hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05718
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PADI4 | Protein-arginine deiminase type-4 (EC 3.5.3.15) (HL-60 PAD) (Peptidylarginine deiminase IV) (Protein-arginine deiminase type IV) | UniProt NCBI |
| PADI3 | Protein-arginine deiminase type-3 (EC 3.5.3.15) (Peptidylarginine deiminase III) (Protein-arginine deiminase type III) | UniProt NCBI |
| PADI1 | Protein-arginine deiminase type-1 (EC 3.5.3.15) (Peptidylarginine deiminase I) (Protein-arginine deiminase type I) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004668 | 9.08185760231e-08 | 1.0 | PADI3 PADI1 PADI4 | protein-arginine deiminase activity |
| GO:0018101 | 9.08185760231e-08 | 1.0 | PADI3 PADI1 PADI4 | protein citrullination |
| GO:0036414 | 9.08185760231e-08 | 1.0 | PADI3 PADI1 PADI4 | histone citrullination |
| GO:0016813 | 5.08584025729e-06 | 1.0 | PADI3 PADI1 PADI4 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
| GO:0018195 | 7.41079580349e-05 | 1.0 | PADI3 PADI1 PADI4 | peptidyl-arginine modification |
| REAC:R-HSA-3247509 | 0.00144234915262 | 1.0 | PADI3 PADI1 PADI4 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.00144234915262 | 1.0 | PADI3 PADI1 PADI4 | Chromatin organization |
| GO:0016810 | 0.0142448028307 | 1.0 | PADI3 PADI1 PADI4 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PADI3 | PADI4 | 0.98 | 0.896 | bioplex (PADI3,PADI4) bioplex_WMM |
| PADI3 | PADI1 | 0.025 | 0.215 | bioplex (PADI3) bioplex_WMM |
| PADI4 | PADI1 | 0.008 | 0.085 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05718 has an average edge precision of 0.399 which is ranked 3343 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PADI4 | HuMAP2_03849 HuMAP2_04192 HuMAP2_05718 |
| PADI3 | HuMAP2_03849 HuMAP2_04192 HuMAP2_05718 |
| PADI1 | HuMAP2_04179 HuMAP2_05718 |