hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05795
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| APEH | Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) | UniProt NCBI |
| CAPN1 | Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP) | UniProt NCBI |
| CD109 | CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109) | UniProt NCBI |
| LMNB2 | Lamin-B2 | UniProt NCBI |
| ACADVL | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-1-3p | 0.0144936698818 | 0.8 | APEH CAPN1 CD109 ACADVL | hsa-miR-1-3p |
| KEGG:04210 | 0.0327287628992 | 0.4 | LMNB2 CAPN1 | Apoptosis |
| CORUM:6706 | 0.0499494897235 | 0.2 | CAPN1 | CAPN1-HSP90AB1 complex |
| CORUM:6710 | 0.0499494897235 | 0.2 | CAPN1 | Calpain 1 |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CAPN1 | CD109 | 0.351 | 0.537 | bioplex (CAPN1) bioplex_WMM fraction |
| CAPN1 | LMNB2 | 0.333 | 0.525 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| LMNB2 | ACADVL | 0.212 | 0.462 | bioplex_WMM fraction treiber_WMM |
| CAPN1 | APEH | 0.169 | 0.426 | bioplex_WMM fraction treiber_WMM |
| LMNB2 | APEH | 0.049 | 0.294 | bioplex_WMM fraction treiber_WMM |
| CAPN1 | ACADVL | 0.041 | 0.27 | bioplex_WMM fraction boldt_WMM treiber_WMM |
| APEH | ACADVL | 0.007 | 0.001 | bioplex_WMM WMM_only treiber_WMM |
| APEH | CD109 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| CD109 | ACADVL | 0.0 | 0.005 | fraction |
| LMNB2 | CD109 | 0.0 | 0.006 | bioplex_WMM fraction |
Images
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Complex HuMAP2_05795 has an average edge precision of 0.253 which is ranked 5333 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| APEH | HuMAP2_01805 HuMAP2_02186 HuMAP2_05795 |
| CAPN1 | HuMAP2_00660 HuMAP2_01189 HuMAP2_02449 HuMAP2_02830 HuMAP2_05795 |
| CD109 | HuMAP2_02830 HuMAP2_04553 HuMAP2_05795 |
| LMNB2 | HuMAP2_01147 HuMAP2_02186 HuMAP2_02630 HuMAP2_04524 HuMAP2_05795 HuMAP2_06899 |
| ACADVL | HuMAP2_05795 HuMAP2_06935 |