hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05639
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CRYAB | Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component) | UniProt NCBI |
| NYNRIN | Protein NYNRIN (NYN domain and retroviral integrase catalytic domain-containing protein) (Protein cousin of GIN1) | UniProt NCBI |
| HSPB1 | Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) | UniProt NCBI |
| HSPB6 | Heat shock protein beta-6 (HspB6) (Heat shock 20 kDa-like protein p20) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0002600 | 0.00626129254237 | 0.5 | CRYAB HSPB1 | Hyporeflexia of lower limbs |
| HP:0009027 | 0.0386938410225 | 0.5 | CRYAB HSPB1 | Foot dorsiflexor weakness |
| CORUM:6096 | 0.0499140284799 | 0.25 | CRYAB | alphaB-crystallin-Nav1.5 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CRYAB | HSPB1 | 0.993 | 0.918 | bioplex (CRYAB) bioplex_WMM fraction |
| CRYAB | NYNRIN | 0.379 | 0.549 | bioplex (CRYAB) bioplex_WMM |
| HSPB6 | HSPB1 | 0.316 | 0.51 | bioplex (HSPB6) bioplex_WMM |
| NYNRIN | HSPB1 | 0.008 | 0.034 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05639 has an average edge precision of 0.503 which is ranked 2481 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CRYAB | HuMAP2_02613 HuMAP2_03201 HuMAP2_05639 HuMAP2_06316 |
| NYNRIN | HuMAP2_02613 HuMAP2_03201 HuMAP2_05639 |
| HSPB1 | HuMAP2_02613 HuMAP2_05639 HuMAP2_06316 |
| HSPB6 | HuMAP2_00689 HuMAP2_02613 HuMAP2_05639 HuMAP2_06990 |