hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05648
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DCAF5 | DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22) | UniProt NCBI |
| RWDD2B | RWD domain-containing protein 2B | UniProt NCBI |
| PDLIM5 | PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein) | UniProt NCBI |
| MPP1 | 55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) | UniProt NCBI |
| MYH11 | Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC) | UniProt NCBI |
| ZNF207 | BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (hBuGZ) (Zinc finger protein 207) | UniProt NCBI |
| MKNK1 | MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6254 | 0.0499886427319 | 0.142857142857 | MPP1 | GPC-4.1R-p55 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RWDD2B | PDLIM5 | 0.749 | 0.742 | bioplex (RWDD2B) bioplex_WMM |
| PDLIM5 | ZNF207 | 0.155 | 0.416 | youn_WMM gupta_WMM fraction |
| MYH11 | RWDD2B | 0.105 | 0.369 | bioplex (RWDD2B) bioplex_WMM |
| MPP1 | MYH11 | 0.045 | 0.289 | bioplex (MPP1) bioplex_WMM |
| MKNK1 | PDLIM5 | 0.038 | 0.264 | hein_WMM hein (PDLIM5) |
| RWDD2B | DCAF5 | 0.028 | 0.232 | bioplex (RWDD2B) bioplex_WMM |
| MYH11 | PDLIM5 | 0.008 | 0.028 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MYH11 | DCAF5 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| MYH11 | ZNF207 | 0.007 | 0.002 | gupta_WMM WMM_only |
| DCAF5 | PDLIM5 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| MPP1 | PDLIM5 | 0.0 | 0.009 | youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_05648 has an average edge precision of 0.215 which is ranked 5949 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DCAF5 | HuMAP2_00615 HuMAP2_01629 HuMAP2_05266 HuMAP2_05648 |
| RWDD2B | HuMAP2_00286 HuMAP2_01629 HuMAP2_03321 HuMAP2_04596 HuMAP2_05648 |
| PDLIM5 | HuMAP2_01659 HuMAP2_03321 HuMAP2_04596 HuMAP2_05648 HuMAP2_06669 |
| MPP1 | HuMAP2_00286 HuMAP2_01629 HuMAP2_05648 |
| MYH11 | HuMAP2_00286 HuMAP2_01629 HuMAP2_05648 |
| ZNF207 | HuMAP2_01886 HuMAP2_03822 HuMAP2_05264 HuMAP2_05648 HuMAP2_06909 |
| MKNK1 | HuMAP2_01116 HuMAP2_04988 HuMAP2_05648 |