hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_05691

Confidence: Medium

Genename	Protein Name	Links
RPSA	40S ribosomal protein SA (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (67 kDa laminin receptor) (67LR) (Colon carcinoma laminin-binding protein) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (Multidrug resistance-associated protein MGr1-Ag) (NEM/1CHD4) (Small ribosomal subunit protein uS2)	UniProt NCBI
CDR2L	Cerebellar degeneration-related protein 2-like (Paraneoplastic 62 kDa antigen)	UniProt NCBI
RPSAP58		NCBI
RPS21	40S ribosomal protein S21 (Small ribosomal subunit protein eS21)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:338	0.001558516625	0.666666666667	RPS21 RPSA	40S ribosomal subunit, cytoplasmic
CORUM:305	0.00176951183951	0.666666666667	RPS21 RPSA	40S ribosomal subunit, cytoplasmic
WP:WP477	0.00357470816736	0.666666666667	RPS21 RPSA	Cytoplasmic Ribosomal Proteins
KEGG:03010	0.00373360278335	0.666666666667	RPS21 RPSA	Ribosome
REAC:R-HSA-72695	0.008858224502	0.666666666667	RPS21 RPSA	Formation of the ternary complex, and subsequently, the 43S complex
CORUM:306	0.0103042111837	0.666666666667	RPS21 RPSA	Ribosome, cytoplasmic
REAC:R-HSA-72649	0.011426592715	0.666666666667	RPS21 RPSA	Translation initiation complex formation
REAC:R-HSA-72702	0.011426592715	0.666666666667	RPS21 RPSA	Ribosomal scanning and start codon recognition
REAC:R-HSA-72662	0.0118200826291	0.666666666667	RPS21 RPSA	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REAC:R-HSA-156902	0.0255313065434	0.666666666667	RPS21 RPSA	Peptide chain elongation
REAC:R-HSA-192823	0.0255313065434	0.666666666667	RPS21 RPSA	Viral mRNA Translation
REAC:R-HSA-72764	0.0279140119136	0.666666666667	RPS21 RPSA	Eukaryotic Translation Termination
REAC:R-HSA-2408557	0.0279140119136	0.666666666667	RPS21 RPSA	Selenocysteine synthesis
REAC:R-HSA-156842	0.0279140119136	0.666666666667	RPS21 RPSA	Eukaryotic Translation Elongation
REAC:R-HSA-975956	0.0291450496188	0.666666666667	RPS21 RPSA	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
REAC:R-HSA-72689	0.0329968164925	0.666666666667	RPS21 RPSA	Formation of a pool of free 40S subunits
REAC:R-HSA-156827	0.0399448421955	0.666666666667	RPS21 RPSA	L13a-mediated translational silencing of Ceruloplasmin expression
REAC:R-HSA-1799339	0.0406759452204	0.666666666667	RPS21 RPSA	SRP-dependent cotranslational protein targeting to membrane
REAC:R-HSA-72706	0.0406759452204	0.666666666667	RPS21 RPSA	GTP hydrolysis and joining of the 60S ribosomal subunit
REAC:R-HSA-975957	0.0421579398286	0.666666666667	RPS21 RPSA	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
REAC:R-HSA-927802	0.0421579398286	0.666666666667	RPS21 RPSA	Nonsense-Mediated Decay (NMD)
REAC:R-HSA-2408522	0.0429088296136	0.666666666667	RPS21 RPSA	Selenoamino acid metabolism
REAC:R-HSA-72737	0.0459783176444	0.666666666667	RPS21 RPSA	Cap-dependent Translation Initiation
REAC:R-HSA-72613	0.0459783176444	0.666666666667	RPS21 RPSA	Eukaryotic Translation Initiation

Edges

Protein 1	Protein 2	Score	Precision	Evidence
RPSA	RPSAP58	1.0	0.949	bioplex (RPSA) bioplex_WMM
CDR2L	RPSA	0.045	0.291	bioplex (RPSA) bioplex_WMM youn_WMM
RPSA	RPS21	0.03	0.232	hein_WMM bioplex (RPSA) bioplex_WMM youn_WMM boldt_WMM
CDR2L	RPSAP58	0.009	0.102	bioplex_WMM WMM_only
RPSAP58	RPS21	0.009	0.095	bioplex_WMM WMM_only
CDR2L	RPS21	0.008	0.085	bioplex_WMM WMM_only

Images

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Complex HuMAP2_05691 has an average edge precision of 0.292 which is ranked 4721 out of all 6965 complexes.

Related Complexes

Genename	Complexes
RPSA	HuMAP2_02207 HuMAP2_03749 HuMAP2_04445 HuMAP2_05691
CDR2L	HuMAP2_00934 HuMAP2_01006 HuMAP2_02031 HuMAP2_03214 HuMAP2_04445 HuMAP2_05313 HuMAP2_05691
RPSAP58	HuMAP2_04445 HuMAP2_05691
RPS21	HuMAP2_05691

hu.MAP 2.0: Complex View

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Complex: HuMAP2_05691