hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05688
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PLPPR1 | Phospholipid phosphatase-related protein type 1 (Lipid phosphate phosphatase-related protein type 1) (Plasticity-related gene 3 protein) (PRG-3) | UniProt NCBI |
| PLPP3 | Phospholipid phosphatase 3 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP) | UniProt NCBI |
| PLPP2 | Phospholipid phosphatase 2 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 2) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0008195 | 7.62876038594e-06 | 1.0 | PLPP3 PLPPR1 PLPP2 | phosphatidate phosphatase activity |
| GO:0042577 | 7.62876038594e-06 | 1.0 | PLPP3 PLPPR1 PLPP2 | lipid phosphatase activity |
| KEGG:04975 | 0.00019456526656 | 0.666666666667 | PLPP3 PLPP2 | Fat digestion and absorption |
| GO:0046839 | 0.000208882724853 | 1.0 | PLPP3 PLPPR1 PLPP2 | phospholipid dephosphorylation |
| WP:WP325 | 0.000242449141731 | 0.666666666667 | PLPP3 PLPP2 | Triacylglyceride Synthesis |
| KEGG:00565 | 0.000250877114117 | 0.666666666667 | PLPP3 PLPP2 | Ether lipid metabolism |
| KEGG:00600 | 0.000366585874156 | 0.666666666667 | PLPP3 PLPP2 | Sphingolipid metabolism |
| KEGG:00561 | 0.000663461273844 | 0.666666666667 | PLPP3 PLPP2 | Glycerolipid metabolism |
| KEGG:00564 | 0.00137503215464 | 0.666666666667 | PLPP3 PLPP2 | Glycerophospholipid metabolism |
| KEGG:04666 | 0.0017077231529 | 0.666666666667 | PLPP3 PLPP2 | Fc gamma R-mediated phagocytosis |
| KEGG:05231 | 0.00174690264746 | 0.666666666667 | PLPP3 PLPP2 | Choline metabolism in cancer |
| KEGG:04072 | 0.00350714576187 | 0.666666666667 | PLPP3 PLPP2 | Phospholipase D signaling pathway |
| REAC:R-HSA-1660661 | 0.00375073705264 | 0.666666666667 | PLPP3 PLPP2 | Sphingolipid de novo biosynthesis |
| REAC:R-HSA-428157 | 0.0180259784934 | 0.666666666667 | PLPP3 PLPP2 | Sphingolipid metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PLPPR1 | PLPP3 | 0.29 | 0.492 | bioplex (PLPPR1) bioplex_WMM |
| PLPP3 | PLPP2 | 0.246 | 0.47 | bioplex (PLPP2) bioplex_WMM |
Images
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Complex HuMAP2_05688 has an average edge precision of 0.481 which is ranked 2626 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PLPPR1 | HuMAP2_01946 HuMAP2_02780 HuMAP2_02919 HuMAP2_03422 HuMAP2_05193 HuMAP2_05688 |
| PLPP3 | HuMAP2_01946 HuMAP2_02780 HuMAP2_02919 HuMAP2_03422 HuMAP2_05193 HuMAP2_05688 |
| PLPP2 | HuMAP2_01946 HuMAP2_02919 HuMAP2_03422 HuMAP2_05193 HuMAP2_05688 |