hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05710
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NOB1 | RNA-binding protein NOB1 (Phosphorylation regulatory protein HP-10) (Protein ART-4) | UniProt NCBI |
| HLA-DPA1 | HLA class II histocompatibility antigen, DP alpha 1 chain (DP(W3)) (DP(W4)) (HLA-SB alpha chain) (MHC class II DP3-alpha) (MHC class II DPA1) | UniProt NCBI |
| ATP13A2 | Cation-transporting ATPase 13A2 (EC 3.6.3.-) | UniProt NCBI |
| PNO1 | RNA-binding protein PNO1 | UniProt NCBI |
| APOE | Apolipoprotein E (Apo-E) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004311 | 0.0138999712057 | 0.4 | HLA-DPA1 APOE | Abnormal macrophage morphology |
| HP:0001681 | 0.0188011826397 | 0.4 | HLA-DPA1 APOE | Angina pectoris |
| HP:0002113 | 0.0291468055875 | 0.4 | HLA-DPA1 APOE | Pulmonary infiltrates |
| HP:0100820 | 0.0478196851342 | 0.4 | HLA-DPA1 APOE | Glomerulopathy |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NOB1 | HLA-DPA1 | 0.242 | 0.468 | bioplex (HLA-DPA1) bioplex_WMM |
| HLA-DPA1 | ATP13A2 | 0.201 | 0.45 | bioplex (HLA-DPA1) bioplex_WMM |
| NOB1 | PNO1 | 0.059 | 0.328 | hein_WMM bioplex (NOB1,PNO1) bioplex_WMM youn_WMM gupta_WMM fraction |
| APOE | HLA-DPA1 | 0.051 | 0.299 | bioplex (HLA-DPA1) bioplex_WMM |
| APOE | NOB1 | 0.007 | 0.018 | bioplex_WMM WMM_only |
| APOE | ATP13A2 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| NOB1 | ATP13A2 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| PNO1 | ATP13A2 | 0.006 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05710 has an average edge precision of 0.197 which is ranked 6222 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NOB1 | HuMAP2_02559 HuMAP2_03347 HuMAP2_03680 HuMAP2_05710 HuMAP2_06629 HuMAP2_06766 |
| HLA-DPA1 | HuMAP2_03680 HuMAP2_05710 |
| ATP13A2 | HuMAP2_03680 HuMAP2_05710 |
| PNO1 | HuMAP2_02559 HuMAP2_03347 HuMAP2_05710 HuMAP2_06766 |
| APOE | HuMAP2_01915 HuMAP2_02283 HuMAP2_03680 HuMAP2_05710 |