hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05797
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HNRNPLL | Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) (Stromal RNA-regulating factor) | UniProt NCBI |
| ARPC2 | Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC) | UniProt NCBI |
| ACTR3B | Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4) | UniProt NCBI |
| ARPC4 | Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC) | UniProt NCBI |
| ARPC5 | Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC) | UniProt NCBI |
| ACTR2 | Actin-related protein 2 (Actin-like protein 2) | UniProt NCBI |
| ACTR3 | Actin-related protein 3 (Actin-like protein 3) | UniProt NCBI |
| ARPC1B | Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC) | UniProt NCBI |
| ARPC3 | Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC) | UniProt NCBI |
| ARPC1A | Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) | UniProt NCBI |
| ARPC5L | Actin-related protein 2/3 complex subunit 5-like protein (Arp2/3 complex 16 kDa subunit 2) (ARC16-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005885 | 2.77359793752e-26 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | Arp2/3 protein complex |
| CORUM:27 | 6.93111371734e-22 | 0.636363636364 | ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Arp2/3 protein complex |
| GO:0034314 | 8.64843841299e-20 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | Arp2/3 complex-mediated actin nucleation |
| GO:0045010 | 5.57672792722e-19 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | actin nucleation |
| REAC:R-HSA-5663213 | 1.41381438074e-17 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | RHO GTPases Activate WASPs and WAVEs |
| REAC:R-HSA-3928662 | 3.6931258188e-17 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | EPHB-mediated forward signaling |
| GO:0030838 | 4.77970934734e-16 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of actin filament polymerization |
| REAC:R-HSA-2029482 | 1.32632374523e-15 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Regulation of actin dynamics for phagocytic cup formation |
| GO:0051015 | 2.45541592049e-15 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | actin filament binding |
| REAC:R-HSA-2029480 | 1.72728134851e-14 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Fcgamma receptor (FCGR) dependent phagocytosis |
| GO:0032273 | 2.15235474965e-14 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of protein polymerization |
| REAC:R-HSA-2682334 | 3.15829778874e-14 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | EPH-Ephrin signaling |
| GO:0030833 | 4.74907248971e-14 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of actin filament polymerization |
| WP:WP2272 | 9.17504292768e-14 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Pathogenic Escherichia coli infection |
| GO:0008064 | 1.50504828972e-13 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of actin polymerization or depolymerization |
| GO:0030832 | 1.63509387545e-13 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of actin filament length |
| GO:0030041 | 2.44724676946e-13 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | actin filament polymerization |
| KEGG:05131 | 2.82837809133e-13 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Shigellosis |
| KEGG:05132 | 3.95668026095e-13 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Salmonella infection |
| KEGG:05100 | 7.40263804235e-13 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Bacterial invasion of epithelial cells |
| GO:0008154 | 1.19541535908e-12 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | actin polymerization or depolymerization |
| GO:1902905 | 1.27676531721e-12 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of supramolecular fiber organization |
| GO:0003779 | 1.39919670353e-12 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | actin binding |
| GO:0032271 | 1.65357942554e-12 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of protein polymerization |
| GO:0038094 | 2.29413737583e-12 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Fc-gamma receptor signaling pathway |
| GO:0002433 | 2.29413737583e-12 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis |
| GO:0038096 | 2.29413737583e-12 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Fc-gamma receptor signaling pathway involved in phagocytosis |
| GO:0002431 | 2.86028631497e-12 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Fc receptor mediated stimulatory signaling pathway |
| GO:0048013 | 2.86028631497e-12 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | ephrin receptor signaling pathway |
| KEGG:04666 | 2.87405095356e-12 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Fc gamma R-mediated phagocytosis |
| GO:0051495 | 3.44460246467e-12 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of cytoskeleton organization |
| GO:0110053 | 7.56330753627e-12 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of actin filament organization |
| GO:0031334 | 1.55846627175e-11 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of protein complex assembly |
| GO:0051258 | 3.48930976217e-11 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | protein polymerization |
| GO:0032535 | 6.44278792179e-11 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of cellular component size |
| GO:0035861 | 1.02773416653e-10 | 0.636363636364 | ARPC1A ARPC2 ARPC3 ACTR3 ARPC4 ARPC5 ACTR2 | site of double-strand break |
| GO:0032956 | 1.39185397171e-10 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of actin cytoskeleton organization |
| GO:1902903 | 1.62364796685e-10 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of supramolecular fiber organization |
| REAC:R-HSA-8856828 | 2.18168596808e-10 | 0.636363636364 | ARPC1A ARPC2 ARPC3 ACTR3 ARPC4 ARPC5 ACTR2 | Clathrin-mediated endocytosis |
| KEGG:05130 | 4.24517318626e-10 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Pathogenic Escherichia coli infection |
| GO:0032970 | 4.45695324866e-10 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of actin filament-based process |
| GO:0090066 | 4.61126163144e-10 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of anatomical structure size |
| KEGG:04810 | 6.2627552872e-10 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Regulation of actin cytoskeleton |
| GO:0090734 | 8.21692822701e-10 | 0.636363636364 | ARPC1A ARPC2 ARPC3 ACTR3 ARPC4 ARPC5 ACTR2 | site of DNA damage |
| GO:0007015 | 9.15996278691e-10 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | actin filament organization |
| REAC:R-HSA-195258 | 1.07549984271e-09 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | RHO GTPase Effectors |
| GO:0038093 | 1.32134111006e-09 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Fc receptor signaling pathway |
| GO:0043254 | 1.89085118132e-09 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of protein complex assembly |
| KEGG:04144 | 2.78037190511e-09 | 0.636363636364 | ARPC1A ARPC5L ARPC3 ARPC1B ARPC4 ARPC5 ARPC2 | Endocytosis |
| GO:0005200 | 3.75277774579e-09 | 0.636363636364 | ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | structural constituent of cytoskeleton |
| GO:0006909 | 5.04215248839e-09 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | phagocytosis |
| GO:0044089 | 7.43116820111e-09 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of cellular component biogenesis |
| GO:0051493 | 1.26396426161e-08 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of cytoskeleton organization |
| GO:0015629 | 1.29389855037e-08 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | actin cytoskeleton |
| REAC:R-HSA-194315 | 1.51811235699e-08 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Signaling by Rho GTPases |
| GO:0008092 | 3.22145113925e-08 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | cytoskeletal protein binding |
| REAC:R-HSA-422475 | 6.20131016002e-08 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Axon guidance |
| GO:0044877 | 7.40762602146e-08 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | protein-containing complex binding |
| GO:0010638 | 7.62898708455e-08 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of organelle organization |
| GO:0002429 | 1.17536745008e-07 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | immune response-activating cell surface receptor signaling pathway |
| GO:0030036 | 1.26096865434e-07 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | actin cytoskeleton organization |
| GO:0097435 | 1.28396933665e-07 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | supramolecular fiber organization |
| GO:0002768 | 2.0946004961e-07 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | immune response-regulating cell surface receptor signaling pathway |
| GO:0030029 | 4.45777553013e-07 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | actin filament-based process |
| GO:0044087 | 1.60845893203e-06 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of cellular component biogenesis |
| GO:0002757 | 2.41222171529e-06 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | immune response-activating signal transduction |
| GO:0002764 | 3.65892252402e-06 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | immune response-regulating signaling pathway |
| REAC:R-HSA-168249 | 5.16380660972e-06 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Innate Immune System |
| REAC:R-HSA-1266738 | 6.35465813457e-06 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Developmental Biology |
| GO:0002253 | 7.65869982186e-06 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | activation of immune response |
| REAC:R-HSA-199991 | 8.37499384313e-06 | 0.636363636364 | ARPC1A ARPC2 ARPC3 ACTR3 ARPC4 ARPC5 ACTR2 | Membrane Trafficking |
| HPA:028010_23 | 9.32632226846e-06 | 0.545454545455 | ARPC2 ARPC1B ARPC3 ACTR3 HNRNPLL ACTR2 | lymph node; germinal center cells[Approved,High] |
| REAC:R-HSA-5653656 | 1.21177317663e-05 | 0.636363636364 | ARPC1A ARPC2 ARPC3 ACTR3 ARPC4 ARPC5 ACTR2 | Vesicle-mediated transport |
| GO:0051130 | 1.22232996483e-05 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | positive regulation of cellular component organization |
| GO:0007169 | 1.39210652641e-05 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | transmembrane receptor protein tyrosine kinase signaling pathway |
| GO:0034622 | 1.49670365516e-05 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | cellular protein-containing complex assembly |
| GO:0050778 | 3.00456417848e-05 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | positive regulation of immune response |
| GO:0033043 | 3.71805139842e-05 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of organelle organization |
| GO:0005925 | 6.14236407021e-05 | 0.636363636364 | ARPC5L ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | focal adhesion |
| GO:0005924 | 6.38853023766e-05 | 0.636363636364 | ARPC5L ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | cell-substrate adherens junction |
| GO:0030055 | 7.04108770042e-05 | 0.636363636364 | ARPC5L ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | cell-substrate junction |
| GO:0007010 | 8.55098312449e-05 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | cytoskeleton organization |
| HPA:028020_23 | 8.5667056022e-05 | 0.545454545455 | ARPC2 ARPC1B ARPC3 ACTR3 HNRNPLL ACTR2 | lymph node; non-germinal center cells[Approved,High] |
| HPA:056020_23 | 0.000115718762935 | 0.545454545455 | ARPC2 ARPC1B ARPC3 ACTR3 HNRNPLL ACTR2 | tonsil; non-germinal center cells[Approved,High] |
| GO:0050776 | 0.000184269624723 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | regulation of immune response |
| GO:0007167 | 0.000186334758689 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | enzyme linked receptor protein signaling pathway |
| GO:0002684 | 0.000208120668948 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | positive regulation of immune system process |
| GO:0044430 | 0.000303715640978 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | cytoskeletal part |
| GO:0005912 | 0.00035747053878 | 0.636363636364 | ARPC5L ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | adherens junction |
| GO:0070161 | 0.000421723272005 | 0.636363636364 | ARPC5L ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | anchoring junction |
| GO:0005198 | 0.000510115903438 | 0.636363636364 | ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | structural molecule activity |
| GO:0070358 | 0.000523632447094 | 0.272727272727 | ACTR3 ARPC3 ARPC2 | actin polymerization-dependent cell motility |
| GO:0070062 | 0.00060016200741 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | extracellular exosome |
| GO:1903561 | 0.000654864188494 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | extracellular vesicle |
| GO:0043230 | 0.000664968809918 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | extracellular organelle |
| GO:0002252 | 0.000756760323498 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | immune effector process |
| REAC:R-HSA-168256 | 0.000957399550421 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Immune System |
| GO:0065003 | 0.00105234983398 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | protein-containing complex assembly |
| HPA:002020_21 | 0.00107430397439 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | appendix; lymphoid tissue[Approved,Low] |
| HPA:050010_21 | 0.00159305457153 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | spleen; cells in red pulp[Approved,Low] |
| HPA:056010_23 | 0.00192547612209 | 0.454545454545 | ACTR3 ARPC3 ARPC2 ACTR2 ARPC1B | tonsil; germinal center cells[Approved,High] |
| GO:0005856 | 0.00203520096664 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | cytoskeleton |
| REAC:R-HSA-162582 | 0.00226108430319 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | Signal Transduction |
| TF:M09606_1 | 0.00251826624663 | 0.818181818182 | ACTR2 ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 |
| GO:0061024 | 0.00288937116219 | 0.636363636364 | ARPC1A ARPC2 ARPC3 ACTR3 ARPC4 ARPC5 ACTR2 | membrane organization |
| KEGG:05135 | 0.00294450892219 | 0.272727272727 | ACTR3 ACTR2 ACTR3B | Yersinia infection |
| GO:0002682 | 0.00325247609121 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | regulation of immune system process |
| HPA:007030_22 | 0.00535958773726 | 0.636363636364 | ACTR2 ARPC1A ARPC5L ARPC3 HNRNPLL ARPC5 ARPC2 | cerebellum; cells in molecular layer[Approved,Medium] |
| HPA:022020_22 | 0.00536156309377 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | hippocampus; neuronal cells[Approved,Medium] |
| GO:0043933 | 0.00555982609422 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | protein-containing complex subunit organization |
| HPA:056010_21 | 0.00581628612269 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | tonsil; germinal center cells[Approved,Low] |
| GO:0030054 | 0.00604791278478 | 0.636363636364 | ARPC5L ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | cell junction |
| KEGG:04530 | 0.00634381757845 | 0.272727272727 | ACTR3 ACTR2 ACTR3B | Tight junction |
| HPA:006010_21 | 0.00702300104324 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | caudate; glial cells[Approved,Low] |
| GO:0051128 | 0.00722718112566 | 0.818181818182 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ARPC4 | regulation of cellular component organization |
| GO:0005615 | 0.00972059827024 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | extracellular space |
| HPA:003010_21 | 0.0111146485547 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | bone marrow; hematopoietic cells[Approved,Low] |
| HPA:035010_20 | 0.0117160429013 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | placenta; decidual cells[Approved,Not detected] |
| HPA:007010_22 | 0.0141332746637 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | cerebellum; Purkinje cells[Approved,Medium] |
| HPA:035010_21 | 0.0142591119884 | 0.727272727273 | ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | placenta; decidual cells[Approved,Low] |
| GO:0044421 | 0.0168175647555 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | extracellular region part |
| HPA:035010_22 | 0.0191767954641 | 0.636363636364 | ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | placenta; decidual cells[Approved,Medium] |
| HPA:008030_22 | 0.0208908784109 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | cerebral cortex; neuronal cells[Approved,Medium] |
| HPA:028020_22 | 0.0245105681672 | 0.636363636364 | ARPC1A ARPC2 ARPC1B ARPC3 ACTR3 HNRNPLL ACTR2 | lymph node; non-germinal center cells[Approved,Medium] |
| HPA:004020_22 | 0.0247868253226 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | breast; glandular cells[Approved,Medium] |
| HPA:027020_21 | 0.0254008158377 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | lung; pneumocytes[Approved,Low] |
| HPA:004020_21 | 0.0262057397341 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | breast; glandular cells[Approved,Low] |
| HPA:024010_21 | 0.0273212067018 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | kidney; cells in glomeruli[Approved,Low] |
| HPA:050020_22 | 0.0273373577924 | 0.545454545455 | ARPC2 ARPC1B ARPC3 ACTR3 HNRNPLL ACTR2 | spleen; cells in white pulp[Approved,Medium] |
| HPA:035020_21 | 0.0284108967339 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | placenta; trophoblastic cells[Approved,Low] |
| GO:0006955 | 0.0311079267074 | 0.727272727273 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5 ARPC4 | immune response |
| HPA:056020_22 | 0.0331013737435 | 0.636363636364 | ARPC1A ARPC2 ARPC1B ARPC3 ACTR3 HNRNPLL ACTR2 | tonsil; non-germinal center cells[Approved,Medium] |
| GO:0005576 | 0.0381048669645 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | extracellular region |
| HPA:029010_21 | 0.039179637984 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | nasopharynx; respiratory epithelial cells[Approved,Low] |
| HPA:026010_21 | 0.0404074812929 | 0.636363636364 | ACTR2 ARPC1A ARPC5L ACTR3 HNRNPLL ARPC5 ARPC2 | liver; bile duct cells[Approved,Low] |
| HPA:015010_21 | 0.0458318470582 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | epididymis; glandular cells[Approved,Low] |
| HPA:050010_22 | 0.0464835237945 | 0.545454545455 | ARPC2 ARPC1B ARPC3 ACTR3 HNRNPLL ACTR2 | spleen; cells in red pulp[Approved,Medium] |
| GO:0031982 | 0.0464899471098 | 0.909090909091 | ARPC1A ACTR2 ARPC3 ACTR3 ARPC2 ARPC1B ARPC5L ARPC5 ACTR3B ARPC4 | vesicle |
| HPA:018010_21 | 0.0470965094118 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | fallopian tube; glandular cells[Approved,Low] |
| HPA:035020_22 | 0.0474190193756 | 0.727272727273 | ARPC1A ARPC5L ARPC3 ACTR3 ARPC2 HNRNPLL ARPC5 ACTR2 | placenta; trophoblastic cells[Approved,Medium] |
| HPA:057010_21 | 0.0474916839614 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | urinary bladder; urothelial cells[Approved,Low] |
| HPA:053020_21 | 0.0499237599832 | 0.818181818182 | ARPC1A ARPC5L ARPC3 HNRNPLL ACTR3 ARPC2 ARPC1B ARPC5 ACTR2 | testis; cells in seminiferous ducts[Approved,Low] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACTR3 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3,ARPC3) bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| ARPC4 | ACTR3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| ARPC1B | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru fraction treiber_WMM |
| ACTR2 | ARPC4 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (ACTR2) gupta_WMM fraction treiber_WMM |
| ACTR3 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM gupta_WMM fraction |
| ACTR2 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru hein (ACTR2) gupta_WMM fraction |
| ACTR2 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru hein (ACTR2) Malo fraction treiber_WMM |
| ACTR2 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru hein (ACTR2) gupta_WMM fraction treiber_WMM |
| ARPC3 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ARPC5 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ARPC5) bioplex_WMM Guru fraction |
| ACTR2 | ARPC1A | 1.0 | 0.949 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru hein (ACTR2) gupta_WMM fraction |
| ARPC4 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ARPC2 | ARPC1A | 1.0 | 0.949 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ARPC4 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru fraction boldt_WMM treiber_WMM |
| ARPC3 | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru fraction |
| ARPC5 | ACTR3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3,ARPC5) bioplex_WMM fraction |
| ARPC4 | ARPC5 | 1.0 | 0.949 | hein_WMM bioplex (ARPC5) bioplex_WMM Guru fraction |
| ACTR3 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ACTR3,ARPC1B) bioplex_WMM Malo fraction boldt_WMM treiber_WMM |
| ARPC5 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3,ARPC5) bioplex_WMM Guru fraction |
| ARPC4 | ARPC1A | 1.0 | 0.949 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru gupta_WMM fraction |
| ARPC4 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ARPC5 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B,ARPC5) bioplex_WMM Guru fraction |
| ACTR2 | ACTR3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM hein (ACTR2) Malo gupta_WMM fraction treiber_WMM |
| ACTR3 | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM fraction |
| ARPC2 | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru fraction |
| ARPC1B | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru fraction |
| ACTR3 | ARPC1A | 0.999 | 0.949 | hein_WMM bioplex (ACTR3,ARPC1A) bioplex_WMM gupta_WMM fraction |
| ARPC3 | ARPC1A | 0.999 | 0.949 | hein_WMM bioplex (ARPC1A,ARPC3) bioplex_WMM Guru gupta_WMM fraction |
| ACTR2 | ARPC5L | 0.999 | 0.946 | hein_WMM bioplex_WMM Guru hein (ACTR2) fraction |
| ARPC1B | ARPC3 | 0.999 | 0.945 | hein_WMM bioplex (ARPC1B,ARPC3) bioplex_WMM Guru fraction |
| ARPC5 | ARPC1A | 0.995 | 0.924 | hein_WMM bioplex (ARPC1A,ARPC5) bioplex_WMM Guru fraction |
| ARPC1A | ARPC5L | 0.995 | 0.924 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru fraction |
| ACTR2 | ARPC5 | 0.969 | 0.88 | hein_WMM bioplex (ARPC5) bioplex_WMM Guru hein (ACTR2) fraction |
| ARPC4 | ARPC5L | 0.962 | 0.87 | hein_WMM bioplex_WMM Guru fraction |
| ARPC1A | ACTR3B | 0.816 | 0.773 | bioplex (ACTR3B,ARPC1A) bioplex_WMM |
| HNRNPLL | ARPC2 | 0.744 | 0.74 | gupta_WMM fraction |
| ACTR2 | HNRNPLL | 0.686 | 0.712 | youn_WMM gupta_WMM fraction treiber_WMM |
| ARPC3 | ACTR3B | 0.659 | 0.696 | bioplex (ACTR3B,ARPC3) bioplex_WMM |
| HNRNPLL | ACTR3 | 0.507 | 0.627 | fraction treiber_WMM |
| ARPC4 | ACTR3B | 0.298 | 0.498 | bioplex (ACTR3B) bioplex_WMM youn_WMM |
| HNRNPLL | ARPC4 | 0.276 | 0.487 | bioplex_WMM youn_WMM gupta_WMM fraction |
| ARPC5L | ACTR3B | 0.219 | 0.466 | bioplex (ACTR3B) bioplex_WMM |
| ARPC2 | ACTR3B | 0.178 | 0.438 | bioplex (ACTR3B) bioplex_WMM |
| ARPC1B | ACTR3B | 0.161 | 0.417 | bioplex (ACTR3B,ARPC1B) bioplex_WMM |
| ACTR2 | ACTR3B | 0.129 | 0.399 | bioplex (ACTR3B) bioplex_WMM youn_WMM |
| ARPC5 | ACTR3B | 0.095 | 0.359 | bioplex (ACTR3B,ARPC5) bioplex_WMM |
| HNRNPLL | ARPC3 | 0.083 | 0.351 | gupta_WMM fraction |
| HNRNPLL | ARPC1A | 0.061 | 0.336 | bioplex_WMM fraction |
| ACTR3 | ACTR3B | 0.022 | 0.197 | bioplex (ACTR3,ACTR3B) bioplex_WMM |
| ARPC5 | ARPC5L | 0.014 | 0.141 | hein_WMM bioplex_WMM WMM_only |
| HNRNPLL | ARPC1B | 0.012 | 0.15 | bioplex_WMM fraction treiber_WMM |
| HNRNPLL | ACTR3B | 0.007 | 0.0 | youn_WMM WMM_only |
| HNRNPLL | ARPC5L | 0.004 | 0.008 | fraction |
| HNRNPLL | ARPC5 | 0.0 | 0.009 | fraction |
| ARPC1B | ARPC1A | 0.0 | 0.01 | hein_WMM bioplex_WMM fraction |
Images
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Complex HuMAP2_05797 has an average edge precision of 0.725 which is ranked 1294 out of all 6965 complexes.
Related Complexes