hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05667
Confidence: Very High
ProteinsGenename | Protein Name | Links |
---|---|---|
SUPT5H | Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein) | UniProt NCBI |
SUPT4H1 | Transcription elongation factor SPT4 (hSPT4) (DRB sensitivity-inducing factor 14 kDa subunit) (DSIF p14) (DRB sensitivity-inducing factor small subunit) (DSIF small subunit) | UniProt NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
CORUM:2860 | 1.67592346237e-06 | 1.0 | SUPT4H1 SUPT5H | DSIF complex (DRB sensitivity-inducing factor complex) |
CORUM:2861 | 1.67592346237e-06 | 1.0 | SUPT4H1 SUPT5H | DSIF complex (DRB sensitivity-inducing factor complex) |
WP:WP3414 | 0.000162072879297 | 1.0 | SUPT4H1 SUPT5H | Initiation of transcription and translation elongation at the HIV-1 LTR |
REAC:R-HSA-167242 | 0.000424008635981 | 1.0 | SUPT4H1 SUPT5H | Abortive elongation of HIV-1 transcript in the absence of Tat |
GO:0032044 | 0.000450823411379 | 1.0 | SUPT4H1 SUPT5H | DSIF complex |
REAC:R-HSA-167238 | 0.000831258037338 | 1.0 | SUPT4H1 SUPT5H | Pausing and recovery of Tat-mediated HIV elongation |
REAC:R-HSA-167243 | 0.000831258037338 | 1.0 | SUPT4H1 SUPT5H | Tat-mediated HIV elongation arrest and recovery |
REAC:R-HSA-113418 | 0.000884887588134 | 1.0 | SUPT4H1 SUPT5H | Formation of the Early Elongation Complex |
REAC:R-HSA-167158 | 0.000884887588134 | 1.0 | SUPT4H1 SUPT5H | Formation of the HIV-1 Early Elongation Complex |
REAC:R-HSA-167287 | 0.000940193062392 | 1.0 | SUPT4H1 SUPT5H | HIV elongation arrest and recovery |
REAC:R-HSA-167290 | 0.000940193062392 | 1.0 | SUPT4H1 SUPT5H | Pausing and recovery of HIV elongation |
REAC:R-HSA-167246 | 0.00158542359541 | 1.0 | SUPT4H1 SUPT5H | Tat-mediated elongation of the HIV-1 transcript |
REAC:R-HSA-167169 | 0.00158542359541 | 1.0 | SUPT4H1 SUPT5H | HIV Transcription Elongation |
REAC:R-HSA-167200 | 0.00158542359541 | 1.0 | SUPT4H1 SUPT5H | Formation of HIV-1 elongation complex containing HIV-1 Tat |
REAC:R-HSA-167152 | 0.00173458078356 | 1.0 | SUPT4H1 SUPT5H | Formation of HIV elongation complex in the absence of HIV Tat |
REAC:R-HSA-75955 | 0.00286750504412 | 1.0 | SUPT4H1 SUPT5H | RNA Polymerase II Transcription Elongation |
REAC:R-HSA-112382 | 0.00286750504412 | 1.0 | SUPT4H1 SUPT5H | Formation of RNA Pol II elongation complex |
REAC:R-HSA-6796648 | 0.00316917126735 | 1.0 | SUPT4H1 SUPT5H | TP53 Regulates Transcription of DNA Repair Genes |
REAC:R-HSA-167172 | 0.004164669804 | 1.0 | SUPT4H1 SUPT5H | Transcription of the HIV genome |
REAC:R-HSA-6807505 | 0.00452666927187 | 1.0 | SUPT4H1 SUPT5H | RNA polymerase II transcribes snRNA genes |
REAC:R-HSA-674695 | 0.00556574181855 | 1.0 | SUPT4H1 SUPT5H | RNA Polymerase II Pre-transcription Events |
REAC:R-HSA-162599 | 0.0147112561527 | 1.0 | SUPT4H1 SUPT5H | Late Phase of HIV Life Cycle |
REAC:R-HSA-162587 | 0.0177396498492 | 1.0 | SUPT4H1 SUPT5H | HIV Life Cycle |
GO:0032785 | 0.0247952876258 | 1.0 | SUPT4H1 SUPT5H | negative regulation of DNA-templated transcription, elongation |
REAC:R-HSA-162906 | 0.0414841334642 | 1.0 | SUPT4H1 SUPT5H | HIV Infection |
Edges
Protein 1 | Protein 2 | Score | Precision | Evidence |
---|---|---|---|---|
SUPT4H1 | SUPT5H | 0.999 | 0.945 | youn (SUPT5H) bioplex_WMM Guru youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_05667 has an average edge precision of 0.945 which is ranked 362 out of all 6965 complexes.
Related Complexes
Genename | Complexes |
---|---|
SUPT5H | HuMAP2_04857 HuMAP2_05384 HuMAP2_05667 HuMAP2_06690 |
SUPT4H1 | HuMAP2_00694 HuMAP2_04857 HuMAP2_05384 HuMAP2_05667 HuMAP2_06690 |