hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05809
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein) | UniProt NCBI |
| UBE2N | Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2756 | 1.67592346237e-06 | 1.0 | UBE2N UBE2V2 | Ubiquitin ligase (UBE2N, UBE2V2) |
| CORUM:7051 | 5.02777038712e-06 | 1.0 | UBE2N UBE2V2 | OTUB1-UBC13-MMS2 complex |
| GO:0031372 | 0.000450823411379 | 1.0 | UBE2N UBE2V2 | UBC13-MMS2 complex |
| REAC:R-HSA-5696395 | 0.00151335888652 | 1.0 | UBE2N UBE2V2 | Formation of Incision Complex in GG-NER |
| REAC:R-HSA-8866654 | 0.00258092213206 | 1.0 | UBE2N UBE2V2 | E3 ubiquitin ligases ubiquitinate target proteins |
| REAC:R-HSA-5693571 | 0.00393171644273 | 1.0 | UBE2N UBE2V2 | Nonhomologous End-Joining (NHEJ) |
| REAC:R-HSA-8852135 | 0.00465068760809 | 1.0 | UBE2N UBE2V2 | Protein ubiquitination |
| REAC:R-HSA-5693565 | 0.00477638186777 | 1.0 | UBE2N UBE2V2 | Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| REAC:R-HSA-5693606 | 0.00490375205091 | 1.0 | UBE2N UBE2V2 | DNA Double Strand Break Response |
| REAC:R-HSA-5696399 | 0.00584226918984 | 1.0 | UBE2N UBE2V2 | Global Genome Nucleotide Excision Repair (GG-NER) |
| REAC:R-HSA-69473 | 0.00732546145404 | 1.0 | UBE2N UBE2V2 | G2/M DNA damage checkpoint |
| REAC:R-HSA-5693607 | 0.00780309964082 | 1.0 | UBE2N UBE2V2 | Processing of DNA double-strand break ends |
| REAC:R-HSA-5696398 | 0.0100471611569 | 1.0 | UBE2N UBE2V2 | Nucleotide Excision Repair |
| REAC:R-HSA-5693567 | 0.014052618232 | 1.0 | UBE2N UBE2V2 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| REAC:R-HSA-5693538 | 0.0153849773846 | 1.0 | UBE2N UBE2V2 | Homology Directed Repair |
| GO:0031371 | 0.0162296428096 | 1.0 | UBE2N UBE2V2 | ubiquitin conjugating enzyme complex |
| REAC:R-HSA-5693532 | 0.0224003929981 | 1.0 | UBE2N UBE2V2 | DNA Double-Strand Break Repair |
| REAC:R-HSA-69481 | 0.023229975112 | 1.0 | UBE2N UBE2V2 | G2/M Checkpoints |
| CORUM:6025 | 0.0499173803268 | 0.5 | UBE2N | Ubiquitin-conjugating enzyme E2 (UBC13-UEV1A) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UBE2V2 | UBE2N | 0.988 | 0.901 | bioplex_WMM boldt (UBE2N) fraction boldt_WMM |
Images
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Complex HuMAP2_05809 has an average edge precision of 0.901 which is ranked 546 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UBE2V2 | HuMAP2_03473 HuMAP2_04263 HuMAP2_05809 HuMAP2_05915 |
| UBE2N | HuMAP2_05809 HuMAP2_05915 HuMAP2_06063 |