hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05725
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| AP1B1 | AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) | UniProt NCBI |
| CTPS1 | CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1) | UniProt NCBI |
| GMIP | GEM-interacting protein (GMIP) | UniProt NCBI |
| TIGD3 | Tigger transposable element-derived protein 3 | UniProt NCBI |
| SNX3 | Sorting nexin-3 (Protein SDP3) | UniProt NCBI |
| CTPS2 | CTP synthase 2 (EC 6.3.4.2) (CTP synthetase 2) (UTP--ammonia ligase 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003883 | 0.00676235117068 | 0.333333333333 | CTPS1 CTPS2 | CTP synthase activity |
| GO:0006241 | 0.00676235117068 | 0.333333333333 | CTPS1 CTPS2 | CTP biosynthetic process |
| GO:0046036 | 0.00676235117068 | 0.333333333333 | CTPS1 CTPS2 | CTP metabolic process |
| KEGG:00240 | 0.0076045655811 | 0.333333333333 | CTPS1 CTPS2 | Pyrimidine metabolism |
| REAC:R-HSA-499943 | 0.00774747127227 | 0.333333333333 | CTPS1 CTPS2 | Interconversion of nucleotide di- and triphosphates |
| WP:WP4022 | 0.0169827894955 | 0.333333333333 | CTPS1 CTPS2 | Pyrimidine metabolism |
| GO:0097268 | 0.020283420769 | 0.333333333333 | CTPS1 CTPS2 | cytoophidium |
| GO:0009209 | 0.020283420769 | 0.333333333333 | CTPS1 CTPS2 | pyrimidine ribonucleoside triphosphate biosynthetic process |
| GO:0009148 | 0.0405595771497 | 0.333333333333 | CTPS1 CTPS2 | pyrimidine nucleoside triphosphate biosynthetic process |
| GO:0009208 | 0.0405595771497 | 0.333333333333 | CTPS1 CTPS2 | pyrimidine ribonucleoside triphosphate metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CTPS1 | AP1B1 | 0.138 | 0.406 | gupta_WMM fraction treiber_WMM |
| TIGD3 | CTPS2 | 0.13 | 0.401 | bioplex (TIGD3) bioplex_WMM |
| CTPS2 | SNX3 | 0.1 | 0.361 | hein_WMM hein (SNX3) |
| CTPS2 | AP1B1 | 0.089 | 0.355 | fraction |
| CTPS1 | SNX3 | 0.086 | 0.351 | hein_WMM bioplex_WMM hein (SNX3) gupta_WMM |
| CTPS1 | CTPS2 | 0.069 | 0.348 | hein_WMM bioplex (CTPS2) bioplex_WMM gupta_WMM |
| GMIP | AP1B1 | 0.047 | 0.293 | fraction |
| CTPS1 | TIGD3 | 0.022 | 0.207 | bioplex (TIGD3) bioplex_WMM |
| AP1B1 | SNX3 | 0.007 | 0.005 | gupta_WMM WMM_only |
Images
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Complex HuMAP2_05725 has an average edge precision of 0.303 which is ranked 4536 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| AP1B1 | HuMAP2_02368 HuMAP2_05170 HuMAP2_05725 |
| CTPS1 | HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725 |
| GMIP | HuMAP2_02368 HuMAP2_05170 HuMAP2_05725 |
| TIGD3 | HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725 |
| SNX3 | HuMAP2_02731 HuMAP2_05725 |
| CTPS2 | HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725 |