hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05796
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CCSER2 | Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog) | UniProt NCBI |
| NDEL1 | Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1) | UniProt NCBI |
| DIXDC1 | Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1) | UniProt NCBI |
| NDE1 | Nuclear distribution protein nudE homolog 1 (NudE) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-141444 | 0.041754071825 | 0.5 | NDE1 NDEL1 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141424 | 0.041754071825 | 0.5 | NDE1 NDEL1 | Amplification of signal from the kinetochores |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DIXDC1 | NDEL1 | 1.0 | 0.949 | hein_WMM bioplex (NDEL1) bioplex_WMM hein (NDEL1) |
| CCSER2 | NDEL1 | 1.0 | 0.949 | hein_WMM bioplex (NDEL1) bioplex_WMM youn_WMM hein (CCSER2,NDEL1) gupta_WMM |
| NDE1 | NDEL1 | 0.964 | 0.873 | hein_WMM bioplex (NDEL1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| CCSER2 | NDE1 | 0.268 | 0.483 | hein_WMM bioplex_WMM hein (CCSER2) gupta_WMM |
| DIXDC1 | CCSER2 | 0.009 | 0.095 | hein_WMM bioplex_WMM WMM_only |
| DIXDC1 | NDE1 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05796 has an average edge precision of 0.559 which is ranked 2137 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CCSER2 | HuMAP2_00460 HuMAP2_00783 HuMAP2_05796 |
| NDEL1 | HuMAP2_00460 HuMAP2_00783 HuMAP2_05796 |
| DIXDC1 | HuMAP2_00460 HuMAP2_00783 HuMAP2_03819 HuMAP2_05796 |
| NDE1 | HuMAP2_00460 HuMAP2_00783 HuMAP2_05796 |