hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05792
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MIB2 | E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (Novel zinc finger protein) (Novelzin) (Putative NF-kappa-B-activating protein 002N) (RING-type E3 ubiquitin transferase MIB2) (Skeletrophin) (Zinc finger ZZ type with ankyrin repeat domain protein 1) | UniProt NCBI |
| ZNF518B | Zinc finger protein 518B | UniProt NCBI |
| TCF7L2 | Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4) | UniProt NCBI |
| IKZF5 | Zinc finger protein Pegasus (Ikaros family zinc finger protein 5) | UniProt NCBI |
| AHDC1 | AT-hook DNA-binding motif-containing protein 1 | UniProt NCBI |
| PEX14 | Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1984 | 0.0249904952816 | 0.166666666667 | PEX14 | PEX14 homodimer complex |
| CORUM:3155 | 0.0499726005494 | 0.166666666667 | TCF7L2 | TFC4-CTNNB1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TCF7L2 | IKZF5 | 0.986 | 0.901 | bioplex (IKZF5) bioplex_WMM |
| IKZF5 | AHDC1 | 0.191 | 0.444 | bioplex (IKZF5) bioplex_WMM |
| IKZF5 | MIB2 | 0.16 | 0.417 | bioplex (IKZF5) bioplex_WMM |
| IKZF5 | ZNF518B | 0.151 | 0.411 | bioplex (IKZF5) bioplex_WMM |
| IKZF5 | PEX14 | 0.065 | 0.347 | bioplex (IKZF5) bioplex_WMM |
| TCF7L2 | ZNF518B | 0.008 | 0.091 | bioplex_WMM WMM_only |
| AHDC1 | ZNF518B | 0.008 | 0.085 | bioplex_WMM WMM_only |
| MIB2 | ZNF518B | 0.008 | 0.082 | bioplex_WMM WMM_only |
| TCF7L2 | AHDC1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| TCF7L2 | MIB2 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| AHDC1 | MIB2 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| PEX14 | ZNF518B | 0.007 | 0.009 | bioplex_WMM youn_WMM WMM_only |
| TCF7L2 | PEX14 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| PEX14 | AHDC1 | 0.007 | 0.002 | bioplex_WMM gupta_WMM WMM_only |
| PEX14 | MIB2 | 0.007 | 0.005 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_05792 has an average edge precision of 0.196 which is ranked 6234 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MIB2 | HuMAP2_04950 HuMAP2_05792 |
| ZNF518B | HuMAP2_05792 |
| TCF7L2 | HuMAP2_01456 HuMAP2_05792 |
| IKZF5 | HuMAP2_01456 HuMAP2_04537 HuMAP2_05792 |
| AHDC1 | HuMAP2_03552 HuMAP2_03973 HuMAP2_05792 HuMAP2_06177 |
| PEX14 | HuMAP2_03546 HuMAP2_05792 |