hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05812
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SMC2 | Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) | UniProt NCBI |
| SMC4 | Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5239 | 1.67592346237e-06 | 1.0 | SMC4 SMC2 | CAP(C)-CAP(E) complex |
| CORUM:353 | 5.02777038712e-06 | 1.0 | SMC4 SMC2 | DNA ligase IV-condensin complex |
| CORUM:10 | 1.67592346237e-05 | 1.0 | SMC4 SMC2 | Condensin I complex |
| CORUM:157 | 1.67592346237e-05 | 1.0 | SMC4 SMC2 | Condensin I complex |
| CORUM:160 | 1.67592346237e-05 | 1.0 | SMC4 SMC2 | Condensin II |
| CORUM:167 | 1.67592346237e-05 | 1.0 | SMC4 SMC2 | Condensin I complex |
| CORUM:49 | 3.51943927099e-05 | 1.0 | SMC4 SMC2 | DNMT3B complex |
| CORUM:159 | 3.51943927099e-05 | 1.0 | SMC4 SMC2 | Condensin I-PARP-1-XRCC1 complex |
| REAC:R-HSA-2514853 | 9.21757904306e-05 | 1.0 | SMC4 SMC2 | Condensation of Prometaphase Chromosomes |
| REAC:R-HSA-2299718 | 0.00428366036983 | 1.0 | SMC4 SMC2 | Condensation of Prophase Chromosomes |
| GO:0000796 | 0.00946729163895 | 1.0 | SMC4 SMC2 | condensin complex |
| REAC:R-HSA-68875 | 0.0144900342557 | 1.0 | SMC4 SMC2 | Mitotic Prophase |
| REAC:R-HSA-68877 | 0.0304096312248 | 1.0 | SMC4 SMC2 | Mitotic Prometaphase |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SMC4 | SMC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC4) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_05812 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SMC2 | HuMAP2_01363 HuMAP2_02781 HuMAP2_05812 |
| SMC4 | HuMAP2_01363 HuMAP2_02781 HuMAP2_05812 |