hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05738
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CCDC47 | Coiled-coil domain-containing protein 47 | UniProt NCBI |
| TIMM17B | Mitochondrial import inner membrane translocase subunit Tim17-B | UniProt NCBI |
| SLC25A22 | Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22) | UniProt NCBI |
| SLC25A18 | Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-428643 | 0.000211071833435 | 0.5 | SLC25A22 SLC25A18 | Organic anion transporters |
| GO:0043490 | 0.0162267366884 | 0.5 | SLC25A22 SLC25A18 | malate-aspartate shuttle |
| GO:0015183 | 0.0270421395626 | 0.5 | SLC25A22 SLC25A18 | L-aspartate transmembrane transporter activity |
| REAC:R-HSA-425393 | 0.0307679435258 | 0.5 | SLC25A22 SLC25A18 | Transport of inorganic cations/anions and amino acids/oligopeptides |
| GO:0015810 | 0.0405595771497 | 0.5 | SLC25A22 SLC25A18 | aspartate transmembrane transport |
| GO:1990542 | 0.0410761885593 | 0.75 | SLC25A22 TIMM17B SLC25A18 | mitochondrial transmembrane transport |
| CORUM:6458 | 0.0499140284799 | 0.25 | TIMM17B | TIM17B-TIM23 complex, mitochondrial |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SLC25A22 | SLC25A18 | 0.983 | 0.899 | bioplex (SLC25A22) bioplex_WMM |
| SLC25A22 | CCDC47 | 0.044 | 0.279 | bioplex (SLC25A22) bioplex_WMM boldt fraction boldt_WMM |
| CCDC47 | TIMM17B | 0.021 | 0.191 | bioplex_WMM boldt fraction boldt_WMM |
| SLC25A22 | TIMM17B | 0.007 | 0.005 | bioplex_WMM boldt boldt_WMM |
| SLC25A18 | CCDC47 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| SLC25A18 | TIMM17B | 0.007 | 0.0 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05738 has an average edge precision of 0.229 which is ranked 5715 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CCDC47 | HuMAP2_05470 HuMAP2_05738 HuMAP2_06765 |
| TIMM17B | HuMAP2_05470 HuMAP2_05738 |
| SLC25A22 | HuMAP2_05312 HuMAP2_05470 HuMAP2_05738 HuMAP2_06765 |
| SLC25A18 | HuMAP2_05312 HuMAP2_05470 HuMAP2_05738 HuMAP2_06765 |