hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05775
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PIANP | PILR alpha-associated neural protein (PILR-associating neural protein) (Paired immunoglobin-like type 2 receptor-associating neural protein) | UniProt NCBI |
| LAMP3 | Lysosome-associated membrane glycoprotein 3 (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD antigen CD208) | UniProt NCBI |
| MARCH5 | E3 ubiquitin-protein ligase MARCH5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (Mitochondrial ubiquitin ligase) (MITOL) (RING finger protein 153) (RING-type E3 ubiquitin transferase MARCH5) | UniProt NCBI |
| GALNT12 | Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) | UniProt NCBI |
| GALNT4 | Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00512 | 0.00128409257805 | 0.4 | GALNT4 GALNT12 | Mucin type O-glycan biosynthesis |
| REAC:R-HSA-913709 | 0.0151315666639 | 0.4 | GALNT4 GALNT12 | O-linked glycosylation of mucins |
| REAC:R-HSA-5173105 | 0.0476518941102 | 0.4 | GALNT4 GALNT12 | O-linked glycosylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GALNT4 | PIANP | 0.18 | 0.437 | bioplex (PIANP) bioplex_WMM |
| LAMP3 | GALNT4 | 0.05 | 0.298 | bioplex (LAMP3) bioplex_WMM |
| LAMP3 | MARCH5 | 0.046 | 0.292 | bioplex (LAMP3) bioplex_WMM |
| PIANP | GALNT12 | 0.023 | 0.209 | bioplex (PIANP) bioplex_WMM |
| GALNT4 | GALNT12 | 0.008 | 0.088 | bioplex_WMM WMM_only |
| MARCH5 | GALNT4 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| MARCH5 | GALNT12 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| LAMP3 | GALNT12 | 0.005 | 0.013 | bioplex (LAMP3) bioplex_WMM |
Images
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Complex HuMAP2_05775 has an average edge precision of 0.169 which is ranked 6538 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PIANP | HuMAP2_04749 HuMAP2_05775 HuMAP2_06027 |
| LAMP3 | HuMAP2_00249 HuMAP2_02829 HuMAP2_03845 HuMAP2_05775 |
| MARCH5 | HuMAP2_00249 HuMAP2_02829 HuMAP2_03845 HuMAP2_05127 HuMAP2_05775 |
| GALNT12 | HuMAP2_04749 HuMAP2_05775 |
| GALNT4 | HuMAP2_03845 HuMAP2_04749 HuMAP2_05775 HuMAP2_06027 |