hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05641
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| AGFG1 | Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein) | UniProt NCBI |
| ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1) (Submergence-induced protein-like factor) (Sip-L) | UniProt NCBI |
| PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | UniProt NCBI |
| ISOC1 | Isochorismatase domain-containing protein 1 | UniProt NCBI |
| NUDT1 | 7,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55) (2-hydroxy-dATP diphosphatase) (EC 3.6.1.56) (8-oxo-dGTPase) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1) | UniProt NCBI |
| BLVRB | Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) | UniProt NCBI |
| APRT | Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3183 | 0.0499886427319 | 0.142857142857 | PTPN11 | PDGFRA-SHP-2 complex, PDGF stimulated |
| CORUM:3186 | 0.0499886427319 | 0.142857142857 | PTPN11 | GRB2-SHP-2 complex, PDGF stimulated |
| CORUM:7441 | 0.0499886427319 | 0.142857142857 | PTPN11 | HOOK1-SHP2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ADI1 | ISOC1 | 0.384 | 0.55 | bioplex_WMM fraction |
| APRT | ISOC1 | 0.323 | 0.512 | bioplex_WMM fraction treiber_WMM |
| PTPN11 | ISOC1 | 0.1 | 0.361 | bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| AGFG1 | ISOC1 | 0.093 | 0.355 | bioplex_WMM youn_WMM gupta_WMM fraction |
| APRT | ADI1 | 0.089 | 0.356 | bioplex_WMM fraction |
| AGFG1 | BLVRB | 0.078 | 0.352 | bioplex_WMM fraction |
| BLVRB | ADI1 | 0.04 | 0.268 | bioplex_WMM fraction |
| APRT | NUDT1 | 0.036 | 0.264 | bioplex (NUDT1) bioplex_WMM fraction treiber_WMM |
| APRT | PTPN11 | 0.033 | 0.245 | bioplex_WMM youn_WMM gupta_WMM fraction |
| BLVRB | PTPN11 | 0.021 | 0.195 | bioplex_WMM fraction |
| APRT | BLVRB | 0.007 | 0.006 | bioplex_WMM WMM_only treiber_WMM |
| NUDT1 | ADI1 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| BLVRB | NUDT1 | 0.007 | 0.001 | WMM_only treiber_WMM |
| AGFG1 | NUDT1 | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| ADI1 | PTPN11 | 0.007 | 0.005 | bioplex_WMM youn_WMM fraction |
| AGFG1 | APRT | 0.007 | 0.001 | bioplex_WMM gupta_WMM WMM_only |
| NUDT1 | ISOC1 | 0.007 | 0.006 | bioplex (ISOC1) bioplex_WMM |
| NUDT1 | PTPN11 | 0.003 | 0.01 | bioplex_WMM youn_WMM fraction |
| AGFG1 | ADI1 | 0.003 | 0.011 | bioplex_WMM fraction |
| AGFG1 | PTPN11 | 0.0 | 0.002 | bioplex_WMM youn_WMM gupta_WMM fraction |
| BLVRB | ISOC1 | 0.0 | 0.002 | bioplex_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_05641 has an average edge precision of 0.167 which is ranked 6558 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| AGFG1 | HuMAP2_00052 HuMAP2_04441 HuMAP2_04595 HuMAP2_05641 HuMAP2_06294 HuMAP2_06902 |
| ADI1 | HuMAP2_03847 HuMAP2_05332 HuMAP2_05641 |
| PTPN11 | HuMAP2_04051 HuMAP2_05641 HuMAP2_06862 |
| ISOC1 | HuMAP2_04441 HuMAP2_04595 HuMAP2_04682 HuMAP2_05641 |
| NUDT1 | HuMAP2_01889 HuMAP2_05641 |
| BLVRB | HuMAP2_00873 HuMAP2_04052 HuMAP2_04419 HuMAP2_05641 HuMAP2_06294 |
| APRT | HuMAP2_00348 HuMAP2_01436 HuMAP2_05641 |