hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05766
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GPN1 | GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1) | UniProt NCBI |
| MYZAP | Myocardial zonula adherens protein (GRINL1A upstream protein) (Gup) | UniProt NCBI |
| GPN3 | GPN-loop GTPase 3 (ATP-binding domain 1 family member C) | UniProt NCBI |
| RPRD1B | Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor) | UniProt NCBI |
| POLR2C | DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31) | UniProt NCBI |
| POLR2A | DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48) | UniProt NCBI |
| POLR2G | DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19) | UniProt NCBI |
| POLR2F | DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide) (RPABC14.4) (RPB14.4) (RPB6 homolog) (RPC15) | UniProt NCBI |
| POLR2J | DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit) | UniProt NCBI |
| RPAP2 | Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2) | UniProt NCBI |
| POLR2D | DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) (RNA polymerase II 16 kDa subunit) (RPB16) | UniProt NCBI |
| POLR2B | DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) | UniProt NCBI |
| POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide) (RPB17) (RPB8 homolog) (hRPB8) | UniProt NCBI |
| POLR2E | DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4) | UniProt NCBI |
| POLR2I | DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5) | UniProt NCBI |
| POLR2L | DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:104 | 1.21481838642e-32 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA polymerase II core complex |
| CORUM:2686 | 7.89388763437e-32 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | BRCA1-core RNA polymerase II complex |
| CORUM:2685 | 1.25095436368e-29 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA polymerase II (RNAPII) |
| GO:0005665 | 8.52539864512e-29 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA polymerase II, core complex |
| REAC:R-HSA-8851708 | 4.48144265971e-28 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signaling by FGFR2 IIIa TM |
| CORUM:103 | 2.5176418106e-27 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA polymerase II holoenzyme complex |
| CORUM:2825 | 7.78789805718e-27 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | BRCA1-RNA polymerase II complex |
| REAC:R-HSA-167242 | 8.00692658417e-27 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Abortive elongation of HIV-1 transcript in the absence of Tat |
| REAC:R-HSA-203927 | 1.47774628014e-26 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | MicroRNA (miRNA) biogenesis |
| REAC:R-HSA-1839126 | 2.63801936153e-26 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | FGFR2 mutant receptor activation |
| REAC:R-HSA-6803529 | 4.5711575553e-26 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | FGFR2 alternative splicing |
| REAC:R-HSA-6807505 | 5.55321546631e-26 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | RNA polymerase II transcribes snRNA genes |
| KEGG:03020 | 6.23248959581e-26 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA polymerase |
| REAC:R-HSA-167160 | 7.71145070721e-26 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Pol II CTD phosphorylation and interaction with CE during HIV infection |
| REAC:R-HSA-77075 | 7.71145070721e-26 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Pol II CTD phosphorylation and interaction with CE |
| REAC:R-HSA-72086 | 2.04504512442e-25 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | mRNA Capping |
| REAC:R-HSA-5601884 | 2.04504512442e-25 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | PIWI-interacting RNA (piRNA) biogenesis |
| REAC:R-HSA-167243 | 7.61958255938e-25 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Tat-mediated HIV elongation arrest and recovery |
| REAC:R-HSA-167238 | 7.61958255938e-25 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Pausing and recovery of Tat-mediated HIV elongation |
| REAC:R-HSA-113418 | 1.14258496458e-24 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Formation of the Early Elongation Complex |
| REAC:R-HSA-167158 | 1.14258496458e-24 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Formation of the HIV-1 Early Elongation Complex |
| REAC:R-HSA-167290 | 1.68851780502e-24 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Pausing and recovery of HIV elongation |
| REAC:R-HSA-167287 | 1.68851780502e-24 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | HIV elongation arrest and recovery |
| REAC:R-HSA-5655253 | 1.68851780502e-24 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signaling by FGFR2 in disease |
| GO:0042795 | 4.63771889826e-24 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | snRNA transcription by RNA polymerase II |
| GO:0009301 | 5.67614109266e-24 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | snRNA transcription |
| GO:0016591 | 6.9255148915e-24 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | RNA polymerase II, holoenzyme |
| REAC:R-HSA-168325 | 1.36187704683e-23 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Viral Messenger RNA Synthesis |
| REAC:R-HSA-167246 | 4.51241749449e-23 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Tat-mediated elongation of the HIV-1 transcript |
| REAC:R-HSA-167169 | 4.51241749449e-23 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | HIV Transcription Elongation |
| REAC:R-HSA-167200 | 4.51241749449e-23 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Formation of HIV-1 elongation complex containing HIV-1 Tat |
| REAC:R-HSA-167152 | 7.84448778188e-23 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Formation of HIV elongation complex in the absence of HIV Tat |
| REAC:R-HSA-167162 | 1.02382540605e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II HIV Promoter Escape |
| REAC:R-HSA-76042 | 1.02382540605e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II Transcription Initiation And Promoter Clearance |
| REAC:R-HSA-73779 | 1.02382540605e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| REAC:R-HSA-167161 | 1.02382540605e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | HIV Transcription Initiation |
| REAC:R-HSA-75953 | 1.02382540605e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II Transcription Initiation |
| REAC:R-HSA-73776 | 1.02382540605e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II Promoter Escape |
| GO:0009452 | 1.40200319093e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | 7-methylguanosine RNA capping |
| GO:0006370 | 1.40200319093e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | 7-methylguanosine mRNA capping |
| GO:0036260 | 2.10235633483e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA capping |
| REAC:R-HSA-72165 | 3.54521532853e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | mRNA Splicing - Minor Pathway |
| GO:0055029 | 3.92451362112e-22 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | nuclear DNA-directed RNA polymerase complex |
| REAC:R-HSA-1226099 | 4.47234299791e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signaling by FGFR in disease |
| REAC:R-HSA-6781823 | 4.47234299791e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Formation of TC-NER Pre-Incision Complex |
| GO:0000428 | 4.53102608851e-22 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | DNA-directed RNA polymerase complex |
| GO:0030880 | 6.90837643906e-22 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | RNA polymerase complex |
| GO:0098781 | 7.92743974029e-22 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | ncRNA transcription |
| GO:0003899 | 9.27618211191e-22 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | DNA-directed 5'-3' RNA polymerase activity |
| REAC:R-HSA-5654738 | 1.33389763526e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signaling by FGFR2 |
| REAC:R-HSA-75955 | 1.63907616348e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II Transcription Elongation |
| REAC:R-HSA-112382 | 1.63907616348e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Formation of RNA Pol II elongation complex |
| GO:0050434 | 2.50585376618e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | positive regulation of viral transcription |
| GO:0034062 | 2.50585376618e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | 5'-3' RNA polymerase activity |
| GO:0097747 | 2.50585376618e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA polymerase activity |
| GO:0035019 | 2.50585376618e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | somatic stem cell population maintenance |
| REAC:R-HSA-6796648 | 2.97394665124e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | TP53 Regulates Transcription of DNA Repair Genes |
| REAC:R-HSA-6782210 | 4.3481661078e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Gap-filling DNA repair synthesis and ligation in TC-NER |
| REAC:R-HSA-6782135 | 5.23228669783e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Dual incision in TC-NER |
| REAC:R-HSA-190236 | 7.50742753472e-21 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signaling by FGFR |
| REAC:R-HSA-167172 | 1.4940410214e-20 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Transcription of the HIV genome |
| REAC:R-HSA-6781827 | 4.52893137062e-20 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| REAC:R-HSA-674695 | 8.14254250199e-20 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II Pre-transcription Events |
| GO:0046782 | 3.01590014081e-19 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of viral transcription |
| GO:0001055 | 4.82605584078e-19 | 0.5 | POLR2A POLR2E POLR2C POLR2L POLR2F POLR2H POLR2B POLR2J | RNA polymerase II activity |
| REAC:R-HSA-5578749 | 1.02957168284e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Transcriptional regulation by small RNAs |
| REAC:R-HSA-5696398 | 2.45779894853e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Nucleotide Excision Repair |
| WP:WP405 | 3.12530108398e-18 | 0.5625 | POLR2A POLR2C POLR2G POLR2I POLR2J POLR2E POLR2H POLR2B POLR2F | Eukaryotic Transcription Initiation |
| GO:0006283 | 3.81808572117e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | transcription-coupled nucleotide-excision repair |
| REAC:R-HSA-5617472 | 4.09546754131e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Activation of anterior HOX genes in hindbrain development during early embryogenesis |
| REAC:R-HSA-5619507 | 4.09546754131e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Activation of HOX genes during differentiation |
| WP:WP4022 | 5.97306678652e-18 | 0.625 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2E POLR2H POLR2B POLR2J | Pyrimidine metabolism |
| GO:0008543 | 8.33323372193e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | fibroblast growth factor receptor signaling pathway |
| GO:0019827 | 9.67826340202e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | stem cell population maintenance |
| GO:0006368 | 9.67826340202e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | transcription elongation from RNA polymerase II promoter |
| GO:0098727 | 9.67826340202e-18 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | maintenance of cell number |
| REAC:R-HSA-168273 | 1.66502259324e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Influenza Viral RNA Transcription and Replication |
| REAC:R-HSA-211000 | 1.98166064321e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Gene Silencing by RNA |
| REAC:R-HSA-162599 | 2.1596648187e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Late Phase of HIV Life Cycle |
| REAC:R-HSA-168255 | 3.28759703934e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Influenza Life Cycle |
| GO:0061695 | 3.59945611244e-17 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | transferase complex, transferring phosphorus-containing groups |
| REAC:R-HSA-9018519 | 4.19848981378e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Estrogen-dependent gene expression |
| GO:0044344 | 5.04957461283e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cellular response to fibroblast growth factor stimulus |
| REAC:R-HSA-162587 | 6.23722268731e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | HIV Life Cycle |
| GO:0071774 | 6.50066630279e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | response to fibroblast growth factor |
| REAC:R-HSA-168254 | 7.27848694083e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Influenza Infection |
| GO:0048524 | 9.395090378e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | positive regulation of viral process |
| KEGG:05016 | 9.96778908016e-17 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Huntington disease |
| GO:0060964 | 2.64686705755e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of gene silencing by miRNA |
| GO:0006289 | 2.64686705755e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | nucleotide-excision repair |
| GO:0006354 | 2.64686705755e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | DNA-templated transcription, elongation |
| GO:0060966 | 3.28971201951e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of gene silencing by RNA |
| GO:0060147 | 3.28971201951e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of posttranscriptional gene silencing |
| GO:0016779 | 5.01825346932e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | nucleotidyltransferase activity |
| REAC:R-HSA-72163 | 5.8637091492e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 9.61872452871e-16 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | mRNA Splicing |
| REAC:R-HSA-8939211 | 2.71474157206e-15 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | ESR-mediated signaling |
| GO:0035195 | 6.56699135695e-15 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | gene silencing by miRNA |
| REAC:R-HSA-162906 | 7.36027509851e-15 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | HIV Infection |
| GO:0060968 | 9.0660987622e-15 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of gene silencing |
| REAC:R-HSA-72203 | 1.32221951064e-14 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0035194 | 1.33924159711e-14 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | posttranscriptional gene silencing by RNA |
| GO:0016441 | 1.44554375304e-14 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | posttranscriptional gene silencing |
| REAC:R-HSA-9006931 | 2.01134752147e-14 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signaling by Nuclear Receptors |
| GO:0031047 | 3.01694546476e-14 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | gene silencing by RNA |
| GO:0006367 | 6.42403366821e-14 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | transcription initiation from RNA polymerase II promoter |
| GO:0019083 | 6.8635513302e-14 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | viral transcription |
| GO:0050792 | 1.38574784964e-13 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of viral process |
| GO:0019080 | 1.99608238424e-13 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | viral gene expression |
| GO:0043903 | 3.01030948796e-13 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of symbiosis, encompassing mutualism through parasitism |
| REAC:R-HSA-73894 | 4.2401128912e-13 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | DNA Repair |
| GO:0006352 | 6.55310026704e-13 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | DNA-templated transcription, initiation |
| REAC:R-HSA-5663202 | 7.26405713278e-13 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Diseases of signal transduction |
| REAC:R-HSA-3700989 | 1.036115538e-12 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Transcriptional Regulation by TP53 |
| REAC:R-HSA-5663205 | 1.41690396969e-12 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Infectious disease |
| GO:0016458 | 1.82235167462e-12 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | gene silencing |
| REAC:R-HSA-9006934 | 5.82969536813e-12 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signaling by Receptor Tyrosine Kinases |
| GO:0006397 | 9.30276561306e-12 | 0.75 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J RPRD1B POLR2E POLR2H POLR2B POLR2F | mRNA processing |
| GO:0040029 | 2.83608179484e-11 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of gene expression, epigenetic |
| GO:0140098 | 4.93464972448e-11 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | catalytic activity, acting on RNA |
| GO:0000377 | 5.69339733891e-11 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 5.69339733891e-11 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | mRNA splicing, via spliceosome |
| GO:0000375 | 6.33029863613e-11 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA splicing, via transesterification reactions |
| GO:1990234 | 1.18234596381e-10 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | transferase complex |
| GO:0008380 | 3.75172180596e-10 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | RNA splicing |
| REAC:R-HSA-73857 | 4.1082029909e-10 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | RNA Polymerase II Transcription |
| REAC:R-HSA-8953854 | 1.01245648222e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Metabolism of RNA |
| GO:0071363 | 1.22697036739e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cellular response to growth factor stimulus |
| GO:0043902 | 1.55630461824e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | positive regulation of multi-organism process |
| REAC:R-HSA-74160 | 1.66486703773e-09 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | Gene expression (Transcription) |
| GO:0070848 | 1.81838538443e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | response to growth factor |
| GO:0016032 | 2.2300225939e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | viral process |
| GO:0006281 | 3.65391645952e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | DNA repair |
| GO:0044451 | 4.07902020748e-09 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | nucleoplasm part |
| GO:0044403 | 6.42235174462e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | symbiotic process |
| GO:0010608 | 8.42334351902e-09 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | posttranscriptional regulation of gene expression |
| GO:0016071 | 1.00991679083e-08 | 0.75 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J RPRD1B POLR2E POLR2H POLR2B POLR2F | mRNA metabolic process |
| GO:0044419 | 1.17122363927e-08 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | interspecies interaction between organisms |
| GO:0007169 | 1.33256202855e-08 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | transmembrane receptor protein tyrosine kinase signaling pathway |
| GO:0006396 | 2.60057642907e-08 | 0.75 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J RPRD1B POLR2E POLR2H POLR2B POLR2F | RNA processing |
| REAC:R-HSA-1266738 | 4.25183835924e-08 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Developmental Biology |
| GO:0043900 | 5.30558492074e-08 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | regulation of multi-organism process |
| REAC:R-HSA-1643685 | 5.86753905968e-08 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Disease |
| GO:1902494 | 1.19628083267e-07 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | catalytic complex |
| REAC:R-HSA-212436 | 1.47319533012e-07 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Generic Transcription Pathway |
| GO:0007167 | 4.70169589215e-07 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | enzyme linked receptor protein signaling pathway |
| GO:0006259 | 4.7740448844e-07 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | DNA metabolic process |
| GO:0006974 | 4.84740008991e-07 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cellular response to DNA damage stimulus |
| REAC:R-HSA-73780 | 7.31751761852e-07 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Chain Elongation |
| GO:0016772 | 1.21475300228e-06 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | transferase activity, transferring phosphorus-containing groups |
| REAC:R-HSA-73980 | 2.11071600975e-06 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Transcription Termination |
| GO:0006366 | 3.32191004573e-06 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | transcription by RNA polymerase II |
| GO:0071495 | 3.93109511033e-06 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cellular response to endogenous stimulus |
| REAC:R-HSA-76066 | 4.17250940344e-06 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| REAC:R-HSA-76071 | 4.86478705295e-06 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| REAC:R-HSA-76061 | 4.86478705295e-06 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Transcription Initiation From Type 1 Promoter |
| REAC:R-HSA-73863 | 7.46151083698e-06 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase I Transcription Termination |
| GO:0009719 | 1.04350041648e-05 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | response to endogenous stimulus |
| REAC:R-HSA-76046 | 1.39235365504e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Transcription Initiation |
| KEGG:04623 | 1.9089520901e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | Cytosolic DNA-sensing pathway |
| REAC:R-HSA-74158 | 2.38603256754e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Transcription |
| REAC:R-HSA-749476 | 2.38603256754e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase III Abortive And Retractive Initiation |
| GO:0005736 | 3.1562189528e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA polymerase I complex |
| GO:0001054 | 3.1562189528e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA polymerase I activity |
| REAC:R-HSA-73762 | 4.18622645724e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase I Transcription Initiation |
| WP:WP4655 | 5.43812303479e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | Cytosolic DNA-sensing pathway |
| GO:0001056 | 8.01847812953e-05 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA polymerase III activity |
| REAC:R-HSA-162582 | 0.000128770636439 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | Signal Transduction |
| GO:0005666 | 0.000134642324181 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA polymerase III complex |
| REAC:R-HSA-1834949 | 0.000138365282494 | 0.25 | POLR2H POLR2L POLR2F POLR2E | Cytosolic sensors of pathogen-associated DNA |
| CORUM:2812 | 0.000150180288233 | 0.125 | POLR2C POLR2B | RPAP1-RPB2-RPB3 complex |
| GO:0006351 | 0.000417698397092 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | transcription, DNA-templated |
| GO:0097659 | 0.00043174314231 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | nucleic acid-templated transcription |
| GO:0032774 | 0.000446219422111 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | RNA biosynthetic process |
| GO:0006353 | 0.000515390609573 | 0.3125 | POLR2A POLR2L POLR2F POLR2E POLR2H | DNA-templated transcription, termination |
| REAC:R-HSA-5250924 | 0.000557707834651 | 0.25 | POLR2H POLR2L POLR2F POLR2E | B-WICH complex positively regulates rRNA expression |
| REAC:R-HSA-73772 | 0.000583270516642 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase I Promoter Escape |
| GO:0010629 | 0.000758124320526 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | negative regulation of gene expression |
| GO:0006362 | 0.00103767023532 | 0.25 | POLR2H POLR2L POLR2F POLR2E | transcription elongation from RNA polymerase I promoter |
| REAC:R-HSA-5250913 | 0.00104014991294 | 0.25 | POLR2H POLR2L POLR2F POLR2E | Positive epigenetic regulation of rRNA expression |
| REAC:R-HSA-427413 | 0.00108064478647 | 0.25 | POLR2H POLR2L POLR2F POLR2E | NoRC negatively regulates rRNA expression |
| REAC:R-HSA-5250941 | 0.00120915751087 | 0.25 | POLR2H POLR2L POLR2F POLR2E | Negative epigenetic regulation of rRNA expression |
| REAC:R-HSA-73854 | 0.00125440895297 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase I Promoter Clearance |
| GO:0051704 | 0.00128934421214 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | multi-organism process |
| REAC:R-HSA-73864 | 0.00130090332921 | 0.25 | POLR2H POLR2L POLR2F POLR2E | RNA Polymerase I Transcription |
| GO:0006363 | 0.001372917994 | 0.25 | POLR2H POLR2L POLR2F POLR2E | termination of RNA polymerase I transcription |
| GO:0006361 | 0.00156803673361 | 0.25 | POLR2H POLR2L POLR2F POLR2E | transcription initiation from RNA polymerase I promoter |
| GO:0005654 | 0.00159504736508 | 0.875 | POLR2G GPN1 POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | nucleoplasm |
| GO:0033554 | 0.00219292817082 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cellular response to stress |
| GO:0034654 | 0.00257423462129 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | nucleobase-containing compound biosynthetic process |
| GO:0018130 | 0.00322410513827 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | heterocycle biosynthetic process |
| GO:0019438 | 0.00323911282623 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | aromatic compound biosynthetic process |
| REAC:R-HSA-212165 | 0.00399869750416 | 0.25 | POLR2H POLR2L POLR2F POLR2E | Epigenetic regulation of gene expression |
| CORUM:1155 | 0.00452416646481 | 0.125 | POLR2A POLR2B | Integrator-RNAPII complex |
| GO:0071310 | 0.00503173810834 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cellular response to organic substance |
| GO:1901362 | 0.00522234462791 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | organic cyclic compound biosynthetic process |
| CORUM:0000000 | 0.00579712999895 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | CORUM root |
| GO:0010468 | 0.00745214871106 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | regulation of gene expression |
| GO:0016740 | 0.0108209629207 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | transferase activity |
| CORUM:5233 | 0.0136359313761 | 0.125 | POLR2H POLR2L | TNF-alpha/NF-kappa B signaling complex 5 |
| GO:0010605 | 0.0193575390539 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | negative regulation of macromolecule metabolic process |
| GO:0045815 | 0.0195027889727 | 0.25 | POLR2H POLR2L POLR2F POLR2E | positive regulation of gene expression, epigenetic |
| GO:0006360 | 0.0195027889727 | 0.25 | POLR2H POLR2L POLR2F POLR2E | transcription by RNA polymerase I |
| GO:0031981 | 0.0202272263346 | 0.875 | POLR2G GPN1 POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | nuclear lumen |
| GO:0016070 | 0.020776041754 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | RNA metabolic process |
| GO:0007166 | 0.0217719584992 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cell surface receptor signaling pathway |
| GO:0010033 | 0.0233222824808 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | response to organic substance |
| GO:0032481 | 0.0271389543386 | 0.25 | POLR2H POLR2L POLR2F POLR2E | positive regulation of type I interferon production |
| GO:0044271 | 0.0292736133986 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | cellular nitrogen compound biosynthetic process |
| GO:0034645 | 0.0359489873606 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | cellular macromolecule biosynthetic process |
| GO:0070887 | 0.0428242907688 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | cellular response to chemical stimulus |
| GO:0044428 | 0.0476491419728 | 0.875 | POLR2G GPN1 POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | nuclear part |
| GO:0009892 | 0.0481877941109 | 0.6875 | POLR2G POLR2C POLR2A POLR2I POLR2L POLR2D POLR2J POLR2E POLR2H POLR2B POLR2F | negative regulation of metabolic process |
| GO:0009059 | 0.0487686989635 | 0.8125 | POLR2G POLR2C POLR2A POLR2I RPRD1B POLR2L POLR2D POLR2J RPAP2 POLR2E POLR2H POLR2B POLR2F | macromolecule biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| POLR2A | POLR2G | 1.0 | 0.949 | hein_WMM bioplex (POLR2G) bioplex_WMM youn_WMM hein (POLR2G) Malo fraction |
| POLR2C | POLR2G | 1.0 | 0.949 | hein_WMM bioplex (POLR2G) bioplex_WMM Guru youn_WMM hein (POLR2G) Malo fraction |
| POLR2D | POLR2G | 1.0 | 0.949 | hein_WMM bioplex (POLR2D,POLR2G) bioplex_WMM youn_WMM hein (POLR2G) Malo fraction |
| POLR2C | POLR2A | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| POLR2A | POLR2B | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| POLR2G | RPAP2 | 1.0 | 0.949 | hein_WMM bioplex (POLR2G) bioplex_WMM youn_WMM hein (POLR2G) |
| POLR2H | POLR2E | 1.0 | 0.949 | hein_WMM bioplex (POLR2E) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| POLR2C | POLR2B | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM Malo fraction boldt_WMM |
| POLR2D | POLR2A | 1.0 | 0.949 | hein_WMM bioplex (POLR2D) bioplex_WMM youn_WMM Malo fraction |
| POLR2G | POLR2I | 1.0 | 0.949 | hein_WMM bioplex (POLR2G) bioplex_WMM youn_WMM hein (POLR2G) |
| POLR2A | POLR2I | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo fraction |
| POLR2C | POLR2D | 1.0 | 0.949 | hein_WMM bioplex (POLR2D) bioplex_WMM youn_WMM Malo fraction |
| POLR2A | POLR2E | 1.0 | 0.949 | hein_WMM bioplex (POLR2E) bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| POLR2A | POLR2L | 1.0 | 0.949 | bioplex_WMM youn_WMM Malo fraction |
| POLR2I | POLR2L | 1.0 | 0.949 | bioplex_WMM youn_WMM Malo fraction |
| POLR2G | POLR2L | 1.0 | 0.949 | bioplex (POLR2G) bioplex_WMM youn_WMM Malo fraction |
| POLR2C | POLR2L | 1.0 | 0.949 | bioplex_WMM youn_WMM Malo fraction |
| POLR2F | POLR2E | 1.0 | 0.949 | hein_WMM bioplex (POLR2E) bioplex_WMM youn_WMM hein (POLR2F) fraction |
| POLR2B | POLR2I | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo fraction |
| POLR2B | POLR2L | 1.0 | 0.949 | bioplex_WMM youn_WMM Malo fraction |
| POLR2D | POLR2B | 0.999 | 0.949 | hein_WMM bioplex (POLR2D) bioplex_WMM youn_WMM Malo fraction |
| POLR2A | POLR2J | 0.999 | 0.948 | bioplex_WMM youn_WMM Malo fraction |
| POLR2F | POLR2A | 0.998 | 0.941 | hein_WMM bioplex_WMM youn_WMM hein (POLR2F) fraction |
| POLR2G | POLR2B | 0.997 | 0.932 | hein_WMM bioplex (POLR2G) bioplex_WMM youn_WMM hein (POLR2G) |
| POLR2D | POLR2I | 0.997 | 0.931 | hein_WMM bioplex_WMM youn_WMM Malo fraction |
| POLR2B | POLR2J | 0.996 | 0.926 | bioplex_WMM youn_WMM Malo fraction |
| POLR2C | POLR2I | 0.996 | 0.926 | hein_WMM bioplex_WMM youn_WMM Malo fraction |
| POLR2C | POLR2J | 0.996 | 0.924 | bioplex_WMM youn_WMM Malo fraction |
| RPRD1B | POLR2I | 0.995 | 0.924 | hein_WMM bioplex (RPRD1B) bioplex_WMM youn_WMM hein (RPRD1B) |
| POLR2D | RPRD1B | 0.992 | 0.912 | hein_WMM bioplex (POLR2D,RPRD1B) bioplex_WMM youn_WMM hein (RPRD1B) |
| POLR2E | POLR2L | 0.988 | 0.901 | bioplex (POLR2E) bioplex_WMM youn_WMM fraction |
| POLR2B | POLR2E | 0.988 | 0.901 | hein_WMM bioplex (POLR2E) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| POLR2F | POLR2H | 0.988 | 0.901 | hein_WMM bioplex_WMM youn_WMM hein (POLR2F) fraction |
| POLR2C | POLR2E | 0.988 | 0.901 | hein_WMM bioplex (POLR2E) bioplex_WMM youn_WMM gupta_WMM fraction |
| POLR2E | POLR2I | 0.988 | 0.901 | hein_WMM bioplex (POLR2E) bioplex_WMM youn_WMM fraction |
| POLR2G | POLR2E | 0.988 | 0.901 | hein_WMM bioplex (POLR2E,POLR2G) bioplex_WMM youn_WMM hein (POLR2G) fraction |
| POLR2F | POLR2I | 0.987 | 0.902 | hein_WMM bioplex_WMM youn_WMM hein (POLR2F) fraction |
| POLR2G | RPRD1B | 0.986 | 0.901 | hein_WMM bioplex (POLR2G,RPRD1B) bioplex_WMM youn_WMM hein (RPRD1B) |
| GPN1 | POLR2G | 0.977 | 0.893 | hein_WMM bioplex (POLR2G) bioplex_WMM hein (POLR2G) |
| POLR2C | RPRD1B | 0.974 | 0.886 | hein_WMM bioplex (RPRD1B) bioplex_WMM youn_WMM hein (RPRD1B) gupta_WMM |
| POLR2A | RPRD1B | 0.973 | 0.886 | hein_WMM bioplex (RPRD1B) bioplex_WMM youn_WMM hein (RPRD1B) gupta_WMM |
| POLR2G | POLR2H | 0.973 | 0.886 | hein_WMM bioplex (POLR2G) bioplex_WMM youn_WMM hein (POLR2G) |
| GPN3 | POLR2G | 0.967 | 0.879 | hein_WMM bioplex (GPN3,POLR2G) bioplex_WMM hein (POLR2G) |
| POLR2H | POLR2B | 0.945 | 0.856 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| POLR2A | POLR2H | 0.937 | 0.85 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| RPAP2 | RPRD1B | 0.936 | 0.85 | hein_WMM bioplex (RPRD1B) bioplex_WMM youn_WMM hein (RPRD1B) gupta_WMM |
| POLR2F | POLR2C | 0.927 | 0.844 | hein_WMM bioplex_WMM youn_WMM hein (POLR2F) fraction |
| POLR2F | POLR2G | 0.925 | 0.843 | hein_WMM bioplex (POLR2G) bioplex_WMM youn_WMM hein (POLR2F) |
| GPN3 | RPAP2 | 0.9 | 0.825 | hein_WMM bioplex (GPN3) bioplex_WMM youn_WMM |
| POLR2F | POLR2B | 0.892 | 0.819 | hein_WMM bioplex_WMM youn_WMM hein (POLR2F) fraction |
| POLR2C | POLR2H | 0.885 | 0.817 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| POLR2D | MYZAP | 0.885 | 0.816 | bioplex (MYZAP,POLR2D) bioplex_WMM |
| POLR2H | POLR2I | 0.823 | 0.774 | hein_WMM bioplex_WMM youn_WMM fraction |
| GPN1 | GPN3 | 0.812 | 0.772 | hein_WMM bioplex (GPN3) bioplex_WMM youn_WMM |
| RPRD1B | POLR2B | 0.72 | 0.731 | hein_WMM bioplex (RPRD1B) bioplex_WMM youn_WMM hein (RPRD1B) gupta_WMM |
| RPRD1B | POLR2J | 0.693 | 0.717 | bioplex (RPRD1B) bioplex_WMM youn_WMM |
| MYZAP | RPAP2 | 0.688 | 0.713 | bioplex (MYZAP) bioplex_WMM |
| POLR2F | GPN3 | 0.668 | 0.702 | hein_WMM bioplex (GPN3) bioplex_WMM hein (POLR2F) fraction |
| POLR2G | MYZAP | 0.659 | 0.696 | bioplex (MYZAP,POLR2G) bioplex_WMM |
| MYZAP | POLR2J | 0.572 | 0.655 | bioplex (MYZAP) bioplex_WMM |
| POLR2C | MYZAP | 0.547 | 0.642 | bioplex (MYZAP) bioplex_WMM |
| MYZAP | POLR2I | 0.491 | 0.619 | bioplex (MYZAP) bioplex_WMM |
| GPN1 | MYZAP | 0.414 | 0.571 | bioplex (MYZAP) bioplex_WMM gupta_WMM |
| POLR2D | RPAP2 | 0.324 | 0.513 | hein_WMM bioplex (POLR2D) bioplex_WMM youn_WMM |
| POLR2D | POLR2E | 0.314 | 0.508 | hein_WMM bioplex (POLR2D,POLR2E) bioplex_WMM youn_WMM fraction |
| POLR2A | MYZAP | 0.264 | 0.481 | bioplex (MYZAP) bioplex_WMM gupta_WMM |
| POLR2H | POLR2L | 0.232 | 0.47 | hein_WMM bioplex_WMM youn_WMM fraction |
| POLR2G | POLR2J | 0.197 | 0.45 | bioplex (POLR2G) bioplex_WMM youn_WMM |
| GPN3 | POLR2I | 0.183 | 0.437 | hein_WMM bioplex (GPN3) bioplex_WMM youn_WMM |
| RPAP2 | POLR2E | 0.164 | 0.42 | hein_WMM bioplex (POLR2E) bioplex_WMM youn_WMM gupta_WMM |
| GPN3 | MYZAP | 0.161 | 0.417 | bioplex (GPN3,MYZAP) bioplex_WMM |
| GPN3 | POLR2D | 0.15 | 0.41 | hein_WMM bioplex (GPN3,POLR2D) bioplex_WMM |
| RPRD1B | POLR2L | 0.127 | 0.398 | bioplex (RPRD1B) bioplex_WMM youn_WMM |
| GPN1 | POLR2E | 0.127 | 0.398 | hein_WMM bioplex (POLR2E) bioplex_WMM youn_WMM gupta_WMM |
| MYZAP | POLR2L | 0.1 | 0.36 | bioplex (MYZAP) bioplex_WMM |
| POLR2F | MYZAP | 0.098 | 0.358 | bioplex (MYZAP) bioplex_WMM |
| GPN3 | POLR2C | 0.098 | 0.358 | hein_WMM bioplex (GPN3) bioplex_WMM youn_WMM |
| MYZAP | RPRD1B | 0.095 | 0.357 | bioplex (MYZAP,RPRD1B) bioplex_WMM |
| POLR2D | POLR2J | 0.077 | 0.351 | bioplex (POLR2D) bioplex_WMM youn_WMM |
| POLR2A | RPAP2 | 0.073 | 0.357 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GPN3 | POLR2E | 0.072 | 0.353 | hein_WMM bioplex (GPN3,POLR2E) bioplex_WMM youn_WMM |
| GPN3 | RPRD1B | 0.066 | 0.347 | bioplex (RPRD1B) bioplex_WMM youn_WMM |
| RPRD1B | POLR2E | 0.065 | 0.347 | bioplex (RPRD1B) bioplex_WMM youn_WMM gupta_WMM fraction |
| GPN3 | POLR2A | 0.062 | 0.344 | hein_WMM bioplex (GPN3) bioplex_WMM youn_WMM |
| POLR2D | POLR2L | 0.043 | 0.27 | bioplex (POLR2D) bioplex_WMM youn_WMM |
| MYZAP | POLR2E | 0.041 | 0.271 | bioplex (MYZAP,POLR2E) bioplex_WMM gupta_WMM |
| RPAP2 | POLR2I | 0.038 | 0.265 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| POLR2D | POLR2H | 0.032 | 0.245 | hein_WMM bioplex (POLR2D) bioplex_WMM youn_WMM |
| GPN1 | POLR2D | 0.028 | 0.231 | hein_WMM bioplex (POLR2D) bioplex_WMM |
| POLR2E | POLR2J | 0.028 | 0.231 | bioplex (POLR2E) bioplex_WMM youn_WMM |
| POLR2C | RPAP2 | 0.026 | 0.215 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| POLR2F | POLR2D | 0.025 | 0.211 | bioplex (POLR2D) bioplex_WMM youn_WMM |
| GPN1 | RPAP2 | 0.025 | 0.211 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| GPN3 | POLR2H | 0.022 | 0.198 | hein_WMM bioplex (GPN3) bioplex_WMM youn_WMM fraction |
| RPAP2 | POLR2B | 0.02 | 0.187 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MYZAP | POLR2H | 0.02 | 0.187 | bioplex (MYZAP) bioplex_WMM |
| GPN1 | POLR2L | 0.02 | 0.189 | bioplex_WMM WMM_only |
| GPN1 | POLR2F | 0.019 | 0.181 | hein_WMM bioplex_WMM hein (POLR2F) |
| GPN1 | POLR2J | 0.019 | 0.185 | bioplex_WMM WMM_only |
| RPAP2 | POLR2J | 0.017 | 0.173 | bioplex_WMM youn_WMM WMM_only |
| POLR2H | RPAP2 | 0.017 | 0.173 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| POLR2J | POLR2L | 0.017 | 0.171 | bioplex_WMM youn_WMM WMM_only |
| POLR2F | RPAP2 | 0.016 | 0.164 | hein_WMM bioplex_WMM youn_WMM hein (POLR2F) |
| GPN1 | POLR2H | 0.016 | 0.155 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| GPN1 | POLR2I | 0.015 | 0.146 | hein_WMM bioplex_WMM WMM_only |
| POLR2H | POLR2J | 0.015 | 0.146 | bioplex_WMM youn_WMM WMM_only |
| POLR2I | POLR2J | 0.014 | 0.137 | bioplex_WMM youn_WMM WMM_only |
| GPN1 | POLR2C | 0.013 | 0.143 | hein_WMM bioplex_WMM WMM_only boldt_WMM |
| RPAP2 | POLR2L | 0.012 | 0.147 | bioplex_WMM youn_WMM WMM_only |
| POLR2F | POLR2J | 0.012 | 0.147 | bioplex_WMM youn_WMM WMM_only |
| GPN1 | POLR2B | 0.011 | 0.142 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| GPN3 | POLR2B | 0.011 | 0.143 | hein_WMM bioplex (GPN3) bioplex_WMM youn_WMM |
| GPN3 | POLR2J | 0.01 | 0.109 | bioplex_WMM WMM_only |
| POLR2F | POLR2L | 0.01 | 0.103 | bioplex_WMM youn_WMM WMM_only |
| MYZAP | POLR2B | 0.005 | 0.006 | bioplex (MYZAP) bioplex_WMM gupta_WMM fraction |
| GPN3 | POLR2L | 0.005 | 0.008 | bioplex (GPN3) bioplex_WMM |
| GPN1 | RPRD1B | 0.003 | 0.02 | bioplex (RPRD1B) bioplex_WMM youn_WMM |
| POLR2F | RPRD1B | 0.0 | 0.008 | bioplex (RPRD1B) bioplex_WMM youn_WMM |
| POLR2H | RPRD1B | 0.0 | 0.008 | bioplex (RPRD1B) bioplex_WMM youn_WMM gupta_WMM fraction |
| GPN1 | POLR2A | 0.0 | 0.012 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_05766 has an average edge precision of 0.575 which is ranked 2052 out of all 6965 complexes.
Related Complexes