hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05734
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PABPC1 | Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) | UniProt NCBI |
| PABPC4 | Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP) | UniProt NCBI |
| LARP1 | La-related protein 1 (La ribonucleoprotein domain family member 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7563 | 1.00675659188e-05 | 0.666666666667 | PABPC1 LARP1 | LARP1-PABPC1-RYDEN complex |
| KEGG:03018 | 0.00127210962765 | 0.666666666667 | PABPC1 PABPC4 | RNA degradation |
| KEGG:03015 | 0.0017077231529 | 0.666666666667 | PABPC1 PABPC4 | mRNA surveillance pathway |
| GO:0010494 | 0.00238262534197 | 1.0 | PABPC1 PABPC4 LARP1 | cytoplasmic stress granule |
| KEGG:03013 | 0.00517225695918 | 0.666666666667 | PABPC1 PABPC4 | RNA transport |
| GO:0003730 | 0.00588722337212 | 1.0 | PABPC1 PABPC4 LARP1 | mRNA 3'-UTR binding |
| GO:0008494 | 0.0486736709081 | 0.666666666667 | PABPC1 LARP1 | translation activator activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PABPC1 | PABPC4 | 1.0 | 0.949 | hein_WMM youn (PABPC1) bioplex_WMM youn_WMM hein (PABPC1) gupta_WMM fraction boldt_WMM treiber_WMM |
| LARP1 | PABPC1 | 1.0 | 0.949 | hein_WMM youn (PABPC1) bioplex_WMM boldt hein (PABPC1) gupta_WMM fraction boldt_WMM treiber_WMM |
| LARP1 | PABPC4 | 0.849 | 0.79 | hein_WMM bioplex_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_05734 has an average edge precision of 0.896 which is ranked 595 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PABPC1 | HuMAP2_01130 HuMAP2_04393 HuMAP2_05559 HuMAP2_05734 HuMAP2_06735 |
| PABPC4 | HuMAP2_04393 HuMAP2_04632 HuMAP2_05552 HuMAP2_05559 HuMAP2_05734 HuMAP2_05864 |
| LARP1 | HuMAP2_00428 HuMAP2_04560 HuMAP2_04632 HuMAP2_05552 HuMAP2_05734 |