hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05736
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KNTC1 | Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod) | UniProt NCBI |
| C19orf25 | UPF0449 protein C19orf25 | UniProt NCBI |
| ZW10 | Centromere/kinetochore protein zw10 homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7541 | 1.00675659188e-05 | 0.666666666667 | ZW10 KNTC1 | KNTC1-ZW10-ZWILCH complex |
| GO:1990423 | 0.00405722906526 | 0.666666666667 | ZW10 KNTC1 | RZZ complex |
| REAC:R-HSA-141444 | 0.0279140119136 | 0.666666666667 | ZW10 KNTC1 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141424 | 0.0279140119136 | 0.666666666667 | ZW10 KNTC1 | Amplification of signal from the kinetochores |
| GO:0005828 | 0.0283955176165 | 0.666666666667 | ZW10 KNTC1 | kinetochore microtubule |
| REAC:R-HSA-69618 | 0.037791121028 | 0.666666666667 | ZW10 KNTC1 | Mitotic Spindle Checkpoint |
| REAC:R-HSA-2500257 | 0.0475526064057 | 0.666666666667 | ZW10 KNTC1 | Resolution of Sister Chromatid Cohesion |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KNTC1 | ZW10 | 0.999 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (ZW10) Malo fraction boldt_WMM |
| C19orf25 | ZW10 | 0.7 | 0.722 | hein_WMM bioplex_WMM hein (ZW10) gupta_WMM |
| KNTC1 | C19orf25 | 0.008 | 0.034 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05736 has an average edge precision of 0.568 which is ranked 2090 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KNTC1 | HuMAP2_00483 HuMAP2_05736 HuMAP2_06258 HuMAP2_06333 |
| C19orf25 | HuMAP2_00854 HuMAP2_02979 HuMAP2_05736 HuMAP2_06258 HuMAP2_06333 |
| ZW10 | HuMAP2_00854 HuMAP2_02979 HuMAP2_05736 HuMAP2_06258 HuMAP2_06333 |