSPA8 | YARS | 0.549 | 0.643 | bioplex (YARS) boldt fraction boldt_WMM treiber_WMM |
| METTL21A | PRKDC | 0.007 | 0.001 | WMM_only boldt_WMM |
| CNBP | YARS | 0.0 | 0.015 | fraction |
| PRKDC | YARS | 0.0 | 0.009 | bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| CNBP | PRKDC | 0.0 | 0.003 | fraction |
Images
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Complex HuMAP2_05624 has an average edge precision of 0.348 which is ranked 3994 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HSPA8 | HuMAP2_01130 HuMAP2_05624 |
| PRKDC | HuMAP2_01370 HuMAP2_02284 HuMAP2_05624 HuMAP2_06176 HuMAP2_06621 |
| METTL21A | HuMAP2_00689 HuMAP2_01418 HuMAP2_04281 HuMAP2_05624 |
| CNBP | HuMAP2_00850 HuMAP2_04408 HuMAP2_05398 HuMAP2_05624 |
| YARS | HuMAP2_02855 HuMAP2_04565 HuMAP2_05490 HuMAP2_05624 |