hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05642
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NDUFAF7 | Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog) | UniProt NCBI |
| NAXD | ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase) | UniProt NCBI |
| TRAP1 | Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) | UniProt NCBI |
| GLO1 | Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1428517 | 0.000984664941346 | 0.75 | TRAP1 GLO1 NDUFAF7 | The citric acid (TCA) cycle and respiratory electron transport |
| MIRNA:hsa-miR-569 | 0.0281535250235 | 0.5 | GLO1 NAXD | hsa-miR-569 |
| REAC:R-HSA-611105 | 0.0435915557177 | 0.5 | TRAP1 NDUFAF7 | Respiratory electron transport |
| MIRNA:hsa-miR-2053 | 0.044421033949 | 0.5 | GLO1 NAXD | hsa-miR-2053 |
| REAC:R-HSA-1430728 | 0.0467536218007 | 1.0 | TRAP1 NDUFAF7 GLO1 NAXD | Metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TRAP1 | NAXD | 0.04 | 0.268 | bioplex (NAXD) fraction |
| TRAP1 | GLO1 | 0.037 | 0.266 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| TRAP1 | NDUFAF7 | 0.02 | 0.185 | bioplex_WMM fraction |
| GLO1 | NDUFAF7 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| NAXD | NDUFAF7 | 0.0 | 0.016 | fraction |
| NAXD | GLO1 | 0.0 | 0.009 | fraction |
Images
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Complex HuMAP2_05642 has an average edge precision of 0.125 which is ranked 6853 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NDUFAF7 | HuMAP2_04245 HuMAP2_05642 |
| NAXD | HuMAP2_01944 HuMAP2_04093 HuMAP2_05514 HuMAP2_05642 HuMAP2_05707 HuMAP2_06011 |
| TRAP1 | HuMAP2_00843 HuMAP2_01944 HuMAP2_02765 HuMAP2_03554 HuMAP2_03790 HuMAP2_05642 HuMAP2_05984 |
| GLO1 | HuMAP2_03302 HuMAP2_05642 HuMAP2_05822 HuMAP2_05969 |