hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05793
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| XRCC5 | X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)) | UniProt NCBI |
| XRCC6 | X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:328 | 1.67592346237e-06 | 1.0 | XRCC6 XRCC5 | Ku antigen complex |
| CORUM:4081 | 1.67592346237e-06 | 1.0 | XRCC6 XRCC5 | Ku antigen complex |
| CORUM:6310 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | DEAF1- complex |
| CORUM:5182 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | DNA-PK-Ku complex |
| CORUM:4082 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | XRCC6-XRCC5-WRN complex |
| CORUM:2918 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | Ku antigen-YY1-alphaMyHC promoter complex |
| CORUM:1220 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | TRF2-Ku complex |
| CORUM:1092 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | PCNA-KU antigen complex |
| CORUM:357 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | DNA-PK-Ku complex |
| CORUM:356 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | DNA-PK-Ku complex |
| CORUM:355 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | DNA-PK-Ku complex |
| CORUM:322 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | DNA-PK-Ku complex |
| CORUM:95 | 5.02777038712e-06 | 1.0 | XRCC6 XRCC5 | Ku antigen-NARG1 complex |
| WP:WP438 | 7.82420796608e-06 | 1.0 | XRCC6 XRCC5 | Non-homologous end joining |
| CORUM:1571 | 1.00555407742e-05 | 1.0 | XRCC6 XRCC5 | Vigilin-DNA-PK-Ku antigen complex |
| CORUM:7217 | 1.00555407742e-05 | 1.0 | XRCC6 XRCC5 | Dysbindin 1-A-DNA-PK-complex |
| CORUM:5235 | 1.00555407742e-05 | 1.0 | XRCC6 XRCC5 | WRN-Ku70-Ku80-PARP1 complex |
| CORUM:5176 | 1.00555407742e-05 | 1.0 | XRCC6 XRCC5 | MGC1-DNA-PKcs-Ku complex |
| KEGG:03450 | 1.13800084426e-05 | 1.0 | XRCC6 XRCC5 | Non-homologous end-joining |
| CORUM:5231 | 1.67592346237e-05 | 1.0 | XRCC6 XRCC5 | 53BP1-containing complex |
| CORUM:5179 | 1.67592346237e-05 | 1.0 | XRCC6 XRCC5 | NCOA6-DNA-PK-Ku-PARP1 complex |
| CORUM:5251 | 2.51388519356e-05 | 1.0 | XRCC6 XRCC5 | Ku-ORC complex |
| CORUM:3102 | 2.51388519356e-05 | 1.0 | XRCC6 XRCC5 | DHX9-ADAR-vigilin-DNA-PK-Ku antigen complex |
| CORUM:1189 | 3.51943927099e-05 | 1.0 | XRCC6 XRCC5 | DNA double-strand break end-joining complex |
| CORUM:1193 | 3.51943927099e-05 | 1.0 | XRCC6 XRCC5 | Rap1 complex |
| CORUM:2766 | 3.51943927099e-05 | 1.0 | XRCC6 XRCC5 | TERF2-RAP1 complex |
| REAC:R-HSA-164843 | 3.51943927099e-05 | 1.0 | XRCC6 XRCC5 | 2-LTR circle formation |
| CORUM:5183 | 4.69258569465e-05 | 1.0 | XRCC6 XRCC5 | DNA-PK-Ku-eIF2-NF90-NF45 complex |
| REAC:R-HSA-162592 | 6.03332446455e-05 | 1.0 | XRCC6 XRCC5 | Integration of provirus |
| CORUM:7285 | 6.03332446455e-05 | 1.0 | XRCC6 XRCC5 | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| REAC:R-HSA-3270619 | 0.000130722030065 | 1.0 | XRCC6 XRCC5 | IRF3-mediated induction of type I IFN |
| REAC:R-HSA-162594 | 0.000152509035076 | 1.0 | XRCC6 XRCC5 | Early Phase of HIV Life Cycle |
| REAC:R-HSA-1834941 | 0.000201110815485 | 1.0 | XRCC6 XRCC5 | STING mediated induction of host immune responses |
| GO:0043564 | 0.00135247023414 | 1.0 | XRCC6 XRCC5 | Ku70:Ku80 complex |
| REAC:R-HSA-1834949 | 0.00327307852202 | 1.0 | XRCC6 XRCC5 | Cytosolic sensors of pathogen-associated DNA |
| REAC:R-HSA-5693571 | 0.00393171644273 | 1.0 | XRCC6 XRCC5 | Nonhomologous End-Joining (NHEJ) |
| GO:0051575 | 0.00450823411379 | 1.0 | XRCC6 XRCC5 | 5'-deoxyribose-5-phosphate lyase activity |
| GO:0071481 | 0.00676235117068 | 1.0 | XRCC6 XRCC5 | cellular response to X-ray |
| GO:0075713 | 0.0126230555186 | 1.0 | XRCC6 XRCC5 | establishment of integrated proviral latency |
| GO:0019043 | 0.0162296428096 | 1.0 | XRCC6 XRCC5 | establishment of viral latency |
| GO:0070419 | 0.0162296428096 | 1.0 | XRCC6 XRCC5 | nonhomologous end joining complex |
| GO:0003691 | 0.0162296428096 | 1.0 | XRCC6 XRCC5 | double-stranded telomeric DNA binding |
| REAC:R-HSA-162587 | 0.0177396498492 | 1.0 | XRCC6 XRCC5 | HIV Life Cycle |
| REAC:R-HSA-5693532 | 0.0224003929981 | 1.0 | XRCC6 XRCC5 | DNA Double-Strand Break Repair |
| GO:0019042 | 0.0247952876258 | 1.0 | XRCC6 XRCC5 | viral latency |
| GO:0000783 | 0.029754345151 | 1.0 | XRCC6 XRCC5 | nuclear telomere cap complex |
| GO:0000782 | 0.029754345151 | 1.0 | XRCC6 XRCC5 | telomere cap complex |
| GO:0010165 | 0.0410249304355 | 1.0 | XRCC6 XRCC5 | response to X-ray |
| REAC:R-HSA-162906 | 0.0414841334642 | 1.0 | XRCC6 XRCC5 | HIV Infection |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| XRCC5 | XRCC6 | 1.0 | 0.949 | hein_WMM bioplex (XRCC6) bioplex_WMM Guru boldt youn_WMM hein (XRCC5,XRCC6) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_05793 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| XRCC5 | HuMAP2_01370 HuMAP2_01667 HuMAP2_02284 HuMAP2_02836 HuMAP2_04529 HuMAP2_05793 |
| XRCC6 | HuMAP2_02284 HuMAP2_02836 HuMAP2_03086 HuMAP2_04529 HuMAP2_05224 HuMAP2_05793 HuMAP2_05863 HuMAP2_06682 |