hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05790
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EXOSC10 | Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2) | UniProt NCBI |
| EXOSC3 | Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10) | UniProt NCBI |
| DIS3L | DIS3-like exonuclease 1 (EC 3.1.13.-) | UniProt NCBI |
| EXOSC1 | Exosome complex component CSL4 (Exosome component 1) | UniProt NCBI |
| EXOSC4 | Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A) | UniProt NCBI |
| EXOSC8 | Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9) | UniProt NCBI |
| EXOSC5 | Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B) | UniProt NCBI |
| EXOSC7 | Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8) | UniProt NCBI |
| EXOSC9 | Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) | UniProt NCBI |
| EXOSC6 | Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11) | UniProt NCBI |
| EXOSC2 | Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) | UniProt NCBI |
| MPHOSPH6 | M-phase phosphoprotein 6 | UniProt NCBI |
| RBM7 | RNA-binding protein 7 (RNA-binding motif protein 7) | UniProt NCBI |
| C1D | Nuclear nucleic acid-binding protein C1D (hC1D) | UniProt NCBI |
| ZCCHC8 | Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7443 | 9.0946457686e-38 | 0.8 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC7 EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | Exosome |
| GO:0000178 | 4.61572931715e-32 | 0.866666666667 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | exosome (RNase complex) |
| GO:1905354 | 4.61572931715e-32 | 0.866666666667 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | exoribonuclease complex |
| GO:0000176 | 1.67053368577e-31 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | nuclear exosome (RNase complex) |
| CORUM:789 | 1.1077097299e-29 | 0.666666666667 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Exosome |
| KEGG:03018 | 2.9976295152e-27 | 0.866666666667 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | RNA degradation |
| CORUM:788 | 2.49807769552e-26 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Exosome |
| GO:0016075 | 1.97439270857e-23 | 0.666666666667 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | rRNA catabolic process |
| REAC:R-HSA-429958 | 1.54844117281e-22 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | mRNA decay by 3' to 5' exoribonuclease |
| REAC:R-HSA-450513 | 3.28924330307e-22 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA |
| REAC:R-HSA-450385 | 3.28924330307e-22 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA |
| REAC:R-HSA-450604 | 3.28924330307e-22 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | KSRP (KHSRP) binds and destabilizes mRNA |
| GO:0071028 | 1.80202393655e-21 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | nuclear mRNA surveillance |
| GO:0071027 | 1.80202393655e-21 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | nuclear RNA surveillance |
| GO:0071025 | 5.04383612816e-21 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | RNA surveillance |
| GO:0000177 | 5.04383612816e-21 | 0.6 | EXOSC9 DIS3L EXOSC4 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | cytoplasmic exosome (RNase complex) |
| GO:0034475 | 5.36741125673e-21 | 0.533333333333 | EXOSC9 EXOSC5 EXOSC8 EXOSC6 EXOSC4 EXOSC2 EXOSC7 EXOSC3 | U4 snRNA 3'-end processing |
| REAC:R-HSA-380994 | 1.76461632115e-20 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | ATF4 activates genes in response to endoplasmic reticulum stress |
| GO:0034661 | 2.0260342329e-20 | 0.666666666667 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | ncRNA catabolic process |
| GO:0034427 | 4.82865095176e-20 | 0.533333333333 | EXOSC9 EXOSC5 EXOSC8 EXOSC6 EXOSC4 EXOSC2 EXOSC7 EXOSC3 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' |
| REAC:R-HSA-381042 | 1.34917956208e-19 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | PERK regulates gene expression |
| GO:0016072 | 4.51301394051e-19 | 0.866666666667 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | rRNA metabolic process |
| REAC:R-HSA-6791226 | 8.50833689775e-19 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 1.65171510489e-18 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 3.09629209726e-18 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | rRNA processing |
| GO:0000460 | 3.28218635733e-18 | 0.6 | EXOSC9 EXOSC4 EXOSC10 EXOSC3 EXOSC7 EXOSC8 EXOSC2 MPHOSPH6 C1D | maturation of 5.8S rRNA |
| GO:0006364 | 9.05241352285e-17 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | rRNA processing |
| GO:0043928 | 9.64977977992e-17 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | exonucleolytic catabolism of deadenylated mRNA |
| REAC:R-HSA-429914 | 1.01063406617e-16 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Deadenylation-dependent mRNA decay |
| GO:0016073 | 1.31189328993e-16 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | snRNA metabolic process |
| GO:0000291 | 1.76536860176e-16 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | nuclear-transcribed mRNA catabolic process, exonucleolytic |
| GO:0043628 | 3.1081515202e-16 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | ncRNA 3'-end processing |
| GO:0034472 | 1.70631695106e-15 | 0.533333333333 | EXOSC9 EXOSC5 EXOSC8 EXOSC6 EXOSC4 EXOSC2 EXOSC7 EXOSC3 | snRNA 3'-end processing |
| GO:0042254 | 3.92126376038e-15 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | ribosome biogenesis |
| REAC:R-HSA-381119 | 4.34187721809e-15 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Unfolded Protein Response (UPR) |
| REAC:R-HSA-450531 | 4.86113079012e-15 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Regulation of mRNA stability by proteins that bind AU-rich elements |
| GO:0034660 | 1.61253128273e-14 | 0.866666666667 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | ncRNA metabolic process |
| GO:0071029 | 1.65225062463e-14 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | nuclear ncRNA surveillance |
| GO:0071035 | 1.65225062463e-14 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | nuclear polyadenylation-dependent rRNA catabolic process |
| GO:0071038 | 1.65225062463e-14 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | nuclear polyadenylation-dependent tRNA catabolic process |
| GO:0071046 | 1.65225062463e-14 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | nuclear polyadenylation-dependent ncRNA catabolic process |
| GO:0016180 | 1.65434948367e-14 | 0.533333333333 | EXOSC9 EXOSC5 EXOSC8 EXOSC6 EXOSC4 EXOSC2 EXOSC7 EXOSC3 | snRNA processing |
| GO:0043634 | 1.15597615235e-13 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | polyadenylation-dependent ncRNA catabolic process |
| GO:0071051 | 1.15597615235e-13 | 0.4 | EXOSC4 EXOSC5 EXOSC10 EXOSC6 EXOSC2 EXOSC3 | polyadenylation-dependent snoRNA 3'-end processing |
| GO:0000175 | 1.24907440686e-13 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | 3'-5'-exoribonuclease activity |
| GO:0034470 | 1.39847824144e-13 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | ncRNA processing |
| GO:0000288 | 1.60543634196e-13 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| GO:0016896 | 2.04725911946e-13 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | exoribonuclease activity, producing 5'-phosphomonoesters |
| GO:0004532 | 3.25967527302e-13 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | exoribonuclease activity |
| GO:0043633 | 4.62150859702e-13 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | polyadenylation-dependent RNA catabolic process |
| GO:0000459 | 4.62150859702e-13 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | exonucleolytic trimming involved in rRNA processing |
| GO:0016078 | 4.62150859702e-13 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | tRNA catabolic process |
| GO:0000467 | 4.62150859702e-13 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0006396 | 6.44985014272e-13 | 0.933333333333 | EXOSC9 RBM7 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | RNA processing |
| GO:0022613 | 9.85489148041e-13 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | ribonucleoprotein complex biogenesis |
| GO:0031125 | 1.3857341134e-12 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | rRNA 3'-end processing |
| GO:0016796 | 4.66848732384e-12 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| REAC:R-HSA-8953854 | 4.86676337322e-12 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | Metabolism of RNA |
| GO:0008408 | 6.40785816267e-12 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | 3'-5' exonuclease activity |
| GO:0031126 | 7.61364007486e-12 | 0.4 | EXOSC4 EXOSC5 EXOSC10 EXOSC6 EXOSC2 EXOSC3 | snoRNA 3'-end processing |
| GO:0000956 | 1.84758862439e-11 | 0.666666666667 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | nuclear-transcribed mRNA catabolic process |
| GO:0090503 | 2.82499283962e-11 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | RNA phosphodiester bond hydrolysis, exonucleolytic |
| GO:0043144 | 2.82499283962e-11 | 0.4 | EXOSC4 EXOSC5 EXOSC10 EXOSC6 EXOSC2 EXOSC3 | snoRNA processing |
| GO:0016074 | 4.94117498871e-11 | 0.4 | EXOSC4 EXOSC5 EXOSC10 EXOSC6 EXOSC2 EXOSC3 | snoRNA metabolic process |
| GO:0031123 | 7.03513739148e-11 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | RNA 3'-end processing |
| GO:0004527 | 9.83653507022e-11 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | exonuclease activity |
| GO:0006401 | 1.09568396277e-10 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | RNA catabolic process |
| GO:0000469 | 1.31628097145e-10 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | cleavage involved in rRNA processing |
| GO:1902494 | 2.96541252908e-10 | 0.933333333333 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | catalytic complex |
| GO:0043488 | 3.39645360264e-10 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | regulation of mRNA stability |
| GO:0043487 | 4.26585038484e-10 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | regulation of RNA stability |
| GO:0000466 | 4.45277469021e-10 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:1903311 | 8.04211557193e-10 | 0.666666666667 | EXOSC9 RBM7 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | regulation of mRNA metabolic process |
| GO:0061013 | 9.55155366321e-10 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | regulation of mRNA catabolic process |
| GO:0004540 | 1.04325969801e-09 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | ribonuclease activity |
| GO:0034655 | 1.2926556861e-09 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | nucleobase-containing compound catabolic process |
| GO:0016071 | 2.6394858596e-09 | 0.8 | EXOSC9 RBM7 EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 ZCCHC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | mRNA metabolic process |
| GO:0046700 | 2.90020467538e-09 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | heterocycle catabolic process |
| GO:0044270 | 2.96536576329e-09 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | cellular nitrogen compound catabolic process |
| GO:0019439 | 3.85783674532e-09 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | aromatic compound catabolic process |
| GO:0006402 | 4.18484490971e-09 | 0.666666666667 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | mRNA catabolic process |
| GO:1901361 | 5.89899738279e-09 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | organic cyclic compound catabolic process |
| CORUM:0000000 | 1.26324798585e-08 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | CORUM root |
| GO:0004518 | 6.05219390408e-08 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | nuclease activity |
| GO:0090501 | 1.98385951596e-07 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | RNA phosphodiester bond hydrolysis |
| GO:0016070 | 3.05972102898e-06 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | RNA metabolic process |
| GO:0044265 | 4.43578728229e-06 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | cellular macromolecule catabolic process |
| CORUM:822 | 4.88886381083e-06 | 0.2 | EXOSC4 EXOSC10 EXOSC2 | mRNA decay complex (UPF1, UPF2, UPF3B, DCP2, XRN1, XRN2, EXOSC2, EXOSC4, EXOSC10, PARN) |
| GO:0140098 | 8.66800858064e-06 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | catalytic activity, acting on RNA |
| GO:0010608 | 8.9744074163e-06 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | posttranscriptional regulation of gene expression |
| GO:0003723 | 1.0075084349e-05 | 0.8 | EXOSC9 RBM7 EXOSC4 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 ZCCHC8 | RNA binding |
| GO:0045006 | 1.09435954146e-05 | 0.266666666667 | EXOSC6 EXOSC3 EXOSC5 EXOSC4 | DNA deamination |
| GO:0005730 | 1.16442972286e-05 | 0.666666666667 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC2 MPHOSPH6 EXOSC3 | nucleolus |
| GO:0090304 | 1.72250129892e-05 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | nucleic acid metabolic process |
| GO:0009057 | 2.48884747341e-05 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | macromolecule catabolic process |
| GO:0034476 | 4.13224520905e-05 | 0.2 | EXOSC9 EXOSC7 EXOSC8 | U5 snRNA 3'-end processing |
| GO:0034473 | 4.13224520905e-05 | 0.2 | EXOSC9 EXOSC7 EXOSC8 | U1 snRNA 3'-end processing |
| GO:0090305 | 8.41053462399e-05 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | nucleic acid phosphodiester bond hydrolysis |
| GO:0006139 | 8.96917039568e-05 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | nucleobase-containing compound metabolic process |
| CORUM:7349 | 0.000140521514535 | 0.133333333333 | RBM7 ZCCHC8 | MTR4-RBM7-ZCCHC8 complex |
| GO:0031329 | 0.000146033857355 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | regulation of cellular catabolic process |
| GO:0046483 | 0.000150781122 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | heterocycle metabolic process |
| GO:0006725 | 0.000158842430471 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | cellular aromatic compound metabolic process |
| GO:0071043 | 0.000165189908538 | 0.2 | EXOSC2 EXOSC10 EXOSC3 | CUT metabolic process |
| GO:0071047 | 0.000165189908538 | 0.2 | EXOSC9 EXOSC7 EXOSC8 | polyadenylation-dependent mRNA catabolic process |
| GO:0071034 | 0.000165189908538 | 0.2 | EXOSC2 EXOSC10 EXOSC3 | CUT catabolic process |
| GO:0071042 | 0.000165189908538 | 0.2 | EXOSC9 EXOSC7 EXOSC8 | nuclear polyadenylation-dependent mRNA catabolic process |
| GO:0006399 | 0.00022812806265 | 0.4 | EXOSC9 EXOSC8 EXOSC10 EXOSC7 EXOSC2 EXOSC3 | tRNA metabolic process |
| GO:0035327 | 0.000241010060666 | 0.266666666667 | EXOSC4 EXOSC10 EXOSC5 EXOSC3 | transcriptionally active chromatin |
| GO:0005654 | 0.000248876919368 | 0.933333333333 | EXOSC9 RBM7 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | nucleoplasm |
| GO:1901360 | 0.000282451275064 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | organic cyclic compound metabolic process |
| GO:0071033 | 0.000412725169389 | 0.2 | EXOSC2 EXOSC10 EXOSC3 | nuclear retention of pre-mRNA at the site of transcription |
| GO:0009894 | 0.00054516740579 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | regulation of catabolic process |
| GO:0034641 | 0.000650430346462 | 1.0 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC5 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 RBM7 | cellular nitrogen compound metabolic process |
| GO:0016788 | 0.00103824081075 | 0.533333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC7 EXOSC2 EXOSC3 EXOSC5 | hydrolase activity, acting on ester bonds |
| GO:1901575 | 0.00163676680876 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | organic substance catabolic process |
| GO:0010467 | 0.00177146809233 | 0.933333333333 | EXOSC9 RBM7 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | gene expression |
| GO:0031981 | 0.00332808920359 | 0.933333333333 | EXOSC9 RBM7 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | nuclear lumen |
| WP:WP4352 | 0.00333045326698 | 0.266666666667 | EXOSC9 EXOSC7 EXOSC2 EXOSC4 | Ciliary landscape |
| GO:0044248 | 0.00373905957206 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | cellular catabolic process |
| REAC:R-HSA-392499 | 0.00381775107112 | 0.6 | EXOSC9 EXOSC5 EXOSC4 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | Metabolism of proteins |
| GO:0010629 | 0.00554598879079 | 0.666666666667 | EXOSC9 EXOSC5 EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 | negative regulation of gene expression |
| GO:0044085 | 0.0062577404106 | 0.8 | EXOSC9 EXOSC5 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 | cellular component biogenesis |
| GO:0008298 | 0.00678530576901 | 0.2 | EXOSC2 EXOSC10 EXOSC3 | intracellular mRNA localization |
| GO:0003676 | 0.00758553498499 | 0.8 | EXOSC9 RBM7 EXOSC4 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 ZCCHC8 | nucleic acid binding |
| GO:0044428 | 0.00800798236064 | 0.933333333333 | EXOSC9 RBM7 EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | nuclear part |
| GO:0009056 | 0.0126445494482 | 0.733333333333 | EXOSC9 DIS3L EXOSC4 EXOSC10 EXOSC1 EXOSC6 EXOSC8 EXOSC2 EXOSC7 EXOSC3 EXOSC5 | catabolic process |
| GO:0032991 | 0.0139875206848 | 0.933333333333 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 ZCCHC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | protein-containing complex |
| KEGG:00000 | 0.0252253336476 | 0.866666666667 | EXOSC9 DIS3L EXOSC4 EXOSC7 EXOSC10 EXOSC1 C1D EXOSC6 EXOSC8 EXOSC2 MPHOSPH6 EXOSC3 EXOSC5 | KEGG root term |
| GO:0071031 | 0.0473364581948 | 0.133333333333 | EXOSC2 EXOSC3 | nuclear mRNA surveillance of mRNA 3'-end processing |
| GO:0071049 | 0.0473364581948 | 0.133333333333 | EXOSC2 EXOSC3 | nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription |
| CORUM:2004 | 0.0498572752401 | 0.0666666666667 | C1D | C1D homodimer protein |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EXOSC2 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC2) Malo gupta_WMM fraction treiber_WMM |
| EXOSC2 | EXOSC10 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC2) Malo gupta_WMM fraction |
| EXOSC1 | EXOSC10 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| RBM7 | ZCCHC8 | 1.0 | 0.949 | hein_WMM bioplex (RBM7) bioplex_WMM Guru youn_WMM hein (RBM7) fraction |
| EXOSC3 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC9 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru boldt youn_WMM hein (EXOSC9) Malo gupta_WMM fraction boldt_WMM |
| EXOSC2 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru boldt youn_WMM hein (EXOSC2) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EXOSC9 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC9) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (EXOSC2,EXOSC4) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| MPHOSPH6 | EXOSC1 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC10 | EXOSC8 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC8) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| EXOSC4 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC4) Malo gupta_WMM fraction treiber_WMM |
| EXOSC10 | EXOSC7 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC7) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC2 | EXOSC1 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC2) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru boldt youn_WMM hein (EXOSC4) Malo gupta_WMM fraction boldt_WMM |
| EXOSC1 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1,EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC10 | EXOSC9 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC9) Malo gupta_WMM fraction treiber_WMM |
| EXOSC4 | EXOSC1 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC4) Malo gupta_WMM fraction |
| EXOSC3 | DIS3L | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM youn_WMM hein (DIS3L) gupta_WMM |
| EXOSC1 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1,EXOSC8) bioplex_WMM youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC2 | EXOSC9 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (EXOSC2,EXOSC9) Malo gupta_WMM fraction boldt_WMM |
| EXOSC1 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1,EXOSC7) bioplex_WMM Guru youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC1 | EXOSC9 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC9) Malo gupta_WMM fraction |
| EXOSC3 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3,EXOSC7) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC9 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC5,EXOSC9) Malo gupta_WMM fraction |
| EXOSC10 | EXOSC5 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC9 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (EXOSC4,EXOSC9) Malo gupta_WMM fraction boldt_WMM |
| EXOSC4 | EXOSC10 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC4) Malo gupta_WMM fraction |
| EXOSC2 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC2,EXOSC5) Malo gupta_WMM fraction |
| EXOSC9 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC9) gupta_WMM |
| EXOSC8 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC2 | MPHOSPH6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC2) Malo gupta_WMM fraction |
| EXOSC2 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC2) Malo gupta_WMM fraction treiber_WMM |
| EXOSC4 | MPHOSPH6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC4) Malo gupta_WMM fraction |
| EXOSC1 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC5) Malo gupta_WMM fraction |
| EXOSC10 | EXOSC3 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC3) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC4 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC4) gupta_WMM treiber_WMM |
| MPHOSPH6 | EXOSC5 | 0.999 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC6 | EXOSC3 | 0.999 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| EXOSC5 | EXOSC7 | 0.999 | 0.948 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| DIS3L | EXOSC8 | 0.999 | 0.948 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (DIS3L) |
| MPHOSPH6 | EXOSC7 | 0.999 | 0.946 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC4 | EXOSC6 | 0.997 | 0.931 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC4) Malo gupta_WMM fraction |
| DIS3L | EXOSC7 | 0.996 | 0.927 | hein_WMM bioplex (EXOSC7) bioplex_WMM youn_WMM gupta_WMM |
| MPHOSPH6 | EXOSC9 | 0.995 | 0.924 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC9) Malo gupta_WMM fraction |
| MPHOSPH6 | EXOSC10 | 0.993 | 0.918 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| MPHOSPH6 | EXOSC3 | 0.992 | 0.912 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC1 | DIS3L | 0.99 | 0.907 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) |
| EXOSC2 | EXOSC6 | 0.989 | 0.903 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC2) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC5 | 0.988 | 0.902 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC4,EXOSC5) Malo gupta_WMM fraction |
| EXOSC8 | EXOSC7 | 0.978 | 0.894 | hein_WMM bioplex (EXOSC7,EXOSC8) bioplex_WMM youn_WMM gupta_WMM |
| RBM7 | EXOSC3 | 0.975 | 0.887 | hein_WMM bioplex (EXOSC3) bioplex_WMM youn_WMM hein (RBM7) |
| C1D | EXOSC5 | 0.972 | 0.886 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM hein (EXOSC5) fraction |
| EXOSC3 | EXOSC8 | 0.969 | 0.881 | hein_WMM bioplex (EXOSC3,EXOSC8) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| EXOSC10 | C1D | 0.96 | 0.865 | hein_WMM youn (EXOSC10) bioplex (C1D) bioplex_WMM |
| EXOSC3 | C1D | 0.945 | 0.856 | hein_WMM bioplex (C1D,EXOSC3) bioplex_WMM youn_WMM |
| C1D | EXOSC7 | 0.939 | 0.851 | hein_WMM bioplex (C1D,EXOSC7) bioplex_WMM youn_WMM |
| RBM7 | EXOSC10 | 0.938 | 0.85 | hein_WMM youn (EXOSC10) bioplex (RBM7) bioplex_WMM youn_WMM hein (RBM7) |
| RBM7 | EXOSC7 | 0.919 | 0.842 | bioplex (EXOSC7,RBM7) bioplex_WMM youn_WMM |
| EXOSC1 | EXOSC6 | 0.894 | 0.82 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) gupta_WMM |
| EXOSC6 | EXOSC7 | 0.875 | 0.807 | hein_WMM bioplex (EXOSC7) bioplex_WMM youn_WMM gupta_WMM |
| EXOSC9 | C1D | 0.866 | 0.801 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM hein (EXOSC9) |
| EXOSC1 | C1D | 0.865 | 0.801 | hein_WMM bioplex (C1D,EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) |
| MPHOSPH6 | EXOSC6 | 0.844 | 0.788 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| EXOSC4 | C1D | 0.726 | 0.736 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM |
| MPHOSPH6 | EXOSC8 | 0.686 | 0.712 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| C1D | EXOSC8 | 0.599 | 0.67 | hein_WMM bioplex (C1D,EXOSC8) bioplex_WMM youn_WMM fraction |
| RBM7 | EXOSC8 | 0.531 | 0.636 | bioplex (EXOSC8) bioplex_WMM youn_WMM |
| EXOSC6 | EXOSC5 | 0.525 | 0.635 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC2 | C1D | 0.265 | 0.482 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM fraction |
| EXOSC6 | C1D | 0.237 | 0.47 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM |
| EXOSC2 | DIS3L | 0.078 | 0.352 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC2) gupta_WMM |
| RBM7 | C1D | 0.072 | 0.354 | bioplex (C1D) bioplex_WMM youn_WMM |
| MPHOSPH6 | C1D | 0.052 | 0.302 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM fraction |
| ZCCHC8 | EXOSC7 | 0.048 | 0.295 | bioplex (EXOSC7) bioplex_WMM youn_WMM gupta_WMM |
| EXOSC4 | DIS3L | 0.044 | 0.279 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC4) |
| ZCCHC8 | C1D | 0.042 | 0.269 | bioplex (C1D) bioplex_WMM youn_WMM |
| RBM7 | EXOSC1 | 0.041 | 0.27 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (RBM7) |
| DIS3L | EXOSC5 | 0.038 | 0.264 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC5) |
| EXOSC10 | EXOSC6 | 0.03 | 0.233 | hein_WMM youn (EXOSC10) bioplex_WMM youn_WMM gupta_WMM |
| EXOSC9 | EXOSC6 | 0.028 | 0.231 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC9) Malo gupta_WMM fraction |
| EXOSC9 | DIS3L | 0.027 | 0.225 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC9) |
| EXOSC6 | EXOSC8 | 0.025 | 0.21 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MPHOSPH6 | DIS3L | 0.022 | 0.204 | hein_WMM bioplex_WMM WMM_only |
| DIS3L | C1D | 0.021 | 0.195 | hein_WMM bioplex_WMM WMM_only |
| EXOSC6 | DIS3L | 0.017 | 0.171 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L) gupta_WMM |
| ZCCHC8 | EXOSC1 | 0.017 | 0.167 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM gupta_WMM |
| ZCCHC8 | EXOSC10 | 0.016 | 0.162 | hein_WMM youn (EXOSC10) bioplex_WMM youn_WMM gupta_WMM |
| ZCCHC8 | EXOSC5 | 0.014 | 0.137 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RBM7 | MPHOSPH6 | 0.014 | 0.142 | bioplex_WMM youn_WMM WMM_only |
| ZCCHC8 | MPHOSPH6 | 0.013 | 0.143 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EXOSC4 | RBM7 | 0.012 | 0.149 | bioplex_WMM youn_WMM WMM_only |
| EXOSC2 | ZCCHC8 | 0.012 | 0.15 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EXOSC10 | DIS3L | 0.011 | 0.144 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L) gupta_WMM |
| EXOSC2 | RBM7 | 0.011 | 0.14 | bioplex (RBM7) bioplex_WMM youn_WMM |
| ZCCHC8 | DIS3L | 0.011 | 0.142 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZCCHC8 | EXOSC9 | 0.01 | 0.139 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RBM7 | DIS3L | 0.01 | 0.126 | bioplex_WMM youn_WMM WMM_only |
| ZCCHC8 | EXOSC6 | 0.009 | 0.098 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZCCHC8 | EXOSC3 | 0.007 | 0.003 | hein_WMM bioplex (EXOSC3) bioplex_WMM youn_WMM gupta_WMM |
| ZCCHC8 | EXOSC8 | 0.007 | 0.001 | bioplex (EXOSC8) bioplex_WMM youn_WMM gupta_WMM |
| RBM7 | EXOSC5 | 0.004 | 0.01 | hein_WMM bioplex_WMM youn_WMM hein (RBM7) |
| EXOSC4 | ZCCHC8 | 0.003 | 0.007 | bioplex_WMM youn_WMM gupta_WMM fraction |
| RBM7 | EXOSC9 | 0.003 | 0.015 | hein_WMM bioplex (RBM7) bioplex_WMM youn_WMM hein (RBM7) |
| RBM7 | EXOSC6 | 0.0 | 0.012 | hein_WMM bioplex (RBM7) bioplex_WMM youn_WMM hein (RBM7) |
Images
Click to enlarge
Complex HuMAP2_05790 has an average edge precision of 0.658 which is ranked 1605 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EXOSC10 | HuMAP2_02326 HuMAP2_03073 HuMAP2_05790 |
| EXOSC3 | HuMAP2_03073 HuMAP2_05790 HuMAP2_06861 |
| DIS3L | HuMAP2_03073 HuMAP2_05790 |
| EXOSC1 | HuMAP2_02326 HuMAP2_03073 HuMAP2_05790 |
| EXOSC4 | HuMAP2_00994 HuMAP2_03073 HuMAP2_05790 |
| EXOSC8 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC5 | HuMAP2_03073 HuMAP2_05790 HuMAP2_06861 |
| EXOSC7 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC9 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC6 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC2 | HuMAP2_00994 HuMAP2_03073 HuMAP2_05790 |
| MPHOSPH6 | HuMAP2_01835 HuMAP2_02326 HuMAP2_03073 HuMAP2_05790 |
| RBM7 | HuMAP2_01425 HuMAP2_01715 HuMAP2_03073 HuMAP2_05790 |
| C1D | HuMAP2_03073 HuMAP2_05790 |
| ZCCHC8 | HuMAP2_01425 HuMAP2_01715 HuMAP2_05790 HuMAP2_06075 |