hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05647
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KLHL8 | Kelch-like protein 8 | UniProt NCBI |
| CUL3 | Cullin-3 (CUL-3) | UniProt NCBI |
| KLHL24 | Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1) | UniProt NCBI |
| ANKRD39 | Ankyrin repeat domain-containing protein 39 | UniProt NCBI |
| ARMC5 | Armadillo repeat-containing protein 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7518 | 6.70868171695e-06 | 0.4 | KLHL8 CUL3 | Ubiquitin E3 ligase (CUL3, KLHL8) |
| CORUM:7525 | 2.0123342217e-05 | 0.4 | CUL3 KLHL24 | Ubiquitin E3 ligase (CUL3, KLHL24, RBX1) |
| GO:0031463 | 0.00703245670927 | 0.6 | KLHL8 KLHL24 CUL3 | Cul3-RING ubiquitin ligase complex |
| CORUM:6267 | 0.0499494897235 | 0.2 | CUL3 | Ubiquitin E3 ligase (CUL3, KLHL3) |
| CORUM:6815 | 0.0499494897235 | 0.2 | CUL3 | DRD4-KLHL12-CUL3 complex |
| CORUM:7370 | 0.0499494897235 | 0.2 | CUL3 | CUL3-KCTD11 complex |
| CORUM:7371 | 0.0499494897235 | 0.2 | CUL3 | CUL3-KCTD6 complex |
| CORUM:7526 | 0.0499494897235 | 0.2 | CUL3 | Ubiquitin E3 ligase (CUL3, KLHL25) |
| CORUM:7533 | 0.0499494897235 | 0.2 | CUL3 | Ubiquitin E3 ligase (CUL3, KLHL42) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CUL3 | KLHL8 | 0.591 | 0.664 | hein_WMM bioplex (CUL3) bioplex_WMM hein (CUL3) |
| CUL3 | ANKRD39 | 0.387 | 0.551 | bioplex (CUL3) bioplex_WMM |
| CUL3 | KLHL24 | 0.265 | 0.481 | hein_WMM bioplex (CUL3) bioplex_WMM hein (CUL3) |
| CUL3 | ARMC5 | 0.088 | 0.355 | bioplex (CUL3) bioplex_WMM |
| ANKRD39 | ARMC5 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| KLHL8 | KLHL24 | 0.008 | 0.044 | hein_WMM bioplex_WMM WMM_only |
| KLHL8 | ANKRD39 | 0.008 | 0.042 | bioplex_WMM WMM_only |
| KLHL24 | ANKRD39 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| KLHL8 | ARMC5 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| KLHL24 | ARMC5 | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05647 has an average edge precision of 0.227 which is ranked 5749 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KLHL8 | HuMAP2_00866 HuMAP2_01368 HuMAP2_03890 HuMAP2_05647 |
| CUL3 | HuMAP2_00866 HuMAP2_03890 HuMAP2_05391 HuMAP2_05647 |
| KLHL24 | HuMAP2_03890 HuMAP2_05647 HuMAP2_06858 |
| ANKRD39 | HuMAP2_03890 HuMAP2_05647 |
| ARMC5 | HuMAP2_03890 HuMAP2_05647 HuMAP2_06931 |